Zobrazeno 1 - 10
of 23
pro vyhledávání: '"A. M. Bessac"'
Autor:
Anne-Dominique Degryse, Delphine Denais, Bruno Le Grand, Robert Létienne, Gareth W. John, Lydia Bel, A. M. Bessac
Publikováno v:
Fundamental and Clinical Pharmacology. 20:105-113
The cardioprotective effects of cariporide were investigated against myoglobin and troponin I elevation in a model of myocardial infarction in pig, and the possible relationship between these markers and myocardial infarct size. The left circumflex c
Autor:
A. Marty, A. M. Bessac, J. Tisne-Versailles, J. P. Rieu, J. F. Patoiseau, D. C. H. Bigg, A. Duflos, R. Bonnafous, Y. Verscheure, J. C. Tristani
Publikováno v:
European Journal of Medicinal Chemistry. 28:683-691
A series of 2,3-dihydro-4 H -1,3-benzoxazin-4-ones substituted at the 3-position with an arylalkyaminoalkyl group have been synthesized and their specific bradycardic and antiarrythmic activities evaluated. Bradycardia is optimal when the aromatic ri
Autor:
J. F. Patoiseau, D. C. H. Bigg, A. Duflos, J. C. Tristani, R. Bonnafous, J. P. Rieu, A. M. Bessac, A. Marty, Y. Verscheure, J. Tisne-Versailles
Publikováno v:
ChemInform. 25
A series of 2,3-dihydro-4 H -1,3-benzoxazin-4-ones substituted at the 3-position with an arylalkyaminoalkyl group have been synthesized and their specific bradycardic and antiarrythmic activities evaluated. Bradycardia is optimal when the aromatic ri
Publikováno v:
European journal of pharmacology. 624(1-3)
The specific persistent sodium current blocker F 15845 was tested in two myocardial ischemia-reperfusion models in the pig in order to evaluate its cardioprotective effects. In the first protocol, the left circumflex coronary artery was ligated for 6
Publikováno v:
American journal of hypertension. 10(9 Pt 1)
We explored the putative inhibitory effects of losartan, a potent nonpeptide, AT1 receptor antagonist, against thromboxane A2 (TxA2)/prostanoid (TP) receptor-mediated transcapillary shift of plasma fluid and proteins. The effects of the TP receptor a
Publikováno v:
European journal of pharmacology. 317(2-3)
We investigated the influence of endothelial nitric oxide (NO) on the pulmonary pressor activity of the stable thromboxane A2 analogue, U-46619 (9,11-dideoxy-9 alpha-(methanoepoxy) prostaglandin F2 alpha), in anesthetized open-chest Sprague-Dawley ra
Autor:
M Maffre, Francis Colpaert, F Bertolino, Jacques Maclouf, Andre Delhon, G. W. John, Sylviane Levy-Toledano, Jean-Pierre Valentin, Françoise Grelac, A. M. Bessac, Jean-Francois Patoiseau
Publikováno v:
British journal of pharmacology. 115(1)
1. We evaluated the effects of daltroban on (i) human platelet shape change and aggregation in vitro, and (ii) mean systemic and pulmonary arterial pressures (MAP and MPAP, respectively) as well as haematocrit, in anaesthetized, open-chest Sprague-Da
Publikováno v:
Methods and findings in experimental and clinical pharmacology. 17(4)
We investigated the usefulness of the pithed rat model to determine the relative potencies of 5-HT2A/2C receptor antagonists following acute intravenous and oral administration in inhibiting 5-HT-induced pressor responses. The 5-HT2A/2C receptor anta
Publikováno v:
The American journal of physiology. 268(2 Pt 2)
We investigated whether the stable thromboxane A2 (TxA2) analogue U-46619 had any direct effect on extracellular fluid partition. In anesthetized open-chest rats, U-46619 (1.25 and 20 micrograms/kg iv) dose dependently increased mean pulmonary arteri
Autor:
R. Bonnafous, J. Tisne-Versailles, C. Masse, Y. Verscheure, A. Sassine, A. M. Bessac, A. Marty
Publikováno v:
European Journal of Pharmacology. 183:799-800