Zobrazeno 1 - 10
of 140
pro vyhledávání: '"A. Lucena Cacace"'
Autor:
Miyoshi, Yutaro, Lucena-Cacace, Antonio, Tian, Yu, Matsumura, Yasuko, Tani, Kanae, Nishikawa, Misato, Narita, Megumi, Kimura, Takeshi, Ono, Koh, Yoshida, Yoshinori
Publikováno v:
In Stem Cell Reports 8 October 2024 19(10):1399-1416
Autor:
D. Otero-Albiol, J. M. Santos-Pereira, A. Lucena-Cacace, C. Clemente-González, S. Muñoz-Galvan, Y. Yoshida, A. Carnero
Publikováno v:
Cell Death and Disease, Vol 15, Iss 2, Pp 1-14 (2024)
Abstract Cellular senescence is a stress response mechanism that induces proliferative arrest. Hypoxia can bypass senescence and extend the lifespan of primary cells, mainly by decreasing oxidative damage. However, how hypoxia promotes these effects
Externí odkaz:
https://doaj.org/article/231dcca44f8d4979a44c22105929cfa8
Autor:
Julia Junghof, Yuta Kogure, Tian Yu, Eva María Verdugo-Sivianes, Megumi Narita, Antonio Lucena-Cacace, Yoshinori Yoshida
Publikováno v:
npj Regenerative Medicine, Vol 7, Iss 1, Pp 1-14 (2022)
Abstract The epicardium is a mesothelial layer covering the myocardium serving as a progenitor source during cardiac development. The epicardium reactivates upon cardiac injury supporting cardiac repair and regeneration. Fine-tuned balanced signaling
Externí odkaz:
https://doaj.org/article/40516e69d4954444b0f3718e97fb0f06
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Cardiac reactive fibrosis is a fibroblast-derived maladaptive process to tissue injury that exacerbates an uncontrolled deposition of large amounts of extracellular matrix (ECM) around cardiomyocytes and vascular cells, being recognized as a patholog
Externí odkaz:
https://doaj.org/article/b455bcf727444f8aa606bdffd3c8ea39
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-18 (2021)
Abstract Background Sarcomas are a very heterogeneous group of tumors with intrinsic developmental programs derived from the cell of origin. This implies a functional hierarchy inside tumors governed by sarcoma stem cells. Therefore, genetic and/or e
Externí odkaz:
https://doaj.org/article/dbe4cc9362e948bca2a8e6494a60bf84
Autor:
Kenji Miki, Kohei Deguchi, Misato Nakanishi-Koakutsu, Antonio Lucena-Cacace, Shigeru Kondo, Yuya Fujiwara, Takeshi Hatani, Masako Sasaki, Yuki Naka, Chikako Okubo, Megumi Narita, Ikue Takei, Stephanie C. Napier, Tsukasa Sugo, Sachiko Imaichi, Taku Monjo, Tatsuya Ando, Norihisa Tamura, Kenichi Imahashi, Tomoyuki Nishimoto, Yoshinori Yoshida
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Cardiomyocytes (CMs) derived from human induced pluripotent stem cells (hiPSCs) suffer from limited maturation. Here the authors identify ERRγ agonist as a factor that enhances cardiac morphological, metabolic, contractile and electrical maturation
Externí odkaz:
https://doaj.org/article/e591e23480c3403b95a1cc6ecca9b455
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-17 (2021)
Abstract The EMX (Empty Spiracles Homeobox) genes EMX1 and EMX2 are two homeodomain gene members of the EMX family of transcription factors involved in the regulation of various biological processes, such as cell proliferation, migration, and differe
Externí odkaz:
https://doaj.org/article/19338bc2671e4650910c425227b2f6b3
Akademický článek
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Autor:
Otero-Albiol, D., Santos-Pereira, J. M., Lucena-Cacace, A., Clemente-González, C., Muñoz-Galvan, S., Yoshida, Y., Carnero, A.
Publikováno v:
Cell Death & Disease; Feb2024, Vol. 15 Issue 2, p1-14, 14p
Autor:
Yuta Tsujisaka, Takeshi Hatani, Chikako Okubo, Ryo Ito, Azuma Kimura, Megumi Narita, Kazuhisa Chonabayashi, Shunsuke Funakoshi, Antonio Lucena-Cacace, Taro Toyoda, Kenji Osafune, Takeshi Kimura, Hirohide Saito, Yoshinori Yoshida
Publikováno v:
Stem Cell Reports. 17:1772-1785
For regenerative cell therapies using pluripotent stem cell (PSC)-derived cells, large quantities of purified cells are required. Magnetic-activated cell sorting (MACS) is a powerful approach to collect target antigen-positive cells; however, it rema