Zobrazeno 1 - 10
of 2 209
pro vyhledávání: '"A. M. Kaye"'
Autor:
Bing H. Wang, Remy Robert, Francine Z. Marques, Niwanthi Rajapakse, Helen Kiriazis, Charles R. Mackay, David M. Kaye
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Cardiorenal fibrosis is a common feature of chronic cardiovascular disease and recent data suggests that cytokines and chemokines may also drive fibrosis. Here we tested the hypothesis that CXCR7, a highly conserved chemokine receptor, contr
Externí odkaz:
https://doaj.org/article/39ae76b2ee2b4c3481cce768b048591b
Autor:
Emilia Nan Tie, Emil Wolsk, Shane Nanayakkara, Donna Vizi, Justin Mariani, Jacob Eifer Moller, Christian Hassager, Finn Gustafsson, David M. Kaye
Publikováno v:
ESC Heart Failure, Vol 11, Iss 5, Pp 2557-2565 (2024)
Abstract Aims Heart failure with preserved ejection fraction (HFpEF) is associated with an array of central and peripheral haemodynamic and metabolic changes. The exact pathogenesis of exercise limitation in HFpEF remains uncertain. Our aim was to co
Externí odkaz:
https://doaj.org/article/49cdd9ff603442a0ba4f287eba7a06d9
Autor:
Jason E. Bloom, MBBS, Vishal Goel, MBBS, David Anderson, MBChB, Susie Cartledge, BN, PhD, Ziad Nehme, PhD, Jocasta Ball, PhD, Amminadab Eliakundu, PhD, William Chan, MBBS, PhD, Derek P. Chew, MBBS, PhD, David M. Kaye, MBBS, PhD, Dion Stub, MBBS, PhD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 12, p e1177 (2024)
OBJECTIVES:. We sought to describe the indications for vasoactive medication administration, hemodynamic treatment targets, and specific agents used by various international emergency medical service (EMS) providers. DESIGN AND SETTING:. In March 202
Externí odkaz:
https://doaj.org/article/f7cc0bf80bb2482583eb0ea248649691
Autor:
Jennifer Zhou, Shane Nanayakkara, Rozanne Johnston, Ellen Gardner, Nay Min Htun, Sonny Palmer, Samer Noaman, Liam Guiney, David M. Kaye, Antony S. Walton, Dion Stub
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 55, Iss , Pp 101561- (2024)
Background: Socioeconomic status (SES) is an important determinant of healthcare outcomes in many settings, but few studies have evaluated the impact of SES among patients with aortic stenosis (AS). We sought to explore the association between SES an
Externí odkaz:
https://doaj.org/article/7ad87f019ca5405e8f38c86de2cce054
Autor:
Madhurima Roy, Ritika Sengupta, Bidhan Chandra Chakraborty, Uttara Chatterjee, Esther von Stebut, Paul M Kaye, Mitali Chatterjee
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 11, p e0012655 (2024)
BackgroundPost Kala-azar Dermal Leishmaniasis (PKDL) is a dermal sequel of visceral leishmaniasis (VL), poses a significant threat to the success of ongoing kala-azar elimination program, due to its potential role in sustaining transmission cycles an
Externí odkaz:
https://doaj.org/article/cbceca4f978040bebf9e2ea7c6a9ce22
Autor:
Max C Waugh, Karen I Cyndari, Tom J Lynch, Soomin Koh, Ferney Henao-Ceballos, Jacob J Oleson, Paul M Kaye, Christine A Petersen
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 11, p e0012363 (2024)
Dogs represent the primary reservoir for Leishmania infantum human visceral leishmaniasis (VL) transmitted through phlebotomine sand flies. Public health initiatives targeting zoonotic VL commonly focus on dogs with severe clinical disease, often in
Externí odkaz:
https://doaj.org/article/c5a3c2e2613d4fd5afbd0789e148f6c3
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
An aging population and an increasing incidence of cardiovascular risk factors form the basis for a global rising prevalence of valvular heart disease (VHD). Research to further our understanding of the pathophysiology of VHD is often confined to the
Externí odkaz:
https://doaj.org/article/f498efa4c3344d1396cd45b2083b72b7
Autor:
Kamryn E. Jones, Shaun L. Hayden, Hannah R. Meyer, Jillian L. Sandoz, William H. Arata, Kylie Dufrene, Corrado Ballaera, Yair Lopez Torres, Patricia Griffin, Adam M. Kaye, Sahar Shekoohi, Alan D. Kaye
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 7, Pp 6315-6327 (2024)
Worldwide, hypertension is the leading risk factor for cardiovascular disease and death. An estimated 122 million people, per the American Heart Association in 2023, have been diagnosed with this common condition. It is generally agreed that the prim
Externí odkaz:
https://doaj.org/article/81aaae4d3bc7464bb1891d0de8ef5783
Autor:
Alan D. Kaye, Joseph P. Tassin, William C. Upshaw, Camille M. Robichaux, Mark V. Frolov, Mark M. Dupaquier, Julia E. Fox, Jeffrey Sterritt, Jibin Mathew, Sahar Shekoohi, Adam M. Kaye, Amber N. Edinoff
Publikováno v:
Neurology and Therapy, Vol 13, Iss 4, Pp 965-973 (2024)
Abstract Etizolam is a thienodiazepine derivative which produces an anxiolytic effect similar to benzodiazepines such as alprazolam (Xanax). Like classic benzodiazepines, etizolam has a high affinity towards the GABAA receptor, and allosterically pot
Externí odkaz:
https://doaj.org/article/b991e6c6ce834132bf26f28725a9bf89
Autor:
Alan D. Kaye, Dominique M. Perilloux, Alison M. Hawkins, Grace C. Wester, Amanda R. Ragaland, Sage V. Hebert, Julian Kim, Michael Heisler, Rucha A. Kelkar, Azem A. Chami, Sahar Shekoohi, Adam M. Kaye
Publikováno v:
Pain and Therapy, Vol 13, Iss 3, Pp 481-493 (2024)
Abstract Chronic pain, a complex and debilitating condition, involves intricate interactions between central and peripheral inflammatory processes. Cytokines, specifically tumor necrosis factor (TNF) and interleukins (IL), are key mediators in the in
Externí odkaz:
https://doaj.org/article/ee959da8fad3404e818d74c8897e39d3