Výsledky vyhledávání - "A. M. Mwinzi"

Akademický článek

Absence of lower genital tract lesions among women of reproductive age infected with Schistosoma mansoni: A cross-sectional study using a colposcope in Western Kenya.

Autor: Huldah C Sang, Pauline N M Mwinzi, Maurice R Odiere, Isaac Onkanga, Fredrick Rawago, Pavitra Pillay, Eyrun Floerecke Kjetland

Publikováno v: PLoS Neglected Tropical Diseases, Vol 16, Iss 7, p e0010473 (2022)

BackgroundFemale genital schistosomiasis (FGS) constitutes four different lesions known to be caused by Schistosoma haematobium ova deposited in the genital tract. Schistosoma mansoni ova may also be found in the genital tract. However, it is not kno

Externí odkaz: https://doaj.org/article/3f38d254d9b94d7ca2957bcd1fd7b2bf

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Akademický článek

Unprotected water sources and low latrine coverage are contributing factors to persistent hotspots for schistosomiasis in western Kenya.

Autor: Rosemary M Musuva, Maurice R Odiere, Pauline N M Mwinzi, Isaiah O Omondi, Fredrick O Rawago, Sultani H Matendechero, Nupur Kittur, Carl H Campbell, Daniel G Colley

Publikováno v: PLoS ONE, Vol 16, Iss 9, p e0253115 (2021)

BackgroundEvidence indicates that whereas repeated rounds of mass drug administration (MDA) programs have reduced schistosomiasis prevalence to appreciable levels in some communities referred to here as responding villages (R). However, prevalence ha

Externí odkaz: https://doaj.org/article/fb96bc82fe4548f68b8991f2e16c5452

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Akademický článek

Protocol and baseline data for a multi-year cohort study of the effects of different mass drug treatment approaches on functional morbidities from schistosomiasis in four African countries

Publikováno v: BMC Infectious Diseases, Vol 17, Iss 1, Pp 1-11 (2017)

Abstract Background The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) focus is on randomized trials of different approaches to mass drug administration (MDA) in endemic countries in Africa. Because their studies provided

Externí odkaz: https://doaj.org/article/65edcd9ebdb9449780153fa584733881

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Effect of preventive chemotherapy with praziquantel on schistosomiasis among school-aged children in sub-Saharan Africa: a spatiotemporal modelling study

Publikováno v: The Lancet. Infectious Diseases

Summary Background Over the past 20 years, schistosomiasis control has been scaled up. Preventive chemotherapy with praziquantel is the main intervention. We aimed to assess the effect of preventive chemotherapy on schistosomiasis prevalence in sub-S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c2c3886e862094b62f6badcbd7b388b
https://doi.org/10.1016/s1473-3099(21)00090-6

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Akademický článek

Aberrant plasma MMP and TIMP dynamics in Schistosoma - Immune reconstitution inflammatory syndrome (IRIS).

Autor: Odin Goovaerts, Pauline N M Mwinzi, Erick M O Muok, Ann Ceulemans, Robert Colebunders, Luc Kestens

Publikováno v: PLoS Neglected Tropical Diseases, Vol 12, Iss 8, p e0006710 (2018)

BACKGROUND:Among the different faces of immune reconstitution inflammatory syndrome (IRIS) developing in HIV-patients, no clinical definition has been reported for Schistosomiasis-IRIS (Schisto-IRIS). Although Schisto-IRIS remains largely uninvestiga

Externí odkaz: https://doaj.org/article/1c6e711632d24d4bb38188ae1f705bb6

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Akademický článek

Diet and hygiene practices influence morbidity in schoolchildren living in Schistosomiasis endemic areas along Lake Victoria in Kenya and Tanzania-A cross-sectional study.

Autor: Iman Mohamed, Safari Kinung'hi, Pauline N M Mwinzi, Isaac O Onkanga, Kennedy Andiego, Geoffrey Muchiri, Maurice R Odiere, Birgitte Jyding Vennervald, Annette Olsen

Publikováno v: PLoS Neglected Tropical Diseases, Vol 12, Iss 3, p e0006373 (2018)

Since 2011, cohorts of schoolchildren in regions bordering Lake Victoria in Kenya and Tanzania have been investigated for morbidity caused by Schistosoma mansoni infection. Despite being neighbouring countries with similar lifestyles and ecological e

Externí odkaz: https://doaj.org/article/c8da60be7f724d0d89ea6d14b119a504

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Akademický článek

Cluster randomized trial comparing school-based mass drug administration schedules in areas of western Kenya with moderate initial prevalence of Schistosoma mansoni infections.

