Výsledky vyhledávání - "A. M. V. Miles"

Pharmacokinetics of Oral and Transdermal Triprolidine

Autor: William A. Wargin, R. Balasubramanian, M. F. Frosolono, M. F. Smith, K. A. Pappa, A. W. Pittman, J. W. A. Findlay, M. V. Miles, R. I. Poust, S. H. Grossman

Publikováno v: The Journal of Clinical Pharmacology. 30:572-575

In this open, nonrandomized, three-way crossover study, six healthy male volunteers received single doses of triprolidine (TPL) hydrochloride syrup orally (2.5 mg) and wore transdermal TPL patches (5 mg and 10 mg doses) to compare the pharmacokinetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b81c9eb59b6074302f263cca08fc6f
https://doi.org/10.1002/j.1552-4604.1990.tb03623.x

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HPLC analysis of reduced and oxidized coenzyme Q(10) in human plasma

Autor: P H, Tang, M V, Miles, A, DeGrauw, A, Hershey, A, Pesce

Publikováno v: Clinical chemistry. 47(2)

The percentage of reduced coenzyme Q(10) (CoQ(10)H(2)) in total coenzyme Q(10) (TQ(10)) is decreased in plasma of patients with prematurity, hyperlipidemia, and liver disease. CoQ(10)H(2) is, however, easily oxidized and difficult to measure, and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::090660ee6469e460de7777364979a219
https://pubmed.ncbi.nlm.nih.gov/11159774

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Vancomycin-binding characteristics in patients with serious infections

Autor: L, Li, M V, Miles, H, Lakkis, A L, Zaritsky

Publikováno v: Pharmacotherapy. 16(6)

To examine the extent, variability, and factors affecting vancomycin protein binding.Prospective, open-label, cohort study.A general hospital.Forty-four adults [mean (+/- SD) age 50.9 +/- 17.1 yrs, range 16.8-92.0 yrs] with serious infections.Unbound

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8868fb66fccaab562d5b5bcc8390c22f
https://pubmed.ncbi.nlm.nih.gov/8947974

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Increased serum clearance and degradation of 125I-labeled IGF-I in protein-restricted rats

Autor: M V Miles, Jean-Paul Thissen, Marsha L. Davenport, Louis E. Underwood, Jolanta B. Pucilowska

Publikováno v: The American journal of physiology. 262(4 Pt 1)

Dietary protein restriction in young rats stunts growth and decreases serum insulin-like growth factor I (IGF-I) concentrations. To investigate the possibility of a diet-induced accelerated clearance of IGF-I, the clearance of 125I-labeled IGF-I was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e608e841d7a725bbc5ddf3066c0f004
https://pubmed.ncbi.nlm.nih.gov/1566828

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Methsuximide for intractable childhood seizures

Autor: M B, Tennison, R S, Greenwood, M V, Miles

Publikováno v: Pediatrics. 87(2)

Methsuximide was added to the therapeutic regimens of 25 children with intractable epilepsy. In 15 patients the drug was well tolerated and resulted in a 50% or greater reduction in seizure frequency. No serious or irreversible adverse effects were s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::872979f78c511b6446f2ad4a6ffa049b
https://pubmed.ncbi.nlm.nih.gov/1956755

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Regulation of serum insulin-like growth factor-I (IGF-I) and IGF binding proteins during rat pregnancy

Autor: Louis E. Underwood, David R. Clemmons, M V Miles, Marsha L. Davenport, Cecilia Camacho-Hübner, A J D'Ercole

Publikováno v: Endocrinology. 127(3)

Serum concentrations of insulin-like growth factor-I (IGF-I) in rats are reduced dramatically in the latter half of pregnancy, decreasing from 1758 +/- 356 ng/ml at 12 days of pregnancy (mean +/- SD) to 761 +/- 192 ng/ml at 15 days. After parturition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a33a358c46a56219fac9fc5ca6cd73e
https://pubmed.ncbi.nlm.nih.gov/1696882

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Rapid loading of critically ill patients with carbamazepine suspension

Autor: M V, Miles, S T, Lawless, M B, Tennison, A L, Zaritsky, R S, Greenwood

Publikováno v: Pediatrics. 86(2)

To determine the rate and factors that affect carbamazepine absorption, six patients being treated in the pediatric intensive care unit for frequent seizures received loading doses (7.4 to 10.4 mg/kg) of carbamazepine suspension by either nasogastric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bb36863f60dee474dfe3f30ddc5092be
https://pubmed.ncbi.nlm.nih.gov/2371100

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