Zobrazeno 1 - 10
of 106
pro vyhledávání: '"A. M. Staffaroni"'
Autor:
F. M. Elahi, D. Harvey, M. Altendahl, N. Brathaban, N. Fernandes, K. B. Casaletto, A. M. Staffaroni, P. Maillard, J. D. Hinman, B. L. Miller, C. DeCarli, J. H. Kramer, E. J. Goetzl
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract We test the hypothesis that endothelial cells adopt an inflammatory phenotype in functionally intact aged human subjects with radiographic evidence of white matter hyperintensity (WMH) suggestive of small cerebrovascular disease. Components
Externí odkaz:
https://doaj.org/article/c2b0d26e6a324690b574d146c5796722
Autor:
Breton M. Asken, Jessica M. Bove, Russell M. Bauer, Jeremy A. Tanner, Kaitlin B. Casaletto, Adam M. Staffaroni, Lawren VandeVrede, Michael L. Alosco, Jesse B. Mez, Robert A. Stern, Bruce L. Miller, Lea T. Grinberg, Adam L. Boxer, Maria Luisa Gorno-Tempini, Howie J. Rosen, Gil D. Rabinovici, Joel H. Kramer
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Background Traumatic brain injury (TBI) and repetitive head impacts (RHI) have been linked to increased risk for multiple types of neurodegenerative disease, higher dementia risk, and earlier age of dementia symptom onset, suggesting transdi
Externí odkaz:
https://doaj.org/article/e6317e81cad640f78dcc0f579d63519a
Autor:
Emily W Paolillo, Kaitlin B Casaletto, Annie L Clark, Jack C Taylor, Hilary W Heuer, Amy B Wise, Sreya Dhanam, Mark Sanderson-Cimino, Rowan Saloner, Joel H Kramer, John Kornak, Walter Kremers, Leah Forsberg, Brian Appleby, Ece Bayram, Andrea Bozoki, Danielle Brushaber, R Ryan Darby, Gregory S Day, Bradford C Dickerson, Kimiko Domoto-Reilly, Fanny Elahi, Julie A Fields, Nupur Ghoshal, Neill Graff-Radford, Matthew G H Hall, Lawrence S Honig, Edward D Huey, Maria I Lapid, Irene Litvan, Ian R Mackenzie, Joseph C Masdeu, Mario F Mendez, Carly Mester, Toji Miyagawa, Georges Naasan, Belen Pascual, Peter Pressman, Eliana Marisa Ramos, Katherine P Rankin, Jessica Rexach, Julio C Rojas, Lawren VandeVrede, Bonnie Wong, Zbigniew K Wszolek, Bradley F Boeve, Howard J Rosen, Adam L Boxer, Adam M Staffaroni
Publikováno v:
JMIR Aging, Vol 7, p e52831 (2024)
BackgroundFrontotemporal lobar degeneration (FTLD) is a leading cause of dementia in individuals aged
Externí odkaz:
https://doaj.org/article/e3a85b9c842b435281a2a70b74fac8bf
Autor:
Breton M. Asken, Jeremy A. Tanner, Leslie S. Gaynor, Lawren VandeVrede, William G. Mantyh, Kaitlin B. Casaletto, Adam M. Staffaroni, Corrina Fonseca, Ranjani Shankar, Harli Grant, Karen Smith, Argentina Lario Lago, Haiyan Xu, Renaud La Joie, Yann Cobigo, Howie Rosen, David C. Perry, Julio C. Rojas, Bruce L. Miller, Raquel C. Gardner, Kevin K. W. Wang, Joel H. Kramer, Gil D. Rabinovici
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-12 (2023)
Abstract Background Traumatic encephalopathy syndrome (TES) is a clinical phenotype sensitive but non-specific to underlying chronic traumatic encephalopathy (CTE) neuropathology. However, cognitive symptoms of TES overlap with Alzheimer’s disease
Externí odkaz:
https://doaj.org/article/339b6a4d0f624fd8b1dc8af195d378b2
Autor:
Jack Carson Taylor, Hilary W. Heuer, Annie L. Clark, Amy B. Wise, Masood Manoochehri, Leah Forsberg, Carly Mester, Meghana Rao, Daniell Brushaber, Joel Kramer, Ariane E. Welch, John Kornak, Walter Kremers, Brian Appleby, Bradford C. Dickerson, Kimiko Domoto‐Reilly, Julie A. Fields, Nupur Ghoshal, Neill Graff‐Radford, Murray Grossman, Matthew GH Hall, Edward D. Huey, David Irwin, Maria I. Lapid, Irene Litvan, Ian R. Mackenzie, Joseph C. Masdeu, Mario F. Mendez, Naomi Nevler, Chiadi U. Onyike, Belen Pascual, Peter Pressman, Katherine P. Rankin, Buddhika Ratnasiri, Julio C. Rojas, Maria Carmela Tartaglia, Bonnie Wong, Maria Luisa Gorno‐Tempini, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer, Adam M. Staffaroni
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 2, Pp n/a-n/a (2023)