Autor: Diana M S Karanja, Emmy K Awino, Ryan E Wiegand, Edward Okoth, Bernard O Abudho, Pauline N M Mwinzi, Susan P Montgomery, W Evan Secor

Publikováno v: PLoS Neglected Tropical Diseases, Vol 11, Iss 10, p e0006033 (2017)

Mass drug administration (MDA) using praziquantel is the WHO-recommended approach for control of schistosomiasis. However, few studies have compared the impact of different schedules of MDA on the resultant infection levels. We wished to evaluate whe

Externí odkaz: https://doaj.org/article/383b2a8cfcb247eaa3d67ca3f4270f48

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Akademický článek

Change in children's school behavior after mass administration of praziquantel for Schistosoma mansoni infection in endemic areas of western Kenya: A pilot study using the Behavioral Assessment System for Children (BASC-2).

Autor: Rosemary Musuva, Ye Shen, Xianjue Wei, Sue Binder, Julianne A Ivy, W Evan Secor, Susan P Montgomery, Charles H King, Pauline N M Mwinzi

Publikováno v: PLoS ONE, Vol 12, Iss 7, p e0181975 (2017)

Schistosomiasis is a parasite-related chronic inflammatory condition that can cause anemia, decreased growth, liver abnormalities, and deficits in cognitive functioning among children.This study used the Behavior Assessment System for Children (BASC-

Externí odkaz: https://doaj.org/article/a7400693fe544e3fb04e9d1f9bcc9409

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Expression of CD117 (c-Kit) on Circulating B Cells in Pediatric Schistosomiasis

Autor: Isaac O. Onkanga, Rachael Hamilton, Pauline N. M. Mwinzi, Thomas Schneider, Bartholomew N. Ondigo, Huldah Sang, Edna Ondari, Fredrick Rawago, Walter Jaoko, Maurice R. Odiere, Lisa Ganley-Leal

Publikováno v: Infect Immun

Few B cells express CD27, the primary marker for memory B cells, in pediatric schistosomiasis, suggesting B cell malfunction. This study further demonstrates unexpected high expression of CD117 on circulating B cells in children highly exposed to Sch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0e00fe4290775e5d8ca77c9a72a7eb3
https://doi.org/10.1128/iai.00160-22

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SCORE Studies on the Impact of Drug Treatment on Morbidity due to Schistosoma mansoni and Schistosoma haematobium Infection

Autor: Rosemary M. Musuva, Pascal Magnussen, Ye Shen, Gisele Nepomuceno de Andrade, Daniel G. Colley, Pauline N. M. Mwinzi, Ryan E. Wiegand, Sue Binder, Christopher C. Whalen, Charles H. King, Safari Kinung’hi, Carl H. Campbell, Susan P. Montgomery, Annette Olsen, Amara E. Ezeamama, William Evan Secor

Publikováno v: The American Journal of Tropical Medicine and Hygiene
King, C H, Binder, S, Shen, Y, Whalen, C C, Campbell, C H, Wiegand, R E, Olsen, A, Secor, W E, Montgomery, S P, Musuva, R, Mwinzi, P N M, Magnussen, P, Kinung'hi, S, Andrade, G N, Ezeamama, A E & Colley, D G 2020, ' SCORE studies on the impact of drug treatment on morbidity due to Schistosoma mansoni and Schistosoma haematobium infection ', American Journal of Tropical Medicine and Hygiene, vol. 103, no. 1_Suppl, pp. 30-35 . https://doi.org/10.4269/ajtmh.19-0830

The Schistosomiasis Consortium for Operational Research (SCORE) was funded in 2008 to improve the evidence base for control and elimination of schistosomiasis—better understanding of the systemic morbidities experienced by children in schistosomias

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b930c0a335a43498d6468cc822ccb1a
http://europepmc.org/articles/PMC7351303

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