Zobrazeno 1 - 10
of 152
pro vyhledávání: '"A. L. Vanden Hoek"'
Autor:
Matt T. Oberdier, Jing Li, Daniel I. Ambinder, Masahito Suzuki, Ethan Tumarkin, Sarah Fink, Luca Neri, Xiangdong Zhu, Cody N. Justice, Terry L. Vanden Hoek, Henry R. Halperin
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 13 (2024)
Background Outcomes from cardiopulmonary resuscitation (CPR) following sudden cardiac arrest are suboptimal. Postresuscitation targeted temperature management has been shown to have benefit in subjects with sudden cardiac arrest due to ventricular fi
Externí odkaz:
https://doaj.org/article/e5b5001e241e49edadd1bff180471eef
Autor:
Jing Li, Xiangdong Zhu, Matt T. Oberdier, Chunpei Lee, Shaoxia Lin, Sarah J. Fink, Cody N. Justice, Kevin Qin, Andrew W. Begeman, Frederick C. Damen, Hajwa Kim, Jiwang Chen, Kejia Cai, Henry R. Halperin, Terry L. Vanden Hoek
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 9 (2023)
Out-of-hospital cardiac arrest is a leading cause of death in the US, with a mortality rate over 90%. Preclinical studies demonstrate that cooling during cardiopulmonary resuscitation (CPR) is highly beneficial, but can be challenging to implement cl
Externí odkaz:
https://doaj.org/article/21e1ed80f0e04c6797c226e941845f6f
Publikováno v:
Physiological Reports, Vol 11, Iss 4, Pp n/a-n/a (2023)
Abstract Therapeutic hypothermia (TH) provides cardioprotection from ischemia/reperfusion (I/R) injury. However, it remains unknown how TH regulates metabolic recovery. We tested the hypothesis that TH modulates PTEN, Akt, and ERK1/2, and improves me
Externí odkaz:
https://doaj.org/article/a926a8ff2e104583b748df1002f6ff5d
Autor:
Xiangdong Zhu, Jing Li, Huashan Wang, Filip M Gasior, Chunpei Lee, Shaoxia Lin, Cody N Justice, J Michael O'Donnell, Terry L Vanden Hoek
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0291598 (2023)
Metabolic suppression in the ischemic heart is characterized by reduced levels of NAD+ and ATP. Since NAD+ is required for most metabolic processes that generate ATP, we hypothesized that nicotinamide restores ischemic tissue NAD+ and improves cardia
Externí odkaz:
https://doaj.org/article/124fc3e958eb4cf4adf3cb65cef46c82
Autor:
Dylan M. Richards, MacKenzie J. Tweardy, Steven R. Steinhubl, David W. Chestek, Terry L. Vanden Hoek, Karen A. Larimer, Stephan W. Wegerich
Publikováno v:
npj Digital Medicine, Vol 4, Iss 1, Pp 1-11 (2021)
Abstract The COVID-19 pandemic has accelerated the adoption of innovative healthcare methods, including remote patient monitoring. In the setting of limited healthcare resources, outpatient management of individuals newly diagnosed with COVID-19 was
Externí odkaz:
https://doaj.org/article/2d633c5dcb0849869d647f1547a21803
Autor:
Jing Li, Xiangdong Zhu, Huashan Wang, Chunpei Lee, Sy-Jou Chen, Yuanyu Qian, Mei Han, Ryan Bunney, David G Beiser, Terry L Vanden Hoek
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0220604 (2019)
Therapeutic hypothermia initiated during cardiopulmonary resuscitation (CPR) in pre-clinical studies appears to be highly protective against sudden cardiac arrest injury. Given the challenges to implementing CPR cooling clinically, insights into its
Externí odkaz:
https://doaj.org/article/dd6beae96cd34a1d89c0ccdc3267e2fb
Autor:
Jing, Li, Wei-Tien, Chang, Gina, Qin, Kimberly R, Wojcik, Chang-Qing, Li, Chin-Wang, Hsu, Mei, Han, Xiangdong, Zhu, Terry L, Vanden Hoek, Zuo-Hui, Shao
Publikováno v:
The American Journal of Chinese Medicine. 50:1255-1267
Preconditioning has a powerful protective potential against myocardial ischemia-reperfusion injury (I/R). Our prior work demonstrated that baicalein, a flavonoid derived from the root of Scatellaria baicalensis Georgi (also known as Huangqin), confer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f102c734251f04b4a28f2ee2ebe0ad53
https://doi.org/10.1142/s0192415x22500513
https://doi.org/10.1142/s0192415x22500513
Publikováno v:
Physiological Reports. 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59b79e93305f5ab199d0c1cfb9759e7d
https://doi.org/10.14814/phy2.15611
https://doi.org/10.14814/phy2.15611
Publikováno v:
Resuscitation. 182:109671
Extracorporeal cardiopulmonary resuscitation (eCPR) is emerging as an effective, lifesaving resuscitation strategy for select patients with prolonged or refractory cardiac arrest. Currently, a paucity of evidence-based recommendations is available to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6be275b63f3b9b1f35bb8fc5aa6dad4
https://doi.org/10.1016/j.resuscitation.2022.12.009
https://doi.org/10.1016/j.resuscitation.2022.12.009
Autor:
Jing Li, Xiangdong Zhu, Matt Oberdier, Chunpei Lee, Misha Granado, Sarah Fink, Shaoxia Lin, Kevin Qin, CODY JUSTICE, Hajwa Kim, Frederick Damen, Kejia Cai, Pratik B Doshi, Henry Wang, Henry R Halperin, Terry L Vanden Hoek
Publikováno v:
Circulation. 144
Introduction: While effective for out-of-hospital cardiac arrest, therapeutic hypothermia can be difficult to timely implement clinically. No drugs exist for improving neurologically intact survival. We have developed a novel peptide (TAT-PHLPP) that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b5dc0bf978fe1644d1e7d24ebe0c72a
https://doi.org/10.1161/circ.144.suppl_2.11243
https://doi.org/10.1161/circ.144.suppl_2.11243