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Akademický článek

Re-examining the factor structure of the Insomnia Severity Index (ISI) and defining the meaningful within-individual change (MWIC) for subjects with insomnia disorder in two phase III clinical trials of the efficacy of lemborexant

Autor: William R. Lenderking, Yulia Savva, Mark J. Atkinson, Renee Campbell, Isabelle Chabot, Margaret Moline, Genevieve Meier, Charles M. Morin

Publikováno v: Journal of Patient-Reported Outcomes, Vol 8, Iss 1, Pp 1-12 (2024)

Abstract Background The Insomnia Severity Index (ISI) is a widely used measure of insomnia severity. Various ISI research findings suggest different factor solutions and meaningful within-individual change (MWIC) to detect treatment response in patie

Externí odkaz: https://doaj.org/article/7f9f97c9d0c94205b47b1870f1dab97e

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Akademický článek

Investigating non-inferiority of internet-delivered versus face-to-face cognitive behavioural therapy for insomnia (CBT-I): a randomised controlled trial (iSleep well)

Publikováno v: Trials, Vol 25, Iss 1, Pp 1-17 (2024)

Abstract Background Insomnia is a highly prevalent disorder associated with numerous adverse health outcomes. Cognitive behavioural therapy for insomnia (CBT-I) is recommended as first-line treatment by clinical guidelines but is accessible to only a

Externí odkaz: https://doaj.org/article/13736233927b4f3d98ad1be2091300e9

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Akademický článek

Effect of a prescription digital therapeutic for chronic insomnia on post-treatment insomnia severity, depression, and anxiety symptoms: results from the real-world DREAM study

Autor: Frances P. Thorndike, Charles M. Morin, Joseph Ojile, Samantha Edington, Robert Gerwien, Jason C. Ong, Emerson M. Wickwire, Lee M. Ritterband, Heidi Riney

Publikováno v: Frontiers in Psychiatry, Vol 15 (2024)

IntroductionChronic insomnia is a substantial public health burden that often presents with co-occurring depression and anxiety. Randomized clinical trials and preliminary real-world evidence have shown that digitally delivered cognitive-behavioral t

Externí odkaz: https://doaj.org/article/4d9edc333d874396aecaf219d2d329c4

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Akademický článek

Estimation bias and agreement limits between two common self-report methods of habitual sleep duration in epidemiological surveys

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

Abstract Accurate measurement of habitual sleep duration (HSD) is crucial for understanding the relationship between sleep and health. This study aimed to assess the bias and agreement limits between two commonly used short HSD self-report methods, c

Externí odkaz: https://doaj.org/article/f3d134234bbd472daf0cecd6713d52a6

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Akademický článek

Laminar Fluid Ejection for Olfactory Drug Delivery: A Proof of Concept Study

Autor: Thomas M. Morin, Nick Allan, Joshua Coutts, Jacob M. Hooker, Morgan Langille, Arron Metcalfe, Andrew Thamboo, James Jackson, Manu Sharma, Tim Rees, Kenza Enright, Ken Irving

Publikováno v: IEEE Journal of Translational Engineering in Health and Medicine, Vol 12, Pp 727-738 (2024)

Focal intranasal drug delivery to the olfactory cleft is a promising avenue for pharmaceuticals targeting the brain. However, traditional nasal sprays often fail to deliver enough medication to this specific area. We present a laminar fluid ejection

Externí odkaz: https://doaj.org/article/74d2cd79ab4e49659acd7af83e9661fb

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