Zobrazeno 1 - 3
of 3
pro vyhledávání: '"A. M. Bolos-Sy"'
Autor:
James A. Ferrendelli, Katherine D. Holland, Gregory C. Mathews, Keith E. Isenberg, Annabel M. Bolos-Sy, Steven M. Rothman, Douglas F. Covey
Publikováno v:
Neuron. 13:149-158
Although we now have extensive knowledge about the GABA A receptor subunits determining benzodiazepine modulation of channel function, little is known about subunits influencing other modulatory sites on the GABA A receptor-chloride channel complex.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31888a0f55e7c2f6081d602c8959a16
https://doi.org/10.1016/0896-6273(94)90465-0
https://doi.org/10.1016/0896-6273(94)90465-0
Publikováno v:
Neuropharmacology. 35(2)
The GABAA receptor/chloride ionophore (GABAR) is allosterically modulated by several classes of anticonvulsant agents, including benzodiazepines and barbiturates, and some alkyl-substituted butyrolactones. To test the hypothesis that the anticonvulsa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82862019dd4eb7af2477f4a375ee44f
https://pubmed.ncbi.nlm.nih.gov/8734480
https://pubmed.ncbi.nlm.nih.gov/8734480
Autor:
K D, Holland, G C, Mathews, A M, Bolos-Sy, J B, Tucker, P A, Reddy, D F, Covey, J A, Ferrendelli, S M, Rothman
Publikováno v:
Molecular pharmacology. 47(6)
Alkyl-substituted gamma-butyrolactones (GBLs) and gamma-thiobutyrolactones exhibit convulsant or anticonvulsant activity, depending on the alkyl substituents. alpha-Substituted lactones with small alkyl substituents are anticonvulsant and potentiate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4207cfe7299a9d486be195ea732d9466
https://pubmed.ncbi.nlm.nih.gov/7603463
https://pubmed.ncbi.nlm.nih.gov/7603463