Zobrazeno 1 - 10
of 685
pro vyhledávání: '"A. M. Kenney"'
Autor:
Leon F. McSwain, Claire E. Pillsbury, Ramona Haji-Seyed-Javadi, Sandip Kumar Rath, Victor Chen, Tiffany Huang, Shubin W. Shahab, Haritha Kunhiraman, James Ross, Gabrielle A. Price, Abhinav Dey, Dolores Hambardzumyan, Tobey MacDonald, David S. Yu, Christopher C. Porter, Anna M. Kenney
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Y-box binding protein 1 (YBX1 or YB1) is a therapeutically relevant oncoprotein capable of RNA and DNA binding and mediating protein–protein interactions that drive proliferation, stemness, and resistance to platinum-based therapies. Given
Externí odkaz:
https://doaj.org/article/425775788bf245a2acd870d8014152f4
Autor:
Leon F. McSwain, Claire E. Pillsbury, Ramona Haji‑Seyed‑Javadi, Sandip Kumar Rath, Victor Chen, Tiffany Huang, Shubin W. Shahab, Haritha Kunhiraman, James Ross, Gabrielle A. Price, Abhinav Dey, Dolores Hambardzumyan, Tobey MacDonald, David S. Yu, Christopher C. Porter, Anna M. Kenney
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/ff47403e1e7249699d95fc35ba65c551
Autor:
Ian M. Kenney, Oliver Beckstein
Publikováno v:
Biophysical Reports, Vol 3, Iss 3, Pp 100120- (2023)
Kinetic and thermodynamic models of biological systems are commonly used to connect microscopic features to system function in a bottom-up multiscale approach. The parameters of such models—free energy differences for equilibrium properties and in
Externí odkaz:
https://doaj.org/article/f213fad499ca457c9ca0e3427c32f864
Autor:
Iven Winkelmann, Povilas Uzdavinys, Ian M. Kenney, Joseph Brock, Pascal F. Meier, Lina-Marie Wagner, Florian Gabriel, Sukkyeong Jung, Rei Matsuoka, Christoph von Ballmoos, Oliver Beckstein, David Drew
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
By determining the crystal structure of the Na + /H + antiporter NhaA at active pH, the authors show how substrate accessibility to the ion-binding site can be controlled by pH sensitive switch located on the cytoplasmic surface.
Externí odkaz:
https://doaj.org/article/d75c94092f084db7b84a655abf5cc842
Autor:
John K. Botson, John R. P. Tesser, Ralph Bennett, Howard M. Kenney, Paul M. Peloso, Katie Obermeyer, Yang Song, Brian LaMoreaux, Lin Zhao, Yan Xin, Jason Chamberlain, Srini Ramanathan, Michael E. Weinblatt, Jeff Peterson
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-12 (2022)
Abstract Background Publications suggest immunomodulation co-therapy improves responder rates in uncontrolled/refractory gout patients undergoing pegloticase treatment. The MIRROR open-label trial showed a 6-month pegloticase + methotrexate co-therap
Externí odkaz:
https://doaj.org/article/4fc2a178d072458a9a48f53d9921ee85
Autor:
Abubakar Siddique, Nimat Ullah, Amjad Ali, Ami Patel, Terence Moore, Sophia M. Kenney, Erika Ganda, Abdur Rahman
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 29, Iss , Pp 131-135 (2022)
ABSTRACT: Objectives: Antimicrobial-resistant livestock-associated Salmonella enterica serovar Agona infection poses a significant public health threat worldwide. The present study aimed to identify antibiotic resistance genes in livestock-associated
Externí odkaz:
https://doaj.org/article/4020ceea7f4f4b5f8501d37a7104f685
Publikováno v:
Cognitive Research, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract We used a driving simulator to investigate landmark-based route navigation in young adults. Previous research has examined how proximal and distal landmarks influence route navigation, however, these effects have not been extensively tested
Externí odkaz:
https://doaj.org/article/a4be88208c0c49fdae8ffa6542147425
Publikováno v:
Antimicrobial Stewardship & Healthcare Epidemiology, Vol 3 (2023)
Abstract Objective: To evaluate antibiotic prescribing in ambulatory oncology clinics and to identify opportunities to improve antibiotic use. Methods: Retrospective cohort of adult patients who received care at 4 ambulatory oncology clinics from
Externí odkaz:
https://doaj.org/article/870a79660a364a6fbadc0512477ca733
Autor:
Irene Orlow, Keimya D Sadeghi, Sharon N Edmiston, Jessica M Kenney, Cecilia Lezcano, James S Wilmott, Anne E Cust, Richard A Scolyer, Graham J Mann, Tim K Lee, Hazel Burke, Valerie Jakrot, Ping Shang, Peter M Ferguson, Tawny W Boyce, Jennifer S Ko, Peter Ngo, Pauline Funchain, Judy R Rees, Kelli O'Connell, Honglin Hao, Eloise Parrish, Kathleen Conway, Paul B Googe, David W Ollila, Stergios J Moschos, Eva Hernando, Douglas Hanniford, Diana Argibay, Christopher I Amos, Jeffrey E Lee, Iman Osman, Li Luo, Pei-Fen Kuan, Arshi Aurora, Bonnie E Gould Rothberg, Marcus W Bosenberg, Meg R Gerstenblith, Cheryl Thompson, Paul N Bogner, Ivan P Gorlov, Sheri L Holmen, Elise K Brunsgaard, Yvonne M Saenger, Ronglai Shen, Venkatraman Seshan, Eduardo Nagore, Marc S Ernstoff, Klaus J Busam, Colin B Begg, Nancy E Thomas, Marianne Berwick, InterMEL Consortium
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0269324 (2023)
IntroductionWe are conducting a multicenter study to identify classifiers predictive of disease-specific survival in patients with primary melanomas. Here we delineate the unique aspects, challenges, and best practices for optimizing a study of gener
Externí odkaz:
https://doaj.org/article/2122630446b94345873b74cdda1850a8
Publikováno v:
Antimicrobial Stewardship & Healthcare Epidemiology, Vol 3 (2023)
We compared optimal antibiotic prescribing before and after implementing an interpretive β-lactamase microbiology comment for Haemophilus influenzae and Moraxella catarrhalis in lower respiratory-tract infections. The postintervention group was asso
Externí odkaz:
https://doaj.org/article/d81643ac3d8244ea80fc3765107306df