Higher-order effects in the dynamics of hierarchical triple systems. II. Second-order and dotriacontapole-order effects

Autor: Conway, Landen, Will, Clifford M.

Publikováno v: Phys. Rev. D 110, 083022 (2024)

We analyze the long-term evolution of hierarchical triple systems in Newtonian gravity to second order in the quadrupolar perturbation parameter, and to sixth order in $\epsilon = a/A$, the ratio of the semimajor axes of the inner and outer orbits. W

Externí odkaz: http://arxiv.org/abs/2408.04411

Epigenetic memory of radiotherapy in dermal fibroblasts impairs wound repair capacity in cancer survivors

Autor: Xiaowei Bian, Minna Piipponen, Zhuang Liu, Lihua Luo, Jennifer Geara, Yongjian Chen, Traimate Sangsuwan, Monica Maselli, Candice Diaz, Connor A. Bain, Evelien Eenjes, Maria Genander, Michael Crichton, Jenna L. Cash, Louis Archambault, Siamak Haghdoost, Julie Fradette, Pehr Sommar, Martin Halle, Ning Xu Landén

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)

Abstract Radiotherapy (RT), a common cancer treatment, unintentionally harms surrounding tissues, including the skin, and hinders wound healing years after treatment. This study aims to understand the mechanisms behind these late-onset adverse effect

Externí odkaz: https://doaj.org/article/effdd052ea744da69203c471c4031c14

The lncRNA SNHG26 drives the inflammatory-to-proliferative state transition of keratinocyte progenitor cells during wound healing

Autor: Dongqing Li, Zhuang Liu, Letian Zhang, Xiaowei Bian, Jianmin Wu, Li Li, Yongjian Chen, Lihua Luo, Ling Pan, Lingzhuo Kong, Yunting Xiao, Jiating Wang, Xiya Zhang, Wang Wang, Maria Toma, Minna Piipponen, Pehr Sommar, Ning Xu Landén

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)

Abstract The cell transition from an inflammatory phase to a subsequent proliferative phase is crucial for wound healing, yet the driving mechanism remains unclear. By profiling lncRNA expression changes during human skin wound healing and screening

Externí odkaz: https://doaj.org/article/b5ba186c81e04db7a2a0131001bf4e99

Platform for Probing Radiation Transport Properties of Hydrogen at Conditions Found in the Deep Interiors of Red Dwarfs

Autor: Lütgert, J., Bethkenhagen, M., Bachmann, B., Divol, L., Gericke, D. O., Glenzer, S. H., Hall, G. N., Izumi, N., Khan, S. F., Landen, O. L., MacLaren, S. A., Masse, L., Redmer, R., Schörner, M., Schölmerich, M. O., Schumacher, S., Shaffer, N. R., Starrett, C. E., Sterne, P. A., Trosseille, C., Döppner, T., Kraus, D.

Publikováno v: Physics of Plasmas 29, 083301 (2022)

We describe an experimental concept at the National Ignition Facility for specifically tailored spherical implosions to compress hydrogen to extreme densities (up to $\sim$800$\times$ solid density, electron number density n$_e$$\sim$4$\times$10$^{25

Externí odkaz: http://arxiv.org/abs/2301.08610

Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study

Autor: Anna H. Ou, Sara B. Rosenthal, Mazda Adli, Kazufumi Akiyama, Nirmala Akula, Martin Alda, Azmeraw T. Amare, Raffaella Ardau, Bárbara Arias, Jean-Michel Aubry, Lena Backlund, Michael Bauer, Bernhard T. Baune, Frank Bellivier, Antonio Benabarre, Susanne Bengesser, Abesh Kumar Bhattacharjee, Joanna M. Biernacka, Pablo Cervantes, Guo-Bo Chen, Hsi-Chung Chen, Caterina Chillotti, Sven Cichon, Scott R. Clark, Francesc Colom, David A. Cousins, Cristiana Cruceanu, Piotr M. Czerski, Clarissa R. Dantas, Alexandre Dayer, Maria Del Zompo, Franziska Degenhardt, J. Raymond DePaulo, Bruno Étain, Peter Falkai, Frederike Tabea Fellendorf, Ewa Ferensztajn-Rochowiak, Andreas J. Forstner, Louise Frisén, Mark A. Frye, Janice M. Fullerton, Sébastien Gard, Julie S. Garnham, Fernando S. Goes, Maria Grigoroiu-Serbanescu, Paul Grof, Oliver Gruber, Ryota Hashimoto, Joanna Hauser, Urs Heilbronner, Stefan Herms, Per Hoffmann, Andrea Hofmann, Liping Hou, Stephane Jamain, Esther Jiménez, Jean-Pierre Kahn, Layla Kassem, Tadafumi Kato, Sarah Kittel-Schneider, Barbara König, Po-Hsiu Kuo, Ichiro Kusumi, Nina Lackner, Gonzalo Laje, Mikael Landén, Catharina Lavebratt, Marion Leboyer, Susan G. Leckband, Carlos A. López Jaramillo, Glenda MacQueen, Mario Maj, Mirko Manchia, Cynthia Marie-Claire, Lina Martinsson, Manuel Mattheisen, Michael J. McCarthy, Susan L. McElroy, Francis J. McMahon, Philip B. Mitchell, Marina Mitjans, Francis M. Mondimore, Palmiero Monteleone, Caroline M. Nievergelt, Markus M. Nöthen, Tomas Novák, Urban Ösby, Norio Ozaki, Sergi Papiol, Roy H. Perlis, Claudia Pisanu, James B. Potash, Andrea Pfennig, Daniela Reich-Erkelenz, Andreas Reif, Eva Z. Reininghaus, Marcella Rietschel, Guy A. Rouleau, Janusz K. Rybakowski, Martin Schalling, Peter R. Schofield, K. Oliver Schubert, Thomas G. Schulze, Barbara W. Schweizer, Florian Seemüller, Giovanni Severino, Tatyana Shekhtman, Paul D. Shilling, Kazutaka Shimoda, Christian Simhandl, Claire M. Slaney, Alessio Squassina, Thomas Stamm, Pavla Stopkova, Sarah K. Tighe, Alfonso Tortorella, Gustavo Turecki, Eduard Vieta, Julia Volkert, Stephanie Witt, Naomi R. Wray, Adam Wright, L. Trevor Young, Peter P. Zandi, John R. Kelsoe

Publikováno v: Translational Psychiatry, Vol 14, Iss 1, Pp 1-9 (2024)

Abstract Lithium is the gold standard treatment for bipolar disorder (BD). However, its mechanism of action is incompletely understood, and prediction of treatment outcomes is limited. In our previous multi-omics study of the Pharmacogenomics of Bipo

Externí odkaz: https://doaj.org/article/4ffae4e761e24f54b9836464e5e374c0