Zobrazeno 1 - 9
of 9
pro vyhledávání: '"A. M. Tumilovich"'
Autor:
Alexey V. Kuzikov, Rami A. Masamrekh, Tatiana A. Filippova, Anastasiya M. Tumilovich, Natallia V. Strushkevich, Andrei A. Gilep, Yulia Yu. Khudoklinova, Victoria V. Shumyantseva
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 152 (2024)
We describe a bielectrode system for evaluation of the electrocatalytic activity of cytochrome P450 2E1 (CYP2E1) towards chlorzoxazone. One electrode of the system was employed to immobilize Bactosomes with human CYP2E1, cytochrome P450 reductase (CP
Externí odkaz:
https://doaj.org/article/9be09772c041412986e3ecb53905337b
Autor:
Anton S. Rudovich, Miroslav Peřina, Anastasiya V. Krech, Maria Y. Novozhilova, Anastasia M. Tumilovich, Tatyana V. Shkel, Irina P. Grabovec, Miroslav Kvasnica, Lukáš Mada, Maria G. Zavialova, Arif R. Mekhtiev, Radek Jorda, Vladimir N. Zhabinskii, Vladimir A. Khripach
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13534 (2022)
Steroids with a nitrogen-containing heterocycle in the side chain are known as effective inhibitors of androgen signaling and/or testosterone biosynthesis, thus showing beneficial effects for the treatment of prostate cancer. In this work, a series o
Externí odkaz:
https://doaj.org/article/4e84367915094193ad6c9a7604d30bcf
Autor:
Pavel V. Ershov, Alexander V. Veselovsky, Yuri V. Mezentsev, Evgeniy O. Yablokov, Leonid A. Kaluzhskiy, Anastasiya M. Tumilovich, Anton A. Kavaleuski, Andrei A. Gilep, Taisiya V. Moskovkina, Alexei E. Medvedev, Alexis S. Ivanov
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7605 (2020)
Isatin (indole-2, 3-dione) is a non-peptide endogenous bioregulator exhibiting a wide spectrum of biological activity, realized in the cell via interactions with numerous isatin-binding proteins, their complexes, and (sub) interactomes. There is incr
Externí odkaz:
https://doaj.org/article/de1da341bf0d4f15b7246e5fcd4b4a3f
Autor:
A. M. Tumilovich, Andrey Gilep, Anton Kavaleuski, P V Ershov, Andrew Ivanov, E O Yablokov, L. A. Kaluzhskiy, Natallia Strushkevich, Oksana Gnedenko
Publikováno v:
Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology. 15:89-96
Protein–protein interactions (PPIs) are crucial for the successful realization of many metabolic and signaling pathways. Of particular interest are PPIs of membrane proteins, which form stable and/or transient complexes for the signal transduction,
Autor:
Anastasia M. Tumilovich, Sergey A. Usanov, I. V. Haidukevich, A. A. Gilep, Irina Grabovec, T. A. Sushko
Publikováno v:
Toxicology in Vitro. 50:249-256
CYP2C9 plays a major role in drug metabolism. It is highly polymorphic and among the variants, CYP2C9*2 and CYP2C9*3 have been known to encode the protein with moderately to markedly reduced catalytic activity. Azole antifungals are among the most fr
Autor:
Tatsiana Varaksa, A. M. Tumilovich, Ya. V. Dichenko, T. V. Shkel, Anton Kavaleuski, A. A. Gilep, T. S. Cherkesova, I. P. Grabovets, A. V. Vasilevskaya
Publikováno v:
Proceedings of the National Academy of Sciences of Belarus, Chemical Series. 54:190-196
Publikováno v:
Doklady of the National Academy of Sciences of Belarus. 62:170-177
Autor:
A. S. Ivanov, Alexander V. Veselovsky, Evgeniy Yablokov, Anton Kavaleuski, Alexei Medvedev, Taisiya V. Moskovkina, Andrei A. Gilep, Yuri Mezentsev, P V Ershov, Anastasiya M. Tumilovich, L. A. Kaluzhskiy
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7605, p 7605 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 20
International Journal of Molecular Sciences
Volume 21
Issue 20
Isatin (indole-2, 3-dione) is a non-peptide endogenous bioregulator exhibiting a wide spectrum of biological activity, realized in the cell via interactions with numerous isatin-binding proteins, their complexes, and (sub) interactomes. There is incr
Autor:
A. M. Tumilovich, A.Yu. Karputs, A. Ya. Luschik, L. A. Kaluzhskiy, E O Yablokov, P. V. Ershov, Yu. V. Mezentsev, Andrey Gilep, А.S. Ivanov
Publikováno v:
Biomedical Chemistry: Research and Methods. 3:e00134
The study of the effect of low-molecular-weight compounds (substrates, endogenous metabolites, drugs and xenobiotics) on the kinetic and equilibrium parameters of functionally significant binary protein-protein interactions (PPIs) is of both fundamen