Zobrazeno 1 - 10
of 136
pro vyhledávání: '"A. Lopez-Anaya"'
Autor:
Reiter, Lawrence A., Rizzi, James P., Pandit, Jayvardan, Lasut, Michael J., McGahee, Shunda M., Parikh, Vinod D., Blake, James F., Danley, Dennis E., Laird, Ellen R., Lopez-Anaya, Arturo, Lopresti-Morrow, Lori L., Mansour, Mahmoud N., Martinelli, Gary J., Mitchell, Peter G., Owens, Brian S., Pauly, Thomas A., Reeves, Lisa M., Schulte, Gayle K., Yocum, Sue A.
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1999 9(2):127-132
Autor:
Sukhmani K. Padda, Laveena Chhatwani, Charlotte Jacobs, Lisa Zhou, Heather A. Wakelee, Arturo Lopez-Anaya
Publikováno v:
Anti-Cancer Drugs. 24:731-735
Gefitinib (an epidermal growth factor receptor tyrosine kinase inhibitor) and bexarotene (a rexinoid) affect similar oncogenic pathways and are both metabolized through cytochrome P450 CYP3A4. We studied the combination of bexarotene and gefitinib in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7874c41e4e0b33acd08f7deba2c3f2
https://doi.org/10.1097/cad.0b013e32836100d7
https://doi.org/10.1097/cad.0b013e32836100d7
Autor:
Arturo Lopez-Anaya, Petr Zatloukal, Charlotte Jacobs, Gary Middleton, Heather A. Wakelee, Desiree Hao, D. Dunlop, Natasha B. Leighl, Rodryg Ramlau
Publikováno v:
Cancer Chemotherapy and Pharmacology. 69:815-824
This is a phase I study of the retinoid X receptor agonist bexarotene (Targretin(®)) in combination with the chemotherapeutic drugs cisplatin and vinorelbine and lipid-lowering therapy. This study looked for pharmacokinetic (PK) interactions between
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e30f9c1b9ae36ea2c97d0784fc0ad05
https://doi.org/10.1007/s00280-011-1771-0
https://doi.org/10.1007/s00280-011-1771-0
Autor:
Eric K. Rowinsky, Chris H. Takimoto, Charlotte Jacobs, Arturo Lopez-Anaya, Quincy Chu, Heather A. Wakelee, J. Rodon
Publikováno v:
Cancer Chemotherapy and Pharmacology. 69:825-834
Preclinical data suggest that the synthetic retinoid bexarotene may be an effective chemopreventive agent and that it may act synergistically in combination with platinum-based chemotherapy. The primary objective of this study was to determine whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fe990020a1266c2109be2549ea816a3
https://doi.org/10.1007/s00280-011-1770-1
https://doi.org/10.1007/s00280-011-1770-1
Autor:
Marja Mergui-Roelvink, Margarita Lymboura, Arturo Lopez-Anaya, A. C. Dubbelman, Jan H.M. Schellens, Alwin D. R. Huitema, Jos H. Beijnen, Larisa Reyderman, Barbara Koetz, Hilde Rosing, Robert S. Jansen
Publikováno v:
Drug Metabolism and Disposition. 40:313-321
This mass balance study investigated the metabolism and excretion of eribulin, a nontaxane microtubule dynamics inhibitor with a novel mechanism of action, in patients with advanced solid tumors. A single approximately 2 mg (approximately 80 μCi) do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bedbbd792136d13055ff2e96b1d6d49e
https://doi.org/10.1124/dmd.111.042762
https://doi.org/10.1124/dmd.111.042762
Publikováno v:
Revista de Sanidad Militar. mar-abr1998, Vol. 52 Issue 2, p40. 5p. 2 Charts, 3 Graphs.
Autor:
Santo R. Cortina, R. J. Griffiths, Marcie L. Vaughn-Bowser, Arturo Lopez-Anaya, Lori L. Lopresti-Morrow, Kim F. McClure, Kathleen M. Donahue, Shunda M. McGahee, Mary E. Lame, Christopher S. Jones, James D. Eskra, Ralph P. Robinson, Ivan G. Otterness, Jennifer L. Liras, Matthew R. Reese, Lisa M. Tobiassen, Sue A. Yocum, Gary J. Martinelli, Peter G. Mitchell, Lawrence A. Reiter, Marcia L. Bliven
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:3389-3395
The SAR of a series of sterically hindered sulfonamide hydroxamic acids with relatively large P1' groups is described. The compounds typically spare MMP-1 while being potent inhibitors of MMP-13. The metabolically more stable compounds in the series
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf1b568cb8f74bdeb9c13de17634182
https://doi.org/10.1016/j.bmcl.2004.04.083
https://doi.org/10.1016/j.bmcl.2004.04.083
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 19:1277-1289
A sensitive, reproducible and rapid HPLC assay was developed for preformulation and stability studies of a potential radioprotector, S-2-(3-methylaminopropylamino) ethyl-phosphorothioate, WR-3689. This method is based on the elution of WR3689 by high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16d5cd0921913a19668dd592c8a7256d
https://doi.org/10.1080/10826079608006318
https://doi.org/10.1080/10826079608006318
Publikováno v:
Scopus-Elsevier
Sustained release biodegradable microcapsules of AZT were prepared using different concentrations of copolymer of poly(lactic/glycolic) acid (PLGA 50:50 and PLGA 90:10). Solid microcapsules were collected following the complete evaporation of the sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3caf563a8b632e9b9e573c7bd269fdf3
https://doi.org/10.3109/02652049609026014
https://doi.org/10.3109/02652049609026014
Publikováno v:
Biological Trace Element Research. 40:161-176
The effect of nutritional copper (Cu) deficiency on the antiinflammatory activity and pharmacokinetics of aspirin (ASA) was investigated in rats. Male, weanling Sprague-Dawley rats were fed either a Cu-deficient (CuD) or Cu-sufficient (CuS) diet for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02bb9298bbc8f1bf7bfb7231ca0b013
https://doi.org/10.1007/bf02950789
https://doi.org/10.1007/bf02950789