Zobrazeno 1 - 10
of 92
pro vyhledávání: '"A. M. Davalli"'
Autor:
F. Bertuzzi M.D., P. Garancini, C. Socci, R. Nano, M. V. Taglietti, M. Santopinto, V. Di Carlo, A. M. Davalli
Publikováno v:
Cell Transplantation, Vol 8 (1999)
We report the average insulin response to acute glucose measured by in vitro perifusion of pancreatic islets isolated from 80 consecutive human organs. Different perifusion parameters were considered [basal release, stimulation index (SI), time to pe
Externí odkaz:
https://doaj.org/article/6fe9f1baf24d44f6a0f72036b9f5f470
Autor:
Carla Perego, Eliana S. Di Cairano, Alessandra Galli, Stefania Moretti, Elena Bazzigaluppi, Victoria Frolich Centonze, Amalia Gastaldelli, Emma Assi, Paolo Fiorina, Massimo Federici, Ottavia Porzio, Federico Bertuzzi, Alberto M. Davalli, Franco Folli
Publikováno v:
Pharmacological Research, Vol 177, Iss , Pp 106130- (2022)
Islet cell surface autoantibodies were previously found in subjects with type 1 diabetes mellitus (T1DM), but their target antigens and pathogenic mechanisms remain elusive. The glutamate transporter solute carrier family 1, member 2 (GLT1/EAAT2) is
Externí odkaz:
https://doaj.org/article/380a126dc7ac46df9a35236c18b92a58
Autor:
S. Martinenghi, Lorenzo Piemonti, Cristina Brigatti, Giordano Vitali, Giovanni Landoni, Vito Lampasona, Marina Scavini, Ilaria Marzinotto, Luigi di Filippo, Fabio Ciceri, Chiara Molinari, Alberto M. Davalli, Alessia Mercalli, Andrea Laurenzi, Patrizia Rovere-Querini, Massimiliano Secchi, Emanuele Bosi, Raffaella Melzi, Cristina Tresoldi, Amelia Caretto, Elena Bazzigaluppi
Publikováno v:
Diabetologia
Aims/hypothesis The aim of the study was to characterise the humoral response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients with diabetes. Demonstrating the ability to mount an appropriate antibody response in the p
Autor:
Subhash Kamath, Alberto O Chavez, Amalia Gastaldelli, Francesca Casiraghi, Glenn A Halff, Gregory A Abrahamian, Alberto M Davalli, Raul A Bastarrachea, Anthony G Comuzzie, Rodolfo Guardado-Mendoza, Lilia M Jimenez-Ceja, Vicki Mattern, Ana Maria Paez, Andrea Ricotti, Mary E Tejero, Paul B Higgins, Iram Pablo Rodriguez-Sanchez, Devjit Tripathy, Ralph A DeFronzo, Edward J Dick, Gary W Cline, Franco Folli
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27617 (2011)
Non-alcoholic fatty liver disease (NAFLD) is characterized by accumulation of triglycerides (TG) in hepatocytes, which may also trigger cirrhosis. The mechanisms of NAFLD are not fully understood, but insulin resistance has been proposed as a key det
Externí odkaz:
https://doaj.org/article/e4cf894040c34b51b73a7c0dc59cb34b
Autor:
Alberto M. Davalli M.D., Lucia Perego, Federico Bertuzzi, Giovanna Finzi, Stefano La Rosa, Adam Blau, Claudia Placidi, Rita Nano, Luisa Gregorini, Carla Perego, Carlo Capella, Franco Folli M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 17 (2008)
To learn more about nonimmune-mediated islet graft failure, we transplanted different preparations (preps) of isolated human islets under the kidney capsule of streptozotocin (STZ)-diabetic nude mice. One month after the implantation of 1,000 or 2,00
Externí odkaz:
https://doaj.org/article/0a2ec93719814613a3d4a45046aff5c5
Publikováno v:
Cell Transplantation, Vol 11 (2002)
We recently developed two rat pituitary GH3 cell clones engineered to secrete human insulin (InsGH3). InsGH3 cells convert proinsulin into mature insulin, which is partially stored into a readily releasable pool of secretory granules. The efficiency
Externí odkaz:
https://doaj.org/article/0212dcdfdb7f4e1a8cb5de51245f7458
Autor:
Alberto M. Davalli M.D., Francesca Galbiati, Federico Bertuzzi, Luca Polastri, Antonio E. Pontiroli, Lucia Perego, Massimo Freschi, Guido Pozza, Franco Folli, Cesare Meoni
Publikováno v:
Cell Transplantation, Vol 9 (2000)
In a companion article, we describe the engineering and characterization of pituitary GH3 cell clones stably transfected with a furin-cleavable human insulin cDNA (InsGH3 cells). This article describes the performance of InsGH3 (clones 1 and 7) cell
Externí odkaz:
https://doaj.org/article/39aa5678846f4c388968ed1ed50dc219
Autor:
A. Galli, Carla Perego, Giovanna Finzi, Stefano La Rosa, Alberto M. Davalli, Franco Folli, Rodolfo Guardado Mendoza, Edward J. Dick
Publikováno v:
Diabetes, obesitymetabolism. 20
While a number of structural and cellular abnormalities occur in the islet of Langerhans in diabetes, and in particular in type 2 diabetes, the focus has been mostly on the insulin producing β-cells and only more recently on glucagon producing α- a
Autor:
P. Marciani, Franco Folli, V. F. Sacchi, Eliana S. Di Cairano, Michela Castagna, Alberto M. Davalli, S. Moretti, Carla Perego
Publikováno v:
Journal of Cellular Physiology. 231:756-767
Islets of Langerhans control whole body glucose homeostasis, as they respond, releasing hormones, to changes in nutrient concentrations in the blood stream. The regulation of hormone secretion has been the focus of attention for a long time because i
Autor:
Claudia Placidi, Victoria E. Centonze, Alberto M. Davalli, Federico Bertuzzi, Franco Folli, Carla Perego, V. Franca Sacchi, Eliana S. Di Cairano, Carlo Capella, Stefano La Rosa, Giovanna Finzi, Lucia Perego, Paola Conti, Silvia Sala, Francesca Casiraghi
Publikováno v:
Journal of Biological Chemistry. 286:14007-14018
Glutamate is the major excitatory neurotransmitter of the central nervous system (CNS) and may induce cytotoxicity through persistent activation of glutamate receptors and oxidative stress. Its extracellular concentration is maintained at physiologic