Lattice Boltzmann study of evaporation phenomena

Autor: Laghezza, G

Evaporation phenomena are having a resurgent interest in the recent years thanks to new techniques that allow for better flow visualization and microfabrication techniques of surfaces with interesting wetting properties. From the theoretical point of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1064::a26fd12935f9aada1a9dae906a6bdb2b
https://ora.ox.ac.uk/objects/uuid:ddab7a63-09d8-4fa7-bc87-577be6333091

Structural Insight into Peroxisome Proliferator-Activated Receptor ³ Binding of Two Ureidofibrate-Like Enantiomers by Molecular Dynamics, Cofactor Interaction Analysis, and Site-Directed Mutagenesis

Autor: G. Pochetti (a), N. Mitro (b, A. Lavecchia (d), F. Gilardi (b, N. Besker (e), E. Scotti (b, M. Aschi (f), N. Re (e), G. Fracchiolla (g), A. Laghezza (g), P. Tortorella (g), R. Montanari (a), E. Novellino (d), F. Mazza (a, M. Crestani (b), F. Loiodice (g)

Publikováno v: Journal of medicinal chemistry 53 (2010): 4354–4366. doi:10.1021/jm9013899
info:cnr-pdr/source/autori:G. Pochetti (a), N. Mitro (b,c), A. Lavecchia (d), F. Gilardi (b,h), N. Besker (e), E. Scotti (b,i), M. Aschi (f), N. Re (e), G. Fracchiolla (g), A. Laghezza (g), P. Tortorella (g), R. Montanari (a), E. Novellino (d), F. Mazza (a,l), M. Crestani (b) and F. Loiodice (g)/titolo:Structural Insight into Peroxisome Proliferator-Activated Receptor ³ Binding of Two Ureidofibrate-Like Enantiomers by Molecular Dynamics, Cofactor Interaction Analysis, and Site-Directed Mutagenesis/doi:10.1021%2Fjm9013899/rivista:Journal of medicinal chemistry/anno:2010/pagina_da:4354/pagina_a:4366/intervallo_pagine:4354–4366/volume:53

Molecular dynamics simulations were performed on two ureidofibrate-like enantiomers to gain insight into their different potency and efficacy against PPAR³. The partial agonism of the S enantiomer seems to be due to its capability to stabilize diffe

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http://www.cnr.it/prodotto/i/19849