Výsledky vyhledávání - "A. M. Ratmirov"

Hippocampal Neurogenesis, Dopaminergic Neurons of the Substantia Nigra, and Behavior after Intranasal Administration of Native α-Synuclein Protein to Ageing Mice

Autor: E. V. Konovalova, Vladimir V. Sherstnev, Marina A. Gruden, O. A. Solov’eva, A. M. Ratmirov

Publikováno v: Neurochemical Journal. 15:71-78

—We studied the effects of intranasal administration of native α-synuclein, whose hyperproduction and misfolding are the key link in the pathogenesis of Parkinson’s disease and other age-related neurodegenerative diseases, on hippocampal neuroge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::40ee0097e9f8ca09d2f160fddb58f642
https://doi.org/10.1134/s181971242101013x

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Effects of antibodies to glutamate on cerebral expression of the Tnfrsf1A gene under conditions of spatial amnesia induced by proinflammatory protein S100A9 fibrils in aging mice

Autor: Davydova Tv, Marina A. Gruden, Robert David Edmund Sewell, A M Ratmirov

Proinflammatory S100A9 protein is a promoter of inflammation-linked neurodegeneration and the Tnfrsf1A gene encodes the TNF receptor 1A that binds TNFα to function as a regulator of inflammation. We studied the effects of chronic intranasal administ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71b1b3929a493eecfee6f1f9f0fb5d0e

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Effects of Antibodies to Glutamate on Cerebral Expression of the Tnfrsf1A Gene under Conditions of Spatial Amnesia Induced by Proinflammatory Protein S100A9 Fibrils in Aging Mice

Autor: M A, Gruden, T V, Davydova, A M, Ratmirov, R D E, Sewell

Publikováno v: Bulletin of experimental biology and medicine. 172(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::02facfbf58ed0d9b6ed36a401ed7d2e8
https://pubmed.ncbi.nlm.nih.gov/34796426

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The Effects of Fibrillar Forms of α-Synuclein Protein on Neurogenesis in the Hippocampus, Dopaminergic Neurons of the Substantia Nigra, and the Behavior of Ageing Mice

Autor: E. V. Konovalova, A. V. Kedrov, O. A. Solov’eva, Vladimir V. Sherstnev, Marina A. Gruden, A. M. Ratmirov

Publikováno v: Neurochemical Journal. 12:359-365

Hyperproduction and disturbance of the protein conformation of α-synuclein that are associated with the formation of aggregated forms, which have a neurotoxic effect, are the key link in the mechanisms of the pathogenesis of synucleinopathies, which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ec1db900e113bb0f309a77dbda58456
https://doi.org/10.1134/s1819712418040062

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The Neurogenesis Actuator and NR2B/NMDA Receptor Antagonist Ro25-6981 Consistently Improves Spatial Memory Retraining Via Brain Region-Specific Gene Expression

Autor: Marina A. Gruden, Robert David Edmund Sewell, Olga Solovieva, Zinaida I. Storozheva, Vladimir V. Sherstnev, Alexander M. Ratmirov

Publikováno v: Journal of Molecular Neuroscience

NR2B-containing NMDA (NR2B/NMDA) receptors are important in controlling neurogenesis and are involved in generating spatial memory. Ro25-6981 is a selective antagonist at these receptors and actuates neurogenesis and spatial memory. Inter-structural

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7617d15aa2681bccbce4b2606e732cea
https://doi.org/10.1007/s12031-018-1083-5

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Pattern of Notch2, Numb, and Cas8 Gene Expression in Relevant Structures of the Rat Brain during Formation of Spatial Memory

Autor: Z. I. Storozheva, Vladimir V. Sherstnev, A. M. Ratmirov, Marina A. Gruden

Publikováno v: Bulletin of Experimental Biology and Medicine. 163:785-788

The expression of Notch2, Numb, and Cas8 genes, whose protein products are involved in regulation of neurogenesis/neuroapoptosis processes, was studied in the relevant cerebral structures of male Wistar rats trained in a spatial habit. The formation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bd41c80d84e2273a85e6bc96046ea76
https://doi.org/10.1007/s10517-017-3903-y

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