Zobrazeno 1 - 10
of 185
pro vyhledávání: '"A. M. Nadtochiy"'
Autor:
Caio Tabata Fukushima, Ian-Shika Dancil, Hannah Clary, Nidhi Shah, Sergiy M. Nadtochiy, Paul S. Brookes
Publikováno v:
Redox Biology, Vol 70, Iss , Pp 103047- (2024)
Ischemic tissues accumulate succinate, which is rapidly oxidized upon reperfusion, driving a burst of mitochondrial reactive oxygen species (ROS) generation that triggers cell death. In isolated mitochondria with succinate as the sole metabolic subst
Externí odkaz:
https://doaj.org/article/a660219d5cd04eae9638469880173663
Autor:
Gisela Beutner, Jonathan Ryan Burris, Michael P. Collins, Chaitanya A. Kulkarni, Sergiy M. Nadtochiy, Karen L. de Mesy Bentley, Ethan D. Cohen, Paul S. Brookes, George A. Porter, Jr.
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109157- (2024)
Summary: In the embryonic heart, the activation of the mitochondrial electron transport chain (ETC) coincides with the closure of the cyclophilin D (CypD) regulated mitochondrial permeability transition pore (mPTP). However, it remains to be establis
Externí odkaz:
https://doaj.org/article/a462e368f5ea459999c5d9156d652a7f
Autor:
Vladislav V. Andryushkin, Anna S. Dragunova, Sergey D. Komarov, Alexey M. Nadtochiy, Andrey G. Gladyshev, Andrey V. Babichev, Alexander V. Uvarov, Innokenty I. Novikov, Evgenii S. Kolodeznyi, Leonid Ya. Karachinsky, Natalia V. Kryzhanovskaya, Vladimir N. Nevedomskii, Anton Yu. Egorov, Vladislav E. Bougrov
Publikováno v:
Naučno-tehničeskij Vestnik Informacionnyh Tehnologij, Mehaniki i Optiki, Vol 22, Iss 5, Pp 921-928 (2022)
The results of the study of the optical properties of low-density InGaPAs quantum dots, as well as the effect of low temperatures and thermal annealing parameters on their optical and structural properties were presented. InGaPAs quantum dots were fo
Externí odkaz:
https://doaj.org/article/767f65f8e2974eb19d57bbb18aeb31cf
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 13 (2022)
Background The metabolite succinate accumulates during cardiac ischemia. Within 5 minutes of reperfusion, succinate returns to baseline levels via both its release from cells and oxidation by mitochondrial complex II. The latter drives reactive oxyge
Externí odkaz:
https://doaj.org/article/9215f15c122a41b89f7364e581557029
Autor:
Sergiy M. Nadtochiy, Tatsiana Stefanos, Ronald E. Angona, Nathan Darrow, C.C.P., Karen Jones, Changyong Feng, Mohamed Algahim, Dana LeMoine, Robin Westcott, Brian Anderson, Michael F. Swartz, Michael P. Eaton
Publikováno v:
Anesthesiology. 138:523-532
Background Heparin anticoagulation has been used successfully for cardiopulmonary bypass (CPB). However, an alternative anticoagulant approach is desirable due to the cases of heparin-induced thrombocytopenia. Dabigatran provides anticoagulation for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd9753e789e66b180f3a4b9b8c251f98
https://doi.org/10.1097/aln.0000000000004537
https://doi.org/10.1097/aln.0000000000004537
Autor:
Alexey E. Zhukov, Eduard I. Moiseev, Alexey M. Nadtochiy, Nikita A. Fominykh, Konstantin A. Ivanov, Ivan S. Makhov, Mikhail V. Maximov, Fedor I. Zubov, Vladimir G. Dubrovskii, Sergey A. Mintairov, Nikolay A. Kalyuzhnyy, Nikita Yu Gordeev, Yuri M. Shernyakov, Natalia V. Kryzhanovskaya
Publikováno v:
IEEE Journal of Quantum Electronics. 59:1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfff67064d86d122f36770b34d687b37
https://doi.org/10.1109/jqe.2022.3229300
https://doi.org/10.1109/jqe.2022.3229300
Publikováno v:
Journal of Molecular and Cellular Cardiology. 174:101-114
Tissue ischemia results in intracellular pH (pHIN) acidification, and while accumulation of metabolites such as lactate is a known driver of acidic pHIN, less is known about how acidic pHIN regulates metabolism. Furthermore, acidic extracellular (pHE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d442ee7a304cd1945940ef2f4df9da
https://doi.org/10.1016/j.yjmcc.2022.11.008
https://doi.org/10.1016/j.yjmcc.2022.11.008
Autor:
Chaitanya A Kulkarni, Sergiy M Nadtochiy, Leslie Kennedy, Jimmy Zhang, Sophea Chhim, Hanan Alwaseem, Elizabeth Murphy, Dragony Fu, Paul S Brookes
Publikováno v:
eLife, Vol 9 (2020)
Alkb homolog 7 (ALKBH7) is a mitochondrial α-ketoglutarate dioxygenase required for DNA alkylation-induced necrosis, but its function and substrates remain unclear. Herein, we show ALKBH7 regulates dialdehyde metabolism, which impacts the cardiac re
Externí odkaz:
https://doaj.org/article/0dc515db99d74ef0bd80e3abdb1bbe69
Publikováno v:
Pediatric Anesthesia. 32:1113-1120
Dabigatran is an anticoagulant with potential use during cardiopulmonary bypass in children and adults. The pharmacokinetic-pharmacodynamic relationship for dabigatran anticoagulation effect was investigated in an intact animal model using rabbits.Te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9419f8a47bcaf427678822cc9240f101
https://doi.org/10.1111/pan.14511
https://doi.org/10.1111/pan.14511
Autor:
A. A. Kharchenko, A. M. Nadtochiy, A. A. Serin, S. A. Mintairov, N. A. Kalyuzhnyy, A. E. Zhukov, M. V. Maximov, S. Breuer
Publikováno v:
Semiconductors. 56:329-332
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1db357d16ed8da5fb4e8135033bde93d
https://doi.org/10.1134/s106378262207003x
https://doi.org/10.1134/s106378262207003x