Abstract Introduction Remote smartphone assessments of cognition, speech/language, and motor functioning in frontotemporal dementia (FTD) could enable decentralized clinical trials and improve access to research. We studied the feasibility and accept
Externí odkaz:
https://doaj.org/article/ddb1152f42564be09bd4bebba08f13f1
Autor:
Yann Cobigo, Matthew S. Goh, Amy Wolf, Adam M. Staffaroni, John Kornak, Bruce L. Miller, Gil D. Rabinovici, William W. Seeley, Salvatore Spina, Adam L. Boxer, Bradley F. Boeve, Lei Wang, Ricardo Allegri, Marty Farlow, Hiroshi Mori, Richard J. Perrin, Joel Kramer, Howard J. Rosen
Publikováno v:
NeuroImage: Clinical, Vol 36, Iss , Pp 103144- (2022)
Early detection of neurodegeneration, and prediction of when neurodegenerative diseases will lead to symptoms, are critical for developing and initiating disease modifying treatments for these disorders. While each neurodegenerative disease has a typ
Externí odkaz:
https://doaj.org/article/90396126c3e54919aa17c885d268e751
Autor:
Adam M. Staffaroni, Sandra Weintraub, Katya Rascovsky, Katherine P. Rankin, Jack Taylor, Julie A. Fields, Kaitlin B. Casaletto, Argye E. Hillis, Sladjana Lukic, Maria Luisa Gorno‐Tempini, Hilary Heuer, Merilee A. Teylan, Walter A. Kukull, Bruce L. Miller, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer, Joel H. Kramer
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction The Frontotemporal Lobar Degeneration Module (FTLD‐MOD) includes a neuropsychological battery designed to assess the clinical features of FTLD, although much is unknown about its utility. We investigated FTLD‐MOD and Uniform
Externí odkaz:
https://doaj.org/article/187ece54033d4d8e953d8c37dcbca237
Autor:
Fanny M. Elahi, Senyo B. Ashimatey, Daniel J. Bennett, Samantha M. Walters, Renaud La Joie, Xuejuan Jiang, Amy Wolf, Yann Cobigo, Adam M. Staffaroni, Howie J. Rosen, Bruce L. Miller, Gil D. Rabinovici, Joel H. Kramer, Ari J. Green, Amir H. Kashani
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Apolipoprotein E (APOE) ε4, the strongest non‐Mendelian genetic risk factor for Alzheimer's disease (AD), has been shown to affect brain capillaries in mice, with potential implications for AD‐related neurodegenerative dise
Externí odkaz:
https://doaj.org/article/5e77403b65c248119d5316b55523d5ed
Autor:
Ophir Keret, Adam M. Staffaroni, John M. Ringman, Yann Cobigo, Sheng‐Yang M. Goh, Amy Wolf, Isabel Elaine Allen, Stephen Salloway, Jasmeer Chhatwal, Adam M. Brickman, Dolly Reyes‐Dumeyer, Randal J. Bateman, Tammie L.S. Benzinger, John C. Morris, Beau M. Ances, Nelly Joseph‐Mathurin, Richard J. Perrin, Brian A. Gordon, Johannes Levin, Jonathan Vöglein, Mathias Jucker, Christian laFougère, Ralph N. Martins, Hamid R. Sohrabi, Kevin Taddei, Victor L. Villemagne, Peter R. Schofield, William S. Brooks, Michael Fulham, Colin L. Masters, Bernardino Ghetti, Andrew J. Saykin, Clifford R. Jack, Neill R. Graff‐Radford, Michael Weiner, David M. Cash, Ricardo F. Allegri, Patricio Chrem, Su Yi, Bruce L. Miller, Gil D. Rabinovici, Howard J. Rosen, Dominantly Inherited Alzheimer Network
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Asymptomatic and mildly symptomatic dominantly inherited Alzheimer's disease mutation carriers (DIAD‐MC) are ideal candidates for preventative treatment trials aimed at delaying or preventing dementia onset. Brain atrophy is a
Externí odkaz:
https://doaj.org/article/90049bc6e3de456c9fce7e852de2612b
Autor:
Sabrina J. Erlhoff, Michelle You, Molly E. Zimmerman, Sladjana Lukic, Adam M. Staffaroni, Gil D. Rabinovici, Kaitlin B. Casaletto, Katherine L. Possin, Jordan Stiver, Renaud La Joie, Samantha M Walters, Joel H. Kramer, Maria Luisa Gorno-Tempini
Publikováno v:
The Clinical neuropsychologist. 36(7)
Progressive word-finding difficulty is a primary cognitive complaint among healthy older adults and a symptom of pathological aging. Classic measures of visual confrontation naming, however, show c...