Zobrazeno 1 - 10
of 38
pro vyhledávání: '"A. M. Kanhed"'
Publikováno v:
Molecular Diversity.
Diabetes is a leading cause of kidney failure, blindness, heart attacks and lower limb amputation. Prevalence of diabetes is rising globally. α-glucosidase is validated target for controlling hyperglycemia because of its role in catalysing hydrolysi
Autor:
Ashish M. Kanhed, Amisha Vora, Ami Thakkar, Gudepalya Renukaiah Rudramurthy, Radha Krishan Shandil, Maddipatla Yogi, Rajappa Harisha, Mayas Singh, Shridhar Narayanan
COVID-19 caused by novel corona virus (SARS-CoV-2) is the major pandemic of the decade claiming millions of lives causing severe disruptions to society. Despite rapid development of COVID-19 vaccines, condition is still not under control and newer an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5a65f8ae6c8b7e1a61a14106c40f581
https://doi.org/10.21203/rs.3.rs-2529092/v1
https://doi.org/10.21203/rs.3.rs-2529092/v1
Publikováno v:
RSC Advances. 12:15196-15214
Pseudomonas aeruginosa infections are attributed to its ability to form biofilms and are difficult to eliminate with antibiotic treatment.
Autor:
Divya M. Teli, Mahesh T. Chhabria, Dushyant V. Patel, Nirav R. Patel, Ashish M. Kanhed, Amisha Vora, Bhavik S. Shah, Mange Ram Yadav
Publikováno v:
International Journal of Quantitative Structure-Property Relationships. 6:58-77
A novel coronavirus is the causative agent identified for the current COVID-19 outbreak. Globally, more than 43 million people have been infected by this virus. The total number of deaths has surpassed 1.6 million across 210 countries due to the curr
Autor:
Kamlesh H. Chavan, Anshuman Sinha, Nathrao Ankushrao Kedar, Vishal Kumar Agrahari, Ashish M. Kanhed
Publikováno v:
Journal of the Iranian Chemical Society. 18:1801-1813
Toward the development of selective cyclooxygenase-2 inhibitors, a series of pyrrolidine derivatives is described. All the compounds containing sulfonamide, ester, nitrile, acid, amide and urea functionalities were computationally screened, and bindi
Autor:
Priyanka S Thakor, Kirti V. Patel, Mange Ram Yadav, Anshuman Sinha, Navnit K Prajapati, Nirav R. Patel, Kishan B Patel, Dushyant V. Patel, Ashish M. Kanhed
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:2498-2515
To confront a disease like Alzheimer's disease having complex pathogenesis, development of multitarget-directed ligands has emerged as a promising drug discovery approach. In our endeavor towards the development of multitarget-directed ligands for Al
Autor:
Kishan B Patel, Pallav M. Gandhi, Nirav R. Patel, Dharti B. Shah, Kirti V. Patel, Ashish M. Kanhed, Divya M. Teli, Bharat N Chaudhary, Sagar P. Patel, Navnit K Prajapati, Mange Ram Yadav, Dushyant V. Patel
Publikováno v:
ACS Chemical Neuroscience. 11:3557-3574
The inadequate clinical efficacy of the present anti-Alzheimer's disease (AD) drugs and their low impact on the progression of Alzheimer's disease in patients have revised the research focus from single targets to multitarget-directed ligands. A nove
Autor:
Mange Ram Yadav, Mahesh T. Chhabria, Ashish M. Kanhed, Divya M. Teli, Dushyant V. Patel, Nirav R. Patel
Publikováno v:
Molecular Diversity
The Corona virus Disease (COVID-19) is caused because of novel coronavirus (SARS-CoV-2) pathogen detected in China for the first time, and from there it spread across the globe creating a worldwide pandemic of severe respiratory complications. The vi
Publikováno v:
RSC advances. 12(24)
Publikováno v:
Molecular Diversity
In the present work, a hit molecule obtained from zinc ‘clean drug-like database’ by systematically performed computational studies was modified chemically to obtain different derivatives (VS1–VS25). Structures of synthesized derivatives were c