Chemical Adjustment of Fibrinolysis

Autor: Alexey M. Shibeko, Ivan S. Ilin, Nadezhda A. Podoplelova, Vladimir B. Sulimov, Mikhail A. Panteleev

Publikováno v: Pharmaceuticals, Vol 17, Iss 1, p 92 (2024)

Fibrinolysis is the process of the fibrin–platelet clot dissolution initiated after bleeding has been stopped. It is regulated by a cascade of proteolytic enzymes with plasmin at its core. In pathological cases, the balance of normal clot formation

Externí odkaz: https://doaj.org/article/af2cbd7b84a74baea03b464eba699b70

An enhanced clot growth rate before in vitro fertilization decreases the probability of pregnancy.

Autor: A N Balandina, E M Koltsova, T A Teterina, A G Yakovenko, E U Simonenko, A V Poletaev, I V Zorina, A M Shibeko, T A Vuimo, S A Yakovenko, F I Ataullakhanov

Publikováno v: PLoS ONE, Vol 14, Iss 5, p e0216724 (2019)

BACKGROUND:The shift towards hypercoagulation during in vitro fertilization (IVF) can lead to the impairment of embryo implantation and placental blood circulation, which is believed to be a factor in an unsuccessful IVF cycle. OBJECTIVES:To assess c

Externí odkaz: https://doaj.org/article/48eb47e427004e1bb66d39f22002a536

Thrombogenic potential of picomolar coagulation factor XIa is mediated by thrombin wave propagation

Autor: Leonid A Parunov, Yideng Liang, Qijin Lu, Alexey M Shibeko, Erik I. Tucker, Timothy K. Lee, Fazoil I Ataullakhanov, Dorothy Scott, Mikhail V Ovanesov

Publikováno v: Blood Advances.

Inhibitors of coagulation factor (F) XIa are currently investigated as potential anticoagulant therapies. We hypothesized that circulating FXIa may be a potential target for these therapies. Using previous analyses of FXIa impurity in immune globulin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25761cdb087100a2c10a3455f6660c82
https://doi.org/10.1182/bloodadvances.2022008743

Co-ordinated spatial propagation of blood plasma clotting and fibrinolytic fronts.

Autor: Ansar S Zhalyalov, Mikhail A Panteleev, Marina A Gracheva, Fazoil I Ataullakhanov, Alexey M Shibeko

Publikováno v: PLoS ONE, Vol 12, Iss 7, p e0180668 (2017)

Fibrinolysis is a cascade of proteolytic reactions occurring in blood and soft tissues, which functions to disintegrate fibrin clots when they are no more needed. In order to elucidate its regulation in space and time, fibrinolysis was investigated u

Externí odkaz: https://doaj.org/article/a3e4d40611cc4abf8c447a1dfe9a04c9

Quantitative 3D analysis of tissue damage in a rat model of microembolization

Autor: Anushree Dwivedi, Francesco Migliavacca, Simon F. De Meyer, Nerea Arrarte Terreros, Vanessa Blanc-Guillemaud, Stephen J. Payne, Ed van Bavel, Sarah Vandelanotte, Tamás I. Józsa, Ray McCarthy, Praneeta R Konduri, Gabriele Dubini, Jose Felix Rodriguez Matas, Aad van der Lugt, H.F. Lingsma, Diederik W.J. Dippel, Raymond M. Padmos, Ybwem (Yvo) Roos, Bastien Chopard, Henk A. Marquering, Ed VanBavel, A. M. Shibeko, Giulia Luraghi, Patrick Mc Garry, Mikhail A. Panteleev, Sissy Georgakopoulou, Sara Bridio, Kevin M. Moerman, Sharon Duffy, Michael Gilvarry, Charles B. L. M. Majoie, Victor Azizi, Noor Samuels, Franck Raynaud, Nikki Boodt, Remy Petkantchin, Senna Staessens, Theodosia Georgakopoulou, Claire Miller, Karim Zouaoui Boudjeltia, Max van der Kolk, Behrooz Fereidoonnezhad, Erik N. T. P. Bakker, Alfons G. Hoekstra, Anne Eva van der Wijk

Publikováno v: Journal of biomechanics, 128:110723. Elsevier Limited
Journal of Biomechanics, 128:110723. Elsevier Ltd.
Journal of Biomechanics, 128:110723. Elsevier
Journal of Biomechanics, 128:110723. Elsevier Limited
NARCIS
ORCID
Microsoft Academic Graph

There is a discrepancy between successful recanalization and good clinical outcome after endovascular treatment (EVT) in acute ischemic stroke patients. During removal of a thrombus, a shower of microemboli may release and lodge to the distal circula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb0da97e38e7e5b511ea60b581bbb48
https://pure.amc.nl/en/publications/quantitative-3d-analysis-of-tissue-damage-in-a-rat-model-of-microembolization(ed81f25c-d747-4f7c-af72-e57e02b9d863).html