Zobrazeno 1 - 10
of 28
pro vyhledávání: '"A. M. Inkster"'
Autor:
A. Khan, A. M. Inkster, M. S. Peñaherrera, S. King, S. Kildea, T. F. Oberlander, D. M. Olson, C. Vaillancourt, U. Brain, E. O. Beraldo, A. G. Beristain, V. L. Clifton, G. F. Del Gobbo, W. L. Lam, G. A. S. Metz, J. W. Y. Ng, E. M. Price, J. M. Schuetz, V. Yuan, É. Portales-Casamar, W. P. Robinson
Publikováno v:
Epigenetics & Chromatin, Vol 16, Iss 1, Pp 1-22 (2023)
Abstract Background Genome-wide DNA methylation (DNAme) profiling of the placenta with Illumina Infinium Methylation bead arrays is often used to explore the connections between in utero exposures, placental pathology, and fetal development. However,
Externí odkaz:
https://doaj.org/article/8b96f07395584eb49a0b50d3239d7f7e
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Background: A growing body of literature has reported molecular and histological changes in the human placenta in association with preeclampsia (PE). Placental DNA methylation (DNAme) and transcriptomic patterns have revealed molecular subgroups of P
Externí odkaz:
https://doaj.org/article/a257ee21585c48918ec7c6d7def159fa
Autor:
William Casazza, Amy M. Inkster, Giulia F. Del Gobbo, Victor Yuan, Fabien Delahaye, Carmen Marsit, Yongjin P. Park, Wendy P. Robinson, Sara Mostafavi, Jessica K. Dennis
Publikováno v:
iScience, Vol 27, Iss 2, Pp 109047- (2024)
Summary: Molecular quantitative trait loci (QTLs) allow us to understand the biology captured in genome-wide association studies (GWASs). The placenta regulates fetal development and shows sex differences in DNA methylation. We therefore hypothesized
Externí odkaz:
https://doaj.org/article/220ea8500dd1436fa1eeef520eddff9d
Autor:
Chaini Konwar, Rebecca Asiimwe, Amy M. Inkster, Sarah M. Merrill, Gian L. Negri, Maria J. Aristizabal, Christopher F. Rider, Julie L. MacIsaac, Christopher Carlsten, Michael S. Kobor
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-18 (2021)
Abstract Background Understanding the molecular basis of susceptibility factors to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a global health imperative. It is well-established that males are more likely to acquire
Externí odkaz:
https://doaj.org/article/eb8dddcdb6ed41d08f9b4f0c914873af
Autor:
Yuyin Yi, Hua Zhu, Christian Klausen, Hsun-Ming Chang, Amy M. Inkster, Jefferson Terry, Peter C. K. Leung
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Many pregnancy disorders, including early-onset preeclampsia (EOPE), are associated with defects in placental trophoblast cell invasion and differentiation during early placental development. Bone morphogenetic protein 2 (BMP2) belongs to the TGF-β
Externí odkaz:
https://doaj.org/article/0617d09752c248fb95f50d1119cf54e0
Background A growing body of literature has reported molecular and histological changes in the human placenta in association with preeclampsia (PE). Placental DNA methylation (DNAme) and transcriptomic patterns have revealed molecular subgroups of PE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d37a365ef67a7d0dd4d0119d1dae30f
https://doi.org/10.21203/rs.3.rs-2949161/v1
https://doi.org/10.21203/rs.3.rs-2949161/v1
Publikováno v:
Epigenetics & Chromatin. 16
BackgroundMany human disease phenotypes manifest differently by sex, making the development of methods for incorporating X and Y-chromosome data into analyses vital. Unfortunately, X and Y chromosome data are frequently excluded from large-scale anal
Autor:
Christopher Carlsten, Maria J. Aristizabal, Michael S. Kobor, Christopher F. Rider, Sarah M. Merrill, Amy M. Inkster, Chaini Konwar, J.L. MacIsaac, Gian Luca Negri, Rebecca Asiimwe
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-18 (2021)
Epigenetics & Chromatin
Epigenetics & Chromatin
Background Understanding the molecular basis of susceptibility factors to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a global health imperative. It is well-established that males are more likely to acquire SARS-CoV-
Autor:
William Casazza, Amy M. Inkster, Giulia F. Del Gobbo, Victor Yuan, Fabien Delahaye, Carmen Marsit, Yongjin P. Park, Wendy P. Robinson, Sara Mostafavi, Jessica K Dennis
SummaryMolecular quantitative trait loci (QTL) allow us to understand the biology captured in genome-wide association studies (GWAS). The placenta regulates fetal development, and shows sex differences in DNA methylation. We therefore hypothesized th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::790b02a466b211fff31af3e9b2a978c5
https://doi.org/10.1101/2022.10.04.22280695
https://doi.org/10.1101/2022.10.04.22280695
Publikováno v:
Epigeneticschromatin. 16(1)
Many human disease phenotypes manifest differently by sex, making the development of methods for incorporating X and Y-chromosome data into analyses vital. Unfortunately, X and Y chromosome data are frequently excluded from large-scale analyses of th