Zobrazeno 1 - 10
of 119
pro vyhledávání: '"A. M. Crago"'
Autor:
A. N. Shoushtari, J. Landa, D. Kuk, A. Sanchez, B. Lala, N. Schmidt, C. Okoli, P. Chi, M. A. Dickson, M. M. Gounder, M. L. Keohan, A. M. Crago, W. D. Tap, S. P. D’Angelo
Publikováno v:
Sarcoma, Vol 2016 (2016)
Background. Leiomyosarcomas (LMS) represent a heterogeneous subset of soft tissue sarcomas. Factors influencing prognosis for patients with metastatic extrauterine LMS (euLMS) are not well described. Limited data are available regarding responses to
Externí odkaz:
https://doaj.org/article/da7846f87c7e4c9ca874bbe16ac901d4
Autor:
Cristina Valero, Mark Lee, Douglas Hoen, Kate Weiss, Daniel W. Kelly, Prasad S. Adusumilli, Paul K. Paik, George Plitas, Marc Ladanyi, Michael A. Postow, Charlotte E. Ariyan, Alexander N. Shoushtari, Vinod P. Balachandran, A. Ari Hakimi, Aimee M. Crago, Kara C. Long Roche, J. Joshua Smith, Ian Ganly, Richard J. Wong, Snehal G. Patel, Jatin P. Shah, Nancy Y. Lee, Nadeem Riaz, Jingming Wang, Ahmet Zehir, Michael F. Berger, Timothy A. Chan, Venkatraman E. Seshan, Luc G. T. Morris
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
There is an unmet clinical need for simple, accessible biomarkers to select patients who are more likely to respond to immune checkpoint therapy. Here the authors show that a lower neutrophil-to-lymphocyte ratio is associated with better overall and
Externí odkaz:
https://doaj.org/article/dd218269962540ee8add1e4fa781b7e2
Autor:
Emily Z. Keung, Kate J. Krause, Jessica Maxwell, Carol D. Morris, Aimee M. Crago, Matthew T. Houdek, John Kane, Valerae Lewis, Dario Callegaro, Benjamin Miller, Alexander J. Lazar, Rebecca Gladdy, Chandrajit P. Raut, Nicola Fabbri, Waddah Al-Refaie, Mark Fairweather, Sandra L. Wong, Christina L. Roland
Publikováno v:
Annals of Surgical Oncology. 30:958-967
Autor:
Marta Kovatcheva, Will Liao, Mary E. Klein, Nicolas Robine, Heather Geiger, Aimee M. Crago, Mark A. Dickson, William D. Tap, Samuel Singer, Andrew Koff
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Therapy induced senescence (TIS) is a growth suppressive program activated by cytostatic agents in some cancer cells. Here the authors show that the chromatin remodeling enzyme ATRX is a regulator of TIS and drives cells into this state via multiple
Externí odkaz:
https://doaj.org/article/7f628acc50d64801af6befbeedb96ee3
Autor:
Sandra P. D'Angelo, William D. Tap, Cristina R. Antonescu, Joseph P. Erinjeri, Sinchun Hwang, Sam S. Yoon, Aimee M. Crago, Edmund K. Bartlett, Samuel Singer, Travis Adamson, Evan Rosenbaum, Benjamin A. Nacev, Sujana Movva, Mary Louise Keohan, Mrinal M. Gounder, Mark A. Dickson, Ping Chi, Jason E. Chan, Viswatej Avutu, Allison L. Richards, Karissa A. Whiting, Li-Xuan Qin, Ciara M. Kelly
Normalized Tryptophan Concentrate Over Time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6109f9cc589922d72ab9e49208351223
https://doi.org/10.1158/1078-0432.22651621
https://doi.org/10.1158/1078-0432.22651621
Autor:
