Zobrazeno 1 - 10
of 286
pro vyhledávání: '"A. Liffers"'
Autor:
Laura K. Godfrey, Jan Forster, Sven-Thorsten Liffers, Christopher Schröder, Johannes Köster, Leonie Henschel, Kerstin U. Ludwig, David Lähnemann, Marija Trajkovic-Arsic, Diana Behrens, Aldo Scarpa, Rita T. Lawlor, Kathrin E. Witzke, Barbara Sitek, Steven A. Johnsen, Sven Rahmann, Bernhard Horsthemke, Michael Zeschnigk, Jens T. Siveke
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-22 (2024)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with poor prognosis. It is marked by extraordinary resistance to conventional therapies including chemotherapy and radiation, as well as to essentially all targeted t
Externí odkaz:
https://doaj.org/article/d600d9b4f409474cb363cc7b8d335cf3
Autor:
Mavroeidi, I.-A., Burghofer, J., Kalbourtzis, S., Taghizadeh, H., Webersinke, G., Piringer, G., Kasper, S., Schreil, G., Liffers, S.T., Reichinger, A., Kirchweger, P., Heibl, S., Hamacher, R., Schmitt, C.A., Schuler, M., Prager, G.W., Kersting, D., Treckmann, J., Schildhaus, H.-U., Rumpold, H., Siveke, J.T., Doleschal, B.
Publikováno v:
In ESMO Open August 2024 9(8)
Autor:
Timm M. Reissig, Swetlana Ladigan‐Badura, Anja Steinberg, Abdelouahid Maghnouj, Ting Li, Berlinda Verdoodt, Sven T. Liffers, Michael Pohl, Heiner Wolters, Christian Teschendorf, Richard Viebahn, Jakob Admard, Nicolas Casadei, Andrea Tannapfel, Wolff Schmiegel, Stephan A. Hahn, Deepak B. Vangala
Publikováno v:
Molecular Oncology, Vol 17, Iss 11, Pp 2396-2414 (2023)
Although approximately half of all metastatic colorectal cancers (mCRCs) harbour mutations in KRAS or NRAS, hardly any progress has been made regarding targeted treatment for this group over the last few years. Here, we investigated the efficacy of v
Externí odkaz:
https://doaj.org/article/43b89c56d838488bb188749e4ab6758c
Autor:
Zaun, Gregor, Borchert, Sabrina, Metzenmacher, Martin, Lueong, Smiths, Wiesweg, Marcel, Zaun, Yasmin, Pogorzelski, Michael, Behrens, Franziska, Schildhaus, Hans-Ulrich, Virchow, Isabel, Kasper, Stefan, Schuler, Martin, Theurer, Sarah, Liffers, Sven
Publikováno v:
In European Journal of Cancer March 2024 200
Autor:
Reissig, T.M., Tzianopoulos, I., Liffers, S.-T., Rosery, V.K., Guyot, M., Ting, S., Wiesweg, M., Kasper, S., Meister, P., Herold, T., Schmidt, H.H., Schumacher, B., Albers, D., Markus, P., Treckmann, J., Schuler, M., Schildhaus, H.-U., Siveke, J.T.
Publikováno v:
In ESMO Open June 2023 8(3)
Autor:
Irina Heid, Corinna Münch, Sinan Karakaya, Smiths S. Lueong, Alina M. Winkelkotte, Sven T. Liffers, Laura Godfrey, Phyllis F. Y. Cheung, Konstantinos Savvatakis, Geoffrey J. Topping, Florian Englert, Lukas Kritzner, Martin Grashei, Andrea Tannapfel, Richard Viebahn, Heiner Wolters, Waldemar Uhl, Deepak Vangala, Esther M. M. Smeets, Erik H. J. G. Aarntzen, Daniel Rauh, Wilko Weichert, Jörg D. Hoheisel, Stephan A. Hahn, Franz Schilling, Rickmer Braren, Marija Trajkovic-Arsic, Jens T. Siveke
Publikováno v:
Cancer & Metabolism, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) lacks effective treatment options beyond chemotherapy. Although molecular subtypes such as classical and QM (quasi-mesenchymal)/basal-like with transcriptome-based distinct signatures have b
Externí odkaz:
https://doaj.org/article/bde08f1443834615a3f9cb25e23e0e2b
Akademický článek
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Autor:
Lorenzen, Sylvie, Quante, Michael, Rauscher, Isabel, Slotta-Huspenina, Julia, Weichert, Wilko, Feith, Marcus, Friess, Helmut, Combs, Stefanie E., Weber, Wolfgang A., Haller, Bernhard, Angele, Martin, Albertsmeier, Markus, Blankenstein, Christiane, Kasper, Stefan, Schmid, Roland M., Bassermann, Florian, Schwaiger, Markus, Liffers, Sven-Thorsten, Siveke, Jens T.
Publikováno v:
In European Journal of Cancer November 2022 175:99-106
Autor:
Phyllis F. Cheung, JiaJin Yang, Rui Fang, Arianna Borgers, Kirsten Krengel, Anne Stoffel, Kristina Althoff, Chi Wai Yip, Elaine H. L. Siu, Linda W. C. Ng, Karl S. Lang, Lamin B. Cham, Daniel R. Engel, Camille Soun, Igor Cima, Björn Scheffler, Jana K. Striefler, Marianne Sinn, Marcus Bahra, Uwe Pelzer, Helmut Oettle, Peter Markus, Esther M. M. Smeets, Erik H. J. G. Aarntzen, Konstantinos Savvatakis, Sven-Thorsten Liffers, Smiths S. Lueong, Christian Neander, Anna Bazarna, Xin Zhang, Annette Paschen, Howard C. Crawford, Anthony W. H. Chan, Siu Tim Cheung, Jens T. Siveke
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Immune responses to pancreatic ductal adenocarcinoma can be inhibited by cancer cells. Here the authors show that high levels of progranulin in PDAC inhibits immune responses by reducing MHC class I antigen presentation through enhanced degradation o
Externí odkaz:
https://doaj.org/article/c9aa189db2194c2eba13f30f461a6fdd
Autor:
Dorsch, Madeleine, Kowalczyk, Manuela, Planque, Mélanie, Heilmann, Geronimo, Urban, Sebastian, Dujardin, Philip, Forster, Jan, Ueffing, Kristina, Nothdurft, Silke, Oeck, Sebastian, Paul, Annika, Liffers, Sven T., Kaschani, Farnusch, Kaiser, Markus, Schramm, Alexander, Siveke, Jens T., Winslow, Monte M., Fendt, Sarah-Maria, Nalbant, Perihan, Grüner, Barbara M.
Publikováno v:
In Cell Reports 23 November 2021 37(8)