Zobrazeno 1 - 10
of 13
pro vyhledávání: '"A. M. Stijnen"'
Autor:
M. Stijnen
Publikováno v:
Studies over de sociaaleconomische geschiedenis van Limburg/Jaarboek van het Sociaal Historisch Centrum voor Limburg. 35:82-139
De aard van de criminaliteit en haar omvang verschilden in de Mijnstreek lange tijd scherp van die in de rest van Nederland. Het verschijnsel heeft onderzoekers al sedert een halve eeuw beziggehouden. Een sluitende verklaring is nog niet gevonden. St
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34300a55c9afbf87cf5bdeb7642d0e1f
https://doi.org/10.58484/ssegl.v35i12709
https://doi.org/10.58484/ssegl.v35i12709
Publikováno v:
Cardiovascular Research. 118
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): ZonMW Introduction Cardiovascular diseases (CVD) are the leading cause of death globally. The CVD that causes most of the deaths annua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b87230f03c4695deea2e2a6ce0a5fccc
https://doi.org/10.1093/cvr/cvac066.037
https://doi.org/10.1093/cvr/cvac066.037
Autor:
M. W. E. Langemeijer, A. Hoogerkamp, S. Hovinga, Meindert Danhof, van Bezooijen Cf, A. M. Stijnen
Publikováno v:
Pharmaceutical Research. 10:1046-1051
The aim of the present investigations was to study the influence of increasing age on the pharmacodynamics of valproate in BN/BiRij rats, applying a threshold for electrically induced localized seizure activity as a measure of the anticonvulsant effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f07a7b8ac5fbae7219bb360a38f4d1a
https://doi.org/10.1023/a:1018975025417
https://doi.org/10.1023/a:1018975025417
Publikováno v:
Pharmaceutical Research. :1456-1459
In a previous study, an apparent age-related increase in brain sensitivity to the anesthetic effect of phenobarbital was observed in BN/BiRij rats. However, since this study was conducted according to a cross-sectional design, the observed change cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2fb43aa98bdd8280999871e4c97939f
https://doi.org/10.1023/a:1015815014166
https://doi.org/10.1023/a:1015815014166
Publikováno v:
Pharmaceutical research. 10(7)
The aim of the present investigations was to study the influence of increasing age on the pharmacodynamics of valproate in BN/BiRij rats, applying a threshold for electrically induced localized seizure activity as a measure of the anticonvulsant effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95c39214743d07f4800fb5320bf0a1b3
https://pubmed.ncbi.nlm.nih.gov/8378246
https://pubmed.ncbi.nlm.nih.gov/8378246
Publikováno v:
Pharmaceutical research. 9(11)
In a previous study, an apparent age-related increase in brain sensitivity to the anesthetic effect of phenobarbital was observed in BN/BiRij rats. However, since this study was conducted according to a cross-sectional design, the observed change cou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::254eee154c1548e7975e9c99c1b81801
https://pubmed.ncbi.nlm.nih.gov/1475233
https://pubmed.ncbi.nlm.nih.gov/1475233
Autor:
Ineke Postel-Westra, Meindert Danhof, M. W. E. Langemeijer, A. Hoogerkamp, Annemiek M. Stijnen, Cornelis F.A. van Bezooijen, Rob A. Voskuyl
1. The purpose of this investigation was to examine the influence of increasing age on the pharmacokinetics and the time course of the anticonvulsant response of oxazepam in BN/BiRij rats as an animal model of aging. 2. Oxazepam was administered intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9750eb427527a3f19b67381a1ec20ccc
https://europepmc.org/articles/PMC1907588/
https://europepmc.org/articles/PMC1907588/
Autor:
C. F. A. Van Bezooijen, S. Hovinga, Meindert Danhof, A. M. Stijnen, Jaap W. Mandema, M. W. E. Langemeijer
1. The purpose of the present investigations was to determine the influence of increasing age on the pharmacokinetics and pharmacodynamics of midazolam in male BN/BiRij rats as an animal model of aging. 2. Midazolam was administered intravenously at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4d138c04c896247f10019522715953
https://europepmc.org/articles/PMC1907602/
https://europepmc.org/articles/PMC1907602/
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 261(1)
The purpose of this study was to determine the influence of age on the pharmacokinetic/pharmacodynamic relationship of phenobarbital in male BN/BiRij rats aged 4, 15, 26, 31 and 36 months. The pharmacokinetics were studied on basis of the plasma conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f9bfef8fb63fb5b403dcaa82dcb59afd
https://pubmed.ncbi.nlm.nih.gov/1560386
https://pubmed.ncbi.nlm.nih.gov/1560386
Autor:
R.A.M. van der Hoeven, J. van der Greef, Wilfried M. A. Niessen, A. M. Stijnen, Meindert Danhof, C. E. M. Heeremans
Publikováno v:
Journal of chromatography. 554(1-2)
An unknown heptabarbital metabolite, observed in the liquid chromatogram of rat plasma and urine samples after administration of heptabarbital, was identified by liquid chromatography-thermospray tandem mass spectrometry. By applying the parent scan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9553cdaf4bbad3c2bda827307d7b6f
https://pubmed.ncbi.nlm.nih.gov/1686611
https://pubmed.ncbi.nlm.nih.gov/1686611