Sandra P. D'Angelo, William D. Tap, Cristina R. Antonescu, Joseph P. Erinjeri, Sinchun Hwang, Sam S. Yoon, Aimee M. Crago, Edmund K. Bartlett, Samuel Singer, Travis Adamson, Evan Rosenbaum, Benjamin A. Nacev, Sujana Movva, Mary Louise Keohan, Mrinal M. Gounder, Mark A. Dickson, Ping Chi, Jason E. Chan, Viswatej Avutu, Allison L. Richards, Karissa A. Whiting, Li-Xuan Qin, Ciara M. Kelly
Purpose:Epacadostat, an indole 2,3 dioxygenase 1 (IDO1) inhibitor, proposed to shift the tumor microenvironment toward an immune-stimulated state, showed early promise in melanoma but has not been studied in sarcoma. This study combined epacadostat w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5370a27191f4e07d1a50287b7da7d7fc
https://doi.org/10.1158/1078-0432.c.6604903
https://doi.org/10.1158/1078-0432.c.6604903
Autor:
Sandra P. D'Angelo, William D. Tap, Cristina R. Antonescu, Joseph P. Erinjeri, Sinchun Hwang, Sam S. Yoon, Aimee M. Crago, Edmund K. Bartlett, Samuel Singer, Travis Adamson, Evan Rosenbaum, Benjamin A. Nacev, Sujana Movva, Mary Louise Keohan, Mrinal M. Gounder, Mark A. Dickson, Ping Chi, Jason E. Chan, Viswatej Avutu, Allison L. Richards, Karissa A. Whiting, Li-Xuan Qin, Ciara M. Kelly
Representativeness of study participants.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b46c8e193737d8498c0a8ae41fad02b
https://doi.org/10.1158/1078-0432.22651624.v1
https://doi.org/10.1158/1078-0432.22651624.v1
Autor:
Samuel Singer, Chris Sander, Fumi Shima, Aimee M. Crago, Nicholas D. Socci, Evan Molinelli, Phaedra Agius, Martin L. Miller, Amanda Craig, Miguel A. López-Lago, Rachael O'Connor, Yawei Shen, Takahiro Mimae, Narasimhan Agaram, Li-Xuan Qin, Ann Y. Lee, Tomoyo Okada
Supplementary Table S1, patient characteristics. Supplementary Table S2, genes in the signature distinguishing Cluster 1 and Cluster 2. Supplementary Table S3, genes associated with disease-specific survival. Supplementary Table S4, pathway modules i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3149142109540d4ba13f568265d16541
https://doi.org/10.1158/2159-8290.22531241.v1
https://doi.org/10.1158/2159-8290.22531241.v1
Autor:
Samuel Singer, Chris Sander, Fumi Shima, Aimee M. Crago, Nicholas D. Socci, Evan Molinelli, Phaedra Agius, Martin L. Miller, Amanda Craig, Miguel A. López-Lago, Rachael O'Connor, Yawei Shen, Takahiro Mimae, Narasimhan Agaram, Li-Xuan Qin, Ann Y. Lee, Tomoyo Okada
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58098de7db26ffa1027d7dad5112faa9
https://doi.org/10.1158/2159-8290.22531247
https://doi.org/10.1158/2159-8290.22531247
Autor:
Samuel Singer, Chris Sander, Fumi Shima, Aimee M. Crago, Nicholas D. Socci, Evan Molinelli, Phaedra Agius, Martin L. Miller, Amanda Craig, Miguel A. López-Lago, Rachael O'Connor, Yawei Shen, Takahiro Mimae, Narasimhan Agaram, Li-Xuan Qin, Ann Y. Lee, Tomoyo Okada
Supplementary Figure S1, showing clustering of myxofibrosarcomas compared to normal tissue and showing the validation of the association of 5 genes with survival. Supplementary Figure S2, showing the effects of ITGA10 knockdown and overexpression. Su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f46abe18658163ba5daa5114772076b
https://doi.org/10.1158/2159-8290.22531244
https://doi.org/10.1158/2159-8290.22531244