Zobrazeno 1 - 10
of 25
pro vyhledávání: '"A. M. Tverskoi"'
Autor:
Sergei N. Orlov, Artem M. Tverskoi, Svetlana V. Sidorenko, Larisa V. Smolyaninova, Olga D. Lopina, Nickolai O. Dulin, Elizaveta A. Klimanova
Publikováno v:
Genes and Diseases, Vol 8, Iss 3, Pp 259-271 (2021)
With an exception of few reports, the plasma concentration of ouabain and marinobufagenin, mostly studied cardiotonic steroids (CTS) assessed by immunoassay techniques, is less than 1 nM. During the last 3 decades, the implication of these endogenous
Externí odkaz:
https://doaj.org/article/06ca50ef462249b5824f467527df1996
Autor:
Aleksandra V. Petrovskaya, Artem M. Tverskoi, Evgeny P. Barykin, Kseniya B. Varshavskaya, Alexandra A. Dalina, Vladimir A. Mitkevich, Alexander A. Makarov, Irina Yu. Petrushanko
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 183 (2022)
The Alzheimer’s disease (AD)-associated breakdown of the blood–brain barrier (BBB) promotes the accumulation of beta-amyloid peptide (Aβ) in the brain as the BBB cells provide Aβ transport from the brain parenchyma to the blood, and vice versa.
Externí odkaz:
https://doaj.org/article/34a0ea7c6f324f28a70c6ecef06ebc1a
Autor:
Irina Yu. Petrushanko, Artem M. Tverskoi, Evgeny P. Barykin, Aleksandra V. Petrovskaya, Maria A. Strelkova, Olga G. Leonova, Anastasia A. Anashkina, Anna P. Tolstova, Alexei A. Adzhubei, Anna Yu. Bogdanova, Alexander A. Makarov, Vladimir A. Mitkevich
Publikováno v:
Cells, Vol 11, Iss 17, p 2753 (2022)
Beta-amyloid (Aβ) has a dual role, both as an important factor in the pathology of Alzheimer’s disease and as a regulator in brain physiology. The inhibitory effect of Aβ42 oligomers on Na,K-ATPase contributes to neuronal dysfunction in Alzheimer
Externí odkaz:
https://doaj.org/article/b59b71b531fe4e4fb32469fb7869285c
Autor:
A. V. Petrovskaya, E. P. Barykin, A. M. Tverskoi, K. B. Varshavskaya, V. A. Mitkevich, I. Yu. Petrushanko, A. A. Makarov
Publikováno v:
Molecular Biology. 56:1020-1027
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce34a4248c28f1eaf51a4e793deacabe
https://doi.org/10.1134/s0026893322060140
https://doi.org/10.1134/s0026893322060140
Autor:
Artem M. Tverskoi, Yuri M. Poluektov, Elizaveta A. Klimanova, Vladimir A. Mitkevich, Alexander A. Makarov, Sergei N. Orlov, Irina Yu. Petrushanko, Olga D. Lopina
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13268 (2021)
Cardiotonic steroids (CTSs) are specific inhibitors of Na,K-ATPase (NKA). They induce diverse physiological effects and were investigated as potential drugs in heart diseases, hypertension, neuroinflammation, antiviral and cancer therapy. Here, we co
Externí odkaz:
https://doaj.org/article/0d43722bfab145909cf5d9a1e94c8612
Autor:
Elizaveta A. Klimanova, Svetlana V. Sidorenko, Polina A. Abramicheva, Artem M. Tverskoi, Sergei N. Orlov, Olga D. Lopina
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 7992 (2020)
Stimulus-dependent elevation of intracellular Ca2+ affects gene expression via well-documented calmodulin-mediated signaling pathways. Recently, we found that the addition of extra- and intracellular Ca2+ chelators increased, rather than decreased, t
Externí odkaz:
https://doaj.org/article/0bc8e6e2c2094d6198f6dbea2f547bab
Autor:
Svetlana V. Sidorenko, E. A. Klimanova, Nickolai O. Dulin, Sergei N. Orlov, Artem M. Tverskoi, Olga D. Lopina, Larisa V. Smolyaninova
Publikováno v:
Genes & Diseases
Genes and Diseases, Vol 8, Iss 3, Pp 259-271 (2021)
Genes and Diseases, Vol 8, Iss 3, Pp 259-271 (2021)
With an exception of few reports, the plasma concentration of ouabain and marinobufagenin, mostly studied cardiotonic steroids (CTS) assessed by immunoassay techniques, is less than 1 nM. During the last 3 decades, the implication of these endogenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4eb3162fc4390a48554ae4ca53d150
https://doi.org/10.1016/j.gendis.2020.01.008
https://doi.org/10.1016/j.gendis.2020.01.008
Publikováno v:
Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology. 14:54-60
The affinity of rodent Na+,K+-ATPase α1-subunit to cardiotonic steroids (CTS) is known to be approximately 1000-fold less than the affinity of Na+,K+-ATPase α1-subunit from other mammals. The CTS-resistant isoform of Na+,K+-ATPase α1-subunit (α1R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f73b98ab085640548dac6298e521a96
https://doi.org/10.1134/s1990747820010080
https://doi.org/10.1134/s1990747820010080
Autor:
Olga D. Lopina, E. A. Klimanova, Artem M. Tverskoi, Sergei N. Orlov, P A Abramicheva, Svetlana V. Sidorenko
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 21
International Journal of Molecular Sciences, Vol 21, Iss 7992, p 7992 (2020)
Volume 21
Issue 21
International Journal of Molecular Sciences, Vol 21, Iss 7992, p 7992 (2020)
Stimulus-dependent elevation of intracellular Ca2+ affects gene expression via well-documented calmodulin-mediated signaling pathways. Recently, we found that the addition of extra- and intracellular Ca2+ chelators increased, rather than decreased, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd392002b39f88e6c2cfe454bbbeab0f
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Ouabain is of cardiotonic steroids (CTS) family that is plant-derived compounds and is known for many years as therapeutic and cytotoxic agents. They are specific inhibitors of Na,K-ATPase, the enzyme, which pumps Na+ and K+ across plasma membrane of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98c4c64e0da5319c7d26cf91485e570
https://doi.org/10.3389/fphys.2020.01060
https://doi.org/10.3389/fphys.2020.01060