Zobrazeno 1 - 10
of 461
pro vyhledávání: '"A. M. Layton"'
Autor:
Alison M. Layton, Girish Gupta, Daron Seukeran, Thivi Maruthappu, Stephanie Gaillard, Heather Whitehouse, Faisal R. Ali, Angelika Razzaque, Firas Al-Niaimi, Sarah Copperwheat
Publikováno v:
Dermatology and Therapy, Vol 14, Iss 10, Pp 2727-2738 (2024)
Abstract Introduction Acne remains one of the most common inflammatory dermatoses seen worldwide. There are significant challenges when managing acne relating to a variety of factors, including (1) lack of consensus on the use of the numerous availab
Externí odkaz:
https://doaj.org/article/0f015bbd70f3448f9f2c2bea2003cd6a
Autor:
Miriam Santer, Megan Lawrence, Sarah Pyne, Susanne Renz, Beth L Stuart, Tracey Sach, Matthew Ridd, Kim S Thomas, Jacqueline Nuttall, Natalia Permyakova, Zina Eminton, Nick Francis, Paul Little, Ingrid Muller, Irene Soulsby, Karen Thomas, Gareth Griffiths, Alison M Layton
Publikováno v:
Health Technology Assessment, Vol 28, Iss 56 (2024)
Background Acne is common, can cause significant impact on quality of life and is a frequent reason for long-term antibiotic use. Spironolactone has been prescribed for acne in women for many years, but robust evidence is lacking. Objective To evalua
Externí odkaz:
https://doaj.org/article/d1aa9dfe8a574e4080bf0fbe58d4f066
Autor:
Brima M. Younis, Rebecca Wiggins, Eltahir A.G. Khalil, Mohamed Osman, Francesco Santoro, Chiara Sonnati, Ada Keding, Maria Novedrati, Giorgio Montesi, Ali Noureldein, Elmukashfi T.A. Elmukashfi, Ala Eldin Mustafa, Mohammed Alamin, Mohammed Saeed, Khalid Salman, Ahmed J. Suliman, Amin E.A. Musa, Alison M. Layton, Charles J.N. Lacey, Paul M. Kaye, Ahmed M. Musa
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 3, Pp 101310- (2024)
In a recent phase 2a clinical trial, the candidate leishmaniasis vaccine ChAd63-KH was shown to be safe and immunogenic in Sudanese patients with post kala-azar dermal leishmaniasis (PKDL). However, its value as a stand-alone therapeutic was unknown.
Externí odkaz:
https://doaj.org/article/a583923d15cf4d3cb40a6f85f30978df
Autor:
Cherish Boxall, Susanne Renz, Zina Eminton, Jacqueline Nuttall, Alan Saji, Charlotte Cluff, Christopher Wilcox, Ingrid Muller, Alison M. Layton, Irene Soulsby, Miriam Santer
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Background The use of decentralised clinical trials (which bring trials to patients through remote processes and technology versus central on-site visits) has been thought to be a potential solution to common recruitment and retention barrie
Externí odkaz:
https://doaj.org/article/e5654ea39e4349f08009e6f469d0c5c4
Autor:
Aoife U. Daly, Rui Baptista Gonçalves, Eva Lau, Joanne Bowers, Naayema Hussaini, Maria Charalambides, Jack Coumbe, Carsten Flohr, Alison M. Layton
Publikováno v:
JEADV Clinical Practice, Vol 2, Iss 3, Pp 432-449 (2023)
Abstract How does low‐dose oral isotretinoin compare with recommended and high‐dose oral isotretinoin in terms of efficacy, adverse effect profile, duration of remission, economic profile and rate and severity of relapse? A systematic literature
Externí odkaz:
https://doaj.org/article/5435751a00a84076ad16f3aacc08d0aa
Autor:
Alison M. Layton, MB ChB, Andrew Alexis, MD, MPH, Hilary Baldwin, MD, Vincenzo Bettoli, MD, James Del Rosso, DO, Thomas Dirschka, MD, Brigitte Dréno, MD, PhD, Linda Stein Gold, MD, Julie Harper, MD, Joo Yeon Ko, MD, PhD, Khaled Al Nuaimi, MD, Hazel H. Oon, MD, Murlidhar Rajagopalan, MD, MBBS, Marco Rocha, MD, PhD, Jo-Ann See, MBBS, Jonathan Weiss, MD, Jerry Tan, MD
Publikováno v:
JAAD International, Vol 12, Iss , Pp 60-69 (2023)
Background: Acne, a commonly treated skin disease, requires patient-centered management due to its varying presentations, chronicity, and impact on health-related quality of life. Despite this, evidence-based clinical guidelines focus primarily on cl
Externí odkaz:
https://doaj.org/article/11bd54c939e14b30b7b834f62a207422
Publikováno v:
Dermatology Reports (2024)
Acne (syn. acne vulgaris) is a common inflammatory skin disorder associated with puberty and adolescence. Driven by complex interactions between the pilosebaceous unit and Cutibacterium acnes (C. acnes) bacteria, the disease is characterised by comed
Externí odkaz:
https://doaj.org/article/8722cdb52e574dccb033dab0ab41794f
Autor:
Ingrid Muller, Miriam Santer, Beth Stuart, Paul Little, Matthew J Ridd, Karen Thomas, Nick Francis, Kim S Thomas, Gareth Griffiths, Natalia V Permyakova, Jacqui Nuttall, Irene Soulsby, Alison M Layton, Tracey H Sach, Sarah Pyne, Susanne Renz, Zina Eminton, Megan Lawrence
Publikováno v:
BMJ Open, Vol 13, Iss 12 (2023)
Objective This study aims to estimate the cost-effectiveness of oral spironolactone plus routine topical treatment compared with routine topical treatment alone for persistent acne in adult women from a British NHS perspective over 24 weeks.Design Ec
Externí odkaz:
https://doaj.org/article/a2ad53dd8bc84d2ca75800e7cde0cda9
Autor:
Louise Corcoran, Ingrid Muller, Alison M. Layton, Gwennan Rucinski, Viktoria Venkatess, Anicka Sufraz, Sophie Dove, Mark Lown, Beth Stuart, Nick Francis, Miriam Santer
Publikováno v:
Skin Health and Disease, Vol 3, Iss 4, Pp n/a-n/a (2023)
Abstract Background Acne is very common, can cause considerable negative impact on quality of life and there is increasing concern over the use of long courses of oral antibiotics for this condition. Objectives (1) To critically appraise reporting in
Externí odkaz:
https://doaj.org/article/690227acb1d64c7688b2c91bd205a825
Autor:
David A. White, Aimee M. Layton, Tracy Curran, Naomi Gauthier, William B. Orr, Kendra Ward, Meg Vernon, Matthew N. Martinez, Malloree C. Rice, Katherine Hansen, Megan Prusi, Jesse E. Hansen
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Many children and adolescents with congenital and acquired heart disease (CHD) are physically inactive and participate in an insufficient amount of moderate-to-vigorous intensity exercise. Although physical activity (PA) and exercise interventions ar
Externí odkaz:
https://doaj.org/article/70ddb7e9ce674f87acc17a00ecd69124