Zobrazeno 1 - 10
of 548
pro vyhledávání: '"A. Labbadia"'
Autor:
Annmary Paul Erinjeri, Xunyan Wang, Rhianna Williams, Riccardo Zenezini Chiozzi, Konstantinos Thalassinos, Johnathan Labbadia
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Increased activity of the heat shock factor, HSF-1, suppresses proteotoxicity and enhances longevity. However, the precise mechanisms by which HSF-1 promotes lifespan are unclear. Using an RNAi screen, we identify ubiquilin-1 (ubql-1) as an
Externí odkaz:
https://doaj.org/article/7a2b04bcfb114f56b65bf5fb9e168879
Autor:
Nikolaos Tataridas-Pallas, Yahyah Aman, Rhianna Williams, Hannah Chapman, Kevin J.H. Cheng, Casandra Gomez-Paredes, Gillian P. Bates, John Labbadia
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109834- (2024)
Summary: Fasting has emerged as a potent means of preserving tissue function with age in multiple model organisms. However, our understanding of the relationship between food removal and long-term health is incomplete. Here, we demonstrate that in th
Externí odkaz:
https://doaj.org/article/1deb778c55b54bd2bbaa49035a536ea2
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The proteostasis network (PN) is a collection of protein folding and degradation pathways that spans cellular compartments and acts to preserve the integrity of the proteome. The differential expression of PN genes is a hallmark of many canc
Externí odkaz:
https://doaj.org/article/b46c119981a34eda91847ebac7680848
Autor:
Irene Serrano-Gonzalo, Laura López de Frutos, Carlos Lahoz-Gil, Francisco Delgado-Mateos, María Ángeles Fernández-Galán, Montserrat Morales-Conejo, María Victoria Calle-Gordo, Daiana Ibarretxe-Gerediaga, Andrés Madinaveitia-Ochoa, Antonio Albarracin-Arraigosa, José Balanzat-Muñoz, Patricia Correcher-Medina, Luis Javier García-Frade, Jesús María Hernández-Rivas, Francesca Labbadia, Jesus Miguel López-Dupla, María Luisa Lozano-Almela, Elvira Mora-Casterá, María Soledad Noya-Pereira, María Ángeles Ruíz-Guinaldo, María del Mar Tormo-Díaz, Isidro Vitoria-Miñana, Isidro Arévalo-Vargas, Marcio Andrade-Campos, Pilar Giraldo
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-12 (2023)
Abstract Background The availability of multiple treatments for type 1 Gaucher disease increases the need for real-life studies to evaluate treatment efficacy and safety and provide clinicians with more information to choose the best personalized the
Externí odkaz:
https://doaj.org/article/117cc15479cb4170b8e7211100fa9146
Autor:
Tataridas-Pallas, Nikolaos, Aman, Yahyah, Williams, Rhianna, Chapman, Hannah, Cheng, Kevin J.H., Gomez-Paredes, Casandra, Bates, Gillian P., Labbadia, John
Publikováno v:
In iScience 21 June 2024 27(6)
Autor:
Johnathan Labbadia
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
The ability to respond rapidly and efficiently to protein misfolding is crucial for development, reproduction and long-term health. Cells respond to imbalances in cytosolic/nuclear protein homeostasis through the Heat Shock Response, a tightly regula
Externí odkaz:
https://doaj.org/article/5454a2dd507746439ae7dcf3b0729db2
Autor:
Gabriella Bottari, Isabella Guzzo, Andrea Cappoli, Raffaella Labbadia, Salvatore Perdichizzi, Carmela Serpe, Jacques Creteur, Corrado Cecchetti, Fabio Silvio Taccone
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
BackgroundThere is a lack of data to support the use of hemoadsorption in pediatric septic shock. The aim of our study was to assess the effectiveness and safety of CytoSorb therapy in this setting.MethodsPhase II interventional single arm pilot stud
Externí odkaz:
https://doaj.org/article/553badfa9b1f4e878d4cdb6932370f30
Autor:
Aman, Yahyah, Erinjeri, Annmary Paul, Tataridas-Pallas, Nikolaos, Williams, Rhianna, Wellman, Rachel, Chapman, Hannah, Labbadia, John
Publikováno v:
In Cell Reports 22 November 2022 41(8)
Autor:
Cappoli, Andrea1 andrea.cappoli@opbg.net, Labbadia, Raffaella1, Antonucci, Luca1, Bottari, Gabriella2, Rossetti, Emanuele3, Guzzo, Isabella1
Publikováno v:
Pediatric Nephrology. Nov2023, Vol. 38 Issue 11, p3835-3844. 10p. 1 Diagram, 2 Charts, 5 Graphs.
Autor:
Erinjeri, Annmary Paul, Wang, Xunyan, Williams, Rhianna, Chiozzi, Riccardo Zenezini, Thalassinos, Konstantinos, Labbadia, Johnathan
Publikováno v:
Nature Communications; 11/12/2024, Vol. 15 Issue 1, p1-15, 15p