Zobrazeno 1 - 5
of 5
pro vyhledávání: '"A. M. Klimek-Abercrombie"'
Autor:
Yi-Chun Chen, Agnieszka M. Klimek-Abercrombie, Kathryn J. Potter, Lindsay P. Pallo, Galina Soukhatcheva, Lei Dai, Melena D. Bellin, C. Bruce Verchere
Publikováno v:
American Journal of Transplantation. 22:1992-2005
Pancreatic islet transplantation has therapeutic potential in type 1 diabetes and is also an established therapy in chronic pancreatitis. However, the long-term transplant outcomes are modest. Identifying indicators of graft function will aid the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0700c59034f03eb32490bbce4964494
https://doi.org/10.1111/ajt.17076
https://doi.org/10.1111/ajt.17076
Autor:
Kathryn J. Potter, Galina Soukhatcheva, Yi-Chun Chen, L. P. Pallo, A. M. Klimek-Abercrombie, M. Bellin, C. B. Verchere, D. Lei
Autologous pancreatic islet transplantation is an established therapy for patients with chronic pancreatitis. However, the long-term transplant outcomes are modest. Identifying indicators of graft function will aid the preservation of transplanted is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cd20eb3046beec3cc061fb144cbb45a
https://doi.org/10.1101/2021.10.17.464749
https://doi.org/10.1101/2021.10.17.464749
Autor:
Yi-Chun Chen, Jaques A. Courtade, Paul C. Orban, Nirja Patel, Carla J. Greenbaum, Behzad Najafian, Agnieszka M. Klimek-Abercrombie, Graydon S. Meneilly, Phoebe Y. T. Lu, C. Bruce Verchere, Cate Speake, Constadina Panagiotopoulos, Garth L. Warnock
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 102:2595-2603
Context: Islet amyloid is a feature of β-cell failure in type 2 diabetes (T2D) and type 1 diabetes (T1D) recipients of islet transplants. Islet amyloid contains islet amyloid polypeptide (IAPP; amylin), a circulating peptide that is produced in β c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201f9716edcf53dc32eea56037bfc4cb
https://doi.org/10.1210/jc.2016-2773
https://doi.org/10.1210/jc.2016-2773
Autor:
Garth L. Warnock, C. Bruce Verchere, Kathryn J. Potter, Clara Westwell-Roper, Agnieszka M. Klimek-Abercrombie
Publikováno v:
Diabetes. 63:12-19
β-Cell replacement by islet transplantation is a potential curative therapy for type 1 diabetes. Despite advancements in islet procurement and immune suppression that have increased islet transplant survival, graft function progressively declines, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec052773a94621611ff003e4f8777f8b
https://doi.org/10.2337/db12-0364
https://doi.org/10.2337/db12-0364
Autor:
Clara Westwell-Roper, Joel Montane, C. Bruce Verchere, Kathryn J. Potter, Agnieszka M. Klimek-Abercrombie
Publikováno v:
Diabetes, Obesity and Metabolism. 14:68-77
Amyloid forms within pancreatic islets in type 2 diabetes from aggregates of the β-cell peptide islet amyloid polypeptide (IAPP). These aggregates are toxic to β-cells, inducing β-cell death and dysfunction, as well as inciting islet inflammation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a968097e60849b3292b417011fdbd11a
https://doi.org/10.1111/j.1463-1326.2012.01657.x
https://doi.org/10.1111/j.1463-1326.2012.01657.x