Zobrazeno 1 - 10
of 3 877
pro vyhledávání: '"A. Laster"'
Autor:
James A. Hendrixson, Alicen James, Nisreen S. Akel, Dominique J. Laster, Julie A. Crawford, Stuart B. Berryhill, Melda Onal
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 3, Pp 73-84 (2024)
Abstract Chaperone‐mediated autophagy (CMA) is a lysosome‐dependent degradation pathway that eliminates proteins that are damaged, partially unfolded, or targeted for selective proteome remodeling. CMA contributes to several cellular processes, i
Externí odkaz:
https://doaj.org/article/04666c39eed746e8abebce47d4e95d82
Autor:
Kylene P. Daily, Asmaa Badr, Mostafa Eltobgy, Shady Estfanous, Owen Whitham, Michelle H. Tan, Cierra Carafice, Kathrin Krause, Andrew McNamara, Kaitlin Hamilton, Samuel Houle, Spandan Gupta, Gauruv A. Gupta, Shruthi Madhu, Julie Fitzgerald, Abbey A. Saadey, Brooke Laster, Pearlly Yan, Amy Webb, Xiaoli Zhang, Maciej Pietrzak, Olga N. Kokiko-Cochran, Hazem E. Ghoneim, Amal O. Amer
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-20 (2024)
Abstract Alzheimer’s disease (AD) is the sixth leading cause of death in the USA. It is established that neuroinflammation contributes to the synaptic loss, neuronal death, and symptomatic decline of AD patients. Accumulating evidence suggests a cr
Externí odkaz:
https://doaj.org/article/e9004d48993349bc9f739f58c680a79a
Autor:
Zhao, Ran, Yin, Fanxiang, Fredimoses, Mangaladoss, Zhao, Jianhua, Fu, Xiaorong, Xu, Beibei, Liang, Mengrui, Chen, Hanyong, Liu, Kangdong, Lei, Mingjuan, Laster, Kyle Vaughn, Li, Zhi, Kundu, Joydeb Kumar, Dong, Zigang, Lee, Mee-Hyun
Publikováno v:
In Phytomedicine July 2024 129
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-34 (2023)
Abstract The RAS/mitogen-activated protein kinase (MAPK) signaling cascade is commonly dysregulated in human malignancies by processes driven by RAS or RAF oncogenes. Among the members of the RAF kinase family, CRAF plays an important role in the RAS
Externí odkaz:
https://doaj.org/article/d125e847832a4435a5db541aafe5edfc
Autor:
Spierer, Abraham, Wygnanski-Jaffe, Tamara, Zitzer, Nethanel, Cohen, Dan, Shpigelman, Ahuva, Hadash, Maoz, Ortenberg, Ilya, Cohen, Rinat, Leib, Hana, Arow, Majd, Parness, Reut, Rodov, Luba, Goz, Alexandra, Katz, Haia, Bazov, Anabel, Nissen, Chaim, Avraham, Gabriel, Borsha, Emad, Keynann, Idit, Aviv, Tali, Corcos, Nathalie, Roll, Keren, Mezer, Eedy, Brucker, Vered, Abecassis, Meital, Rabinovich, Ronen, Laster, Eran, Politi, Ronit, Givoni, Hila, Amitirat, Ahed, Barrett, Chiya Robert, Zioni, Adelina, Kuperman, Katty, Crocos, Yael, Moshkovitz, Avital, Kushner, Burton J., Belkin, Michael, Yehezkel, Oren
Publikováno v:
In American Journal of Ophthalmology June 2024 262:199-205
Publikováno v:
Military Review. May/Jun2024, Vol. 104 Issue 3, p34-49. 16p.
Autor:
Xuechao Jia, Penglei Wang, Chuntian Huang, Dengyun Zhao, Qiong wu, Bingbing Lu, Wenna Nie, Limeng Huang, Xueli Tian, Pan li, Kyle Vaughn Laster, Yanan Jiang, Xiang Li, Honglin Li, Zigang Dong, Kangdong Liu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-20 (2023)
Abstract Background Although molecular targets such as HER2, TP53 and PIK3CA have been widely studied in esophageal cancer, few of them were successfully applied for clinical treatment. Therefore, it is urgent to discover novel actionable targets and
Externí odkaz:
https://doaj.org/article/a72f087081d1441b9e1777f2df0222b5
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-25 (2023)
Abstract The CLKs (Cdc2-like kinases) belong to the dual-specificity protein kinase family and play crucial roles in regulating transcript splicing via the phosphorylation of SR proteins (SRSF1–12), catalyzing spliceosome molecular machinery, and m
Externí odkaz:
https://doaj.org/article/1077b63702114c29a2a0d54848eae720
Autor:
Laster, Dominique J., Akel, Nisreen S., Hendrixson, James A., James, Alicen, Crawford, Julie A., Fu, Qiang, Berryhill, Stuart B., Thostenson, Jeff D., Nookaew, Intawat, O’Brien, Charles A., Onal, Melda
Publikováno v:
In iScience 18 August 2023 26(8)
Publikováno v:
In The Pediatric Clinics of North America August 2023 70(4):725-743