Transancestral mapping and genetic load in systemic lupus erythematosus

Autor: Carl D. Langefeld, Hannah C. Ainsworth, Deborah S. Cunninghame Graham, Jennifer A. Kelly, Mary E. Comeau, Miranda C. Marion, Timothy D. Howard, Paula S. Ramos, Jennifer A. Croker, David L. Morris, Johanna K. Sandling, Jonas Carlsson Almlöf, Eduardo M. Acevedo-Vásquez, Graciela S. Alarcón, Alejandra M. Babini, Vicente Baca, Anders A. Bengtsson, Guillermo A. Berbotto, Marc Bijl, Elizabeth E. Brown, Hermine I. Brunner, Mario H. Cardiel, Luis Catoggio, Ricard Cervera, Jorge M. Cucho-Venegas, Solbritt Rantapää Dahlqvist, Sandra D’Alfonso, Berta Martins Da Silva, Iñigo de la Rúa Figueroa, Andrea Doria, Jeffrey C. Edberg, Emőke Endreffy, Jorge A. Esquivel-Valerio, Paul R. Fortin, Barry I. Freedman, Johan Frostegård, Mercedes A. García, Ignacio García de la Torre, Gary S. Gilkeson, Dafna D. Gladman, Iva Gunnarsson, Joel M. Guthridge, Jennifer L. Huggins, Judith A. James, Cees G. M. Kallenberg, Diane L. Kamen, David R. Karp, Kenneth M. Kaufman, Leah C. Kottyan, László Kovács, Helle Laustrup, Bernard R. Lauwerys, Quan-Zhen Li, Marco A. Maradiaga-Ceceña, Javier Martín, Joseph M. McCune, David R. McWilliams, Joan T. Merrill, Pedro Miranda, José F. Moctezuma, Swapan K. Nath, Timothy B. Niewold, Lorena Orozco, Norberto Ortego-Centeno, Michelle Petri, Christian A. Pineau, Bernardo A. Pons-Estel, Janet Pope, Prithvi Raj, Rosalind Ramsey-Goldman, John D. Reveille, Laurie P. Russell, José M. Sabio, Carlos A. Aguilar-Salinas, Hugo R. Scherbarth, Raffaella Scorza, Michael F. Seldin, Christopher Sjöwall, Elisabet Svenungsson, Susan D. Thompson, Sergio M. A. Toloza, Lennart Truedsson, Teresa Tusié-Luna, Carlos Vasconcelos, Luis M. Vilá, Daniel J. Wallace, Michael H. Weisman, Joan E. Wither, Tushar Bhangale, Jorge R. Oksenberg, John D. Rioux, Peter K. Gregersen, Ann-Christine Syvänen, Lars Rönnblom, Lindsey A. Criswell, Chaim O. Jacob, Kathy L. Sivils, Betty P. Tsao, Laura E. Schanberg, Timothy W. Behrens, Earl D. Silverman, Marta E. Alarcón-Riquelme, Robert P. Kimberly, John B. Harley, Edward K. Wakeland, Robert R. Graham, Patrick M. Gaffney, Timothy J. Vyse

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)

Systemic lupus erythematosus (SLE) is an autoimmune disease with a strong ethnic and gender bias. In a transancestral genetic association study, Langefeldet al. identify 24 novel regions associated with risk to lupus and propose a cumulative hits hyp

Externí odkaz: https://doaj.org/article/a68227bc3ba0457486591e4743061bf9

Síndrome de Sjögren primario y embarazo: reporte de 18 casos

Autor: Virginia Durigan, Laura Raiti, Paula Alba, Silvia Papasidero, Julia Demarchi, C. Gobbi, Diana Klajn, Alejandra M. Babini

Publikováno v: Reumatología Clínica. 15:109-112

Resumen El sindrome de Sjogren primario (SSp) afecta preferentemente al sexo femenino. Los informes sobre la evolucion de los embarazos en estas pacientes son pocos y contradictorios. Objetivo Describir las caracteristicas del embarazo y su desenlace

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::20d638377712bbc63b5611e659a462e1
https://doi.org/10.1016/j.reuma.2017.07.014

Utilidad del micofenolato de mofetilo en la nefritis lupica

Autor: Veronica Savio, Paula Alba, Alejandra M. Babini

Publikováno v: Revista de la Facultad de Ciencias Médicas de Córdoba, Vol 69, Iss 4 (2012)

Micofenolato de Mofetilo (MM) es un agente inmunosupresor que fue inicialmente usado para prevenir el rechazo en trasplante de órganos sólidos, y que luego se utilizó para tratar enfermedades autoinmunes sistémicas. En el Lupus Eritematoso Sisté

Externí odkaz: https://doaj.org/article/62ce8b869f684ad8b885505962c51f8d

271 Frequency of neonatal lupus in reference centers in the management of pregnancy and autoimmune diseases

Autor: Florencia Mollerach, Maximiliano Machado Escobar, Marina Scolnik, Belen Maria Virasoro, Maria Jose Lopez Perez, Mercedes Croce, Rosa Serrano Morales, Diana Dubinsky, Adrián Estevez, Paula Alba, Fabiola Natalia Camargo Serrudo, Cruz Lascano, María Constanza Danielsen, María de la Paz Leon, Cintia Otaduy, Laura Onetti, Cecilia Alvarez, Verónica Bellomio, Daniela Flores Rengifo, Mayra Etcheverry, V. Savio, María Hu, Marina Werner, Fernanda Guzzanti, Eduardo Kerzberg, C. Gobbi, C. Maldini, Emma E. Civit, Cecilia Pisoni, Ana M. Bertoli, Alejandra M. Babini, Verónica Saurit

Publikováno v: Abstracts.

Background Neonatal lupus (NL) is a disease in children of mothers who have specific anti-Ro/La IgG autoantibodies by passive transplacental transfer. LN is characterized by skin and cardiac involvement, as well as cytopenias, hepatic or neurological

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6592024e8e382a03b500ddfdf54736ec
https://doi.org/10.1136/lupus-2019-lsm.271

Primary Sjögren's syndrome and pregnancy: A report of 18 cases

Autor: Diana Klajn, Paula Alba, Virginia Durigan, Alejandra M. Babini, Julia Demarchi, C. Gobbi, Laura Raiti, Silvia Papasidero

Publikováno v: Reumatologia clinica. 15(2)

Primary Sjogren's syndrome (pSS) is a condition that predominantly affects women. Reports of pregnancy outcome in these patients are limited and contradictory. Objective To describe pregnancy characteristics and outcomes and newborn morbidity in wome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208e24400b35e9397f945d95f45414e0
https://pubmed.ncbi.nlm.nih.gov/28844688