Zobrazeno 1 - 8
of 8
pro vyhledávání: '"A. L. Sivkina"'
Publikováno v:
Успехи молекулярной онкологии, Vol 10, Iss 2, Pp 30-41 (2023)
Genetic apparatus of human cells is constantly affected by a broad spectrum of mutagenic factors, both exogenous and endogenous. Genetic and epigenetic disorders, which emerge as a result of this influence, become the main cause of the majority of ma
Externí odkaz:
https://doaj.org/article/afaf993f0c09406297b6ebe7ff848498
Autor:
Anastasiia L. Sivkina, Maria G. Karlova, Maria E. Valieva, Laura L. McCullough, Timothy Formosa, Alexey K. Shaytan, Alexey V. Feofanov, Mikhail P. Kirpichnikov, Olga S. Sokolova, Vasily M. Studitsky
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
Sivkina et al. present a biochemical and biophysical characterization of the interaction of S. cerevisiae histone chaperone FACT with the nucleosome core particle. They show that FACT adopts a more open geometry in the presence of Nhp6, and together
Externí odkaz:
https://doaj.org/article/a6b17f84681e4269915f8db9da80afb0
Autor:
Olesya I. Volokh, Anastasia L. Sivkina, Andrey V. Moiseenko, Anna V. Popinako, Maria G. Karlova, Maria E. Valieva, Elena Y. Kotova, Mikhail P. Kirpichnikov, Timothy Formosa, Vasily M. Studitsky, Olga S. Sokolova
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Human FACT (FACT) is a multifunctional histone chaperone involved in transcription, replication and DNA repair. Curaxins are anticancer compounds that induce FACT-dependent nucleosome unfolding and trapping of FACT in the chromatin of cancer cells (c
Externí odkaz:
https://doaj.org/article/c3e88a4384e64cfd8196406fe7b52a80
Autor:
Daria K. Malinina, Anastasiia L. Sivkina, Anna N. Korovina, Laura L. McCullough, Tim Formosa, Mikhail P. Kirpichnikov, Vasily M. Studitsky, Alexey V. Feofanov
Publikováno v:
Cells, Vol 11, Iss 19, p 2931 (2022)
Yeast Hmo1 is a high mobility group B (HMGB) protein that participates in the transcription of ribosomal protein genes and rDNA, and also stimulates the activities of some ATP-dependent remodelers. Hmo1 binds both DNA and nucleosomes and has been pro
Externí odkaz:
https://doaj.org/article/08f01f7b34af4d3596c3feeea2140fa3
Publikováno v:
International Journal of Biomedicine, Vol 11, Iss Suppl_1, Pp 14-15 (2021)
Background: DNA accessibility in chromatin is important for proper gene expression and is regulated by multiple factors. One of them is histone chaperone FACT, which conducts large-scale ATP-independent nucleosome unfolding that increases the accessi
Externí odkaz:
https://doaj.org/article/dac69e17eed24b7093b006562edbf0ce
Publikováno v:
Moscow University Biological Sciences Bulletin. 76:191-195
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6198ac3ae9502b74f2c959a9b54db2bc
https://doi.org/10.3103/s009639252104012x
https://doi.org/10.3103/s009639252104012x
Autor:
Tatyana V, Andreeva, Natalya V, Maluchenko, Anastasiia L, Sivkina, Oleg V, Chertkov, Maria E, Valieva, Elena Y, Kotova, Mikhail P, Kirpichnikov, Vasily M, Studitsky, Alexey V, Feofanov
Publikováno v:
Microsc Microanal
Inorganic ions are essential factors stabilizing nucleosome structure; however, many aspects of their effects on DNA transactions in chromatin remain unknown. Here, differential effects of K(+) and Na(+) on the nucleosome structure, stability, and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7c3ea357aad9f56656b730a74089277
https://pubmed.ncbi.nlm.nih.gov/35177143
https://pubmed.ncbi.nlm.nih.gov/35177143
Autor:
Anastasiia L. Sivkina, Maria G. Karlova, Maria E. Valieva, Laura L. McCullough, Timothy Formosa, Alexey K. Shaytan, Alexey V. Feofanov, Mikhail P. Kirpichnikov, Olga S. Sokolova, Vasily M. Studitsky
FACT is a histone chaperone that unfolds nucleosomes without ATP hydrolysis. We used electron microscopy to study FACT and FACT:nucleosome complexes, and found that both adopt broad ranges of configurations, indicating high flexibility. We found unex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ef86d14936ba71a071a18917c772af5
https://doi.org/10.1101/2021.07.13.452273
https://doi.org/10.1101/2021.07.13.452273
