Zobrazeno 1 - 10
of 51
pro vyhledávání: '"A. M. Ryvkin"'
Publikováno v:
Journal of Evolutionary Biochemistry and Physiology. 58:S125-S133
Autor:
D. O Balakhnov, N. V Belyankina, V. P Butikov, I. S Kovalev, M. M Matyukhina, V. M Ryvkin, E. A Kholod, T. V Chesnakova, N. V Shishova
Publikováno v:
КардиоСоматика, Vol 6, Iss 1-1 (2015)
Лечение пациентов с миокардитами, в том числе неревматической этиологии, определено стандартами медицинской помощи и порядками оказан
Externí odkaz:
https://doaj.org/article/4f656965e971484f87ca839f7b411cae
Autor:
A. M. Ryvkin, Nikita Markov
Publikováno v:
2020 Ural Symposium on Biomedical Engineering, Radioelectronics and Information Technology (USBEREIT).
Intracellular calcium plays a major role in the electromechanical coupling in cardiac venrticular cells and in the action potential formation process in heart pacemaker cells. Calcium sparks are elementary events of the calcium release from sarcoplas
Autor:
E. A. Budeeva, A. M. Ryvkin
Publikováno v:
Mathematical Analysis With Applications ISBN: 9783030421755
A regular rhythm of the mechanical contraction of the heart is formed in the so-called sinoatrial node (SAN) of the heart. In the current paper we introduce a mathematical model of the SAN cell functionality paying particular attention to calcium act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db0b5619eb1f9f0a0468d2fcba2e8943
https://doi.org/10.1007/978-3-030-42176-2_29
https://doi.org/10.1007/978-3-030-42176-2_29
Autor:
Nikita Markov, A. M. Ryvkin
Publikováno v:
2019 Ural Symposium on Biomedical Engineering, Radioelectronics and Information Technology (USBEREIT).
Here we introduce the results of the computer simulations on the study of age-associated abnormalities of the Ca2+ release unit functioning in the sinoatrial node cells. We simulated the decrease of sarco/endoplasmic reticulum Ca2+- ATPase activity a
Autor:
A. M. Ryvkin, Nikita Markov
Publikováno v:
CinC
Here we introduce results of a mathematical modeling of calcium sparks in cardiac cells. We developed a model of the calcium release unit which includes a single sarcoplasmic reticulum (SR) lumen, a regular 9×9 cluster of RyRs and a dyadic space. 2D
Autor:
Anastasia Khokhlova, A. S. Moskvin, Vladimir A. Golovko, Olga Solovyova, R. A. Syunyaev, A. M. Ryvkin, R. R. Aliev, D. V. Shmarko, Mikhail Gonotkov, E. A. Lebedeva
Publikováno v:
Biophysics. 61:893-900
We studied the effects of intracellular calcium dynamics on the spontaneous activity of the pacemaker cells using mathematical modeling. We compared the responses to the suppression of L-type calcium currents in several models of the electrical activ
Publikováno v:
Biophysics. 61:614-621
The temperature effect on cardiac ryanodine receptor (RyR) function has been studied within the electron-conformational (EC) model. It’s shown that a simple EC model with an Arrhenius-like temperature dependence of the “internal” and “externa
Autor:
Nikita Markov, A. M. Ryvkin
Publikováno v:
2018 Ural Symposium on Biomedical Engineering, Radioelectronics and Information Technology (USBEREIT).
Spontaneous local calcium releases (sparks) from sarcoplasmic reticulum (SR) in heart cell were modeled. We solved two-dimensional problem of Ca2+ diffusion along the dyadic space and “domino-like” activation of ryanodine receptors (RyRs) on the
Publikováno v:
Biophysics. 60:946-952
An integrative model of the calcium dynamics in cardiac pacemaker cells is developed taking into account a synergetic effect of the interaction between an outer membrane oscillator and an intracellular calcium oscillator ("membrane and Ca(2+)-clock")