Zobrazeno 1 - 10
of 43
pro vyhledávání: '"A. L. Muggleton-HARRIS"'
Autor:
Audrey L. Muggleton-Harris
Publikováno v:
Growth Control During Cell Aging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b4f6e06262e9caea61f1400bfd4dc67
https://doi.org/10.1201/9781003068150-20
https://doi.org/10.1201/9781003068150-20
Publikováno v:
Molecular Human Reproduction. 4:67-70
Biopsied cell samples can remain in storage following an initial, unequivocally successful preimplantation genetic diagnosis (PGD). The fidelity of the DNA template for polymerase chain reaction (PCR) amplification of microtubed human preimplantation
Publikováno v:
Human Reproduction. 11:2230-2238
This study was undertaken to establish baseline data on the chromosomal status of 'failed-fertilized' oocytes derived from in-vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) procedures. A cytogenetic analysis was undertaken on 16
Publikováno v:
Human Reproduction. 10:1021-1029
Human embryos have been biopsied at either the cleavage or the blastocyst stage of development. One to two blastomeres were removed from cleavage-stage embryos and 2-6 cells from blastocysts. The biopsy specimens were subjected to gene amplification
Publikováno v:
Molecular Human Reproduction. 1:101-109
Publikováno v:
Current Opinion in Obstetrics and Gynecology. 5:600-605
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1097:81-85
Cloned cDNAs coding for eye-lens fibre cell-membrane proteins, MIP and MP70, were used to detect restriction fragment length polymorphisms (RFLPs) in genomic DNA from inbred mice with autosomally inherited cataracts. Whereas distinct RFLPs associated
Autor:
I. Findlay, Audrey L. Muggleton-Harris
Publikováno v:
Human Reproduction. 6:85-92
Methods previously used for the biopsy of preimplantation mouse embryos have been applied to individual 'spare' human embryos. Early cleavage-stage human embryos have been cultured and individual blastomeres removed following zonae thinning or drilli
Autor:
Audrey L. Muggleton-Harris, David G. Whittingham, Leroy Hood, Christopher M. Gomez, Carol Readhead
Publikováno v:
Proceedings of the National Academy of Sciences. 87:4481-4484
As a model for the detection of human genetic disease in preimplantation embryos, we describe a method in which trophectoderm biopsy samples from viable mouse blastocysts are simultaneously