Zobrazeno 1 - 5
of 5
pro vyhledávání: '"A. M. Kieva"'
Autor:
E. K. Mgdsyan, D. V. Yukhacheva, E. A. Malakhova, D. E. Pershin, A. M. Kieva, E. V. Raikina, N. M. Kondratieva, E. I. Alekseeva, Yu. A. Rodina, A. Y. Shcherbina
Publikováno v:
Pediatric Hematology/Oncology and Immunopathology. 22:139-146
X-linked agammaglobulinemia (XLA), or Bruton’s agammaglobulinemia, – is a primary immunodeficiency, caused by defects in the BTK gene encoding Bruton’s tyrosine kinase. The BTK defects lead to the arrest of B-lymphocyte development and, as a re
Autor:
O.A. Shvets, A.Yu. Shcherbina, E.A. Deordieva, N. S. Smetanina, A.V. Pshonkin, Dmitry Pershin, A. M. Kieva, Maria Kurnikova
Publikováno v:
Pediatric Hematology/Oncology and Immunopathology. 20:170-179
Autoimmune lymphoproliferative syndrome is a primary immunodeficiency caused by defective FAS-mediated apoptosis and usually accompanied by hypergammaglobulinemia. Yet some exceptions take place in the cohort of patients that complicated timely diagn
Autor:
Alexandra Laberko, E.V. Raykina, G.N. Tereshenko, V.I. Burlakov, A.A. Roppelt, E.V. Deripapa, D.V. Bogdanova, Yu.A. Rodina, I.N. Abramova, Immunology named after Dmitry Rogachev, Moscow, Russia, A.Yu. Shcherbina, D.V. Yukhacheva, Anna Mukhina, D.S. Abramov, A.L. Khoreva, O.A. Shvets, Dmitry Pershin, M.Yu. Alexenko, A. M. Kieva, V.A. Vedmedskia, A.V. Pshonkin, G.G. Solopova
Publikováno v:
Pediatria. Journal named after G.N. Speransky. 100:22-30
CTLA4 deficiency is a primary immunodeficiency state (PIDS) caused by monoallelic mutations in the gene of the same name, and belongs to the group of immunodeficiencies with immune dysregulation. This work analyzes the results of 11 patients with CTL
Autor:
I.V. Mersiyanova, V. A. Vedmedskaya, M.A. Maschan, E.A. Kulakovskaya, M.S. Fadeeva, A.L. Khoreva, A.Yu. Shcherbina, E.A. Malakhova, I.S. Vladimirov, Dmitry Pershin, E.V. Raikina, Yu.A. Rodina, A. M. Kieva, O.B. Lodoeva, Immunology named after Dmitry Rogachev, Moscow, Russia
Publikováno v:
Pediatria. Journal named after G.N. Speransky. 100:31-40
Compensatory or revertant somatic mutations (RSM) is a well-known phenomenon in patients with PIs. RSM can lead to the restoration of functional protein expression in some cell populations and thus influence the severity of clinical manifestations in
Autor:
E. A. Victorova, Dmitry Pershin, N. B. Kuzmenko, V. I. Burlakov, A. M. Kieva, V. A. Vedmedskaya, I.V. Mersiyanova, Z. A. Nesterenko, E. V. Raykina, T. V. Varlamova, E. V. Deripapa
Publikováno v:
Pediatric Hematology/Oncology and Immunopathology. 18:104-111
Primary immunodeficiencies (PIDS) are genetically caused heterogeneous diseases of the immune system. One of the genetic phenomenon affecting the phenotypic diversity of PIDS is a reverse somatic mosaicism (RM) observed in different groups of PIDS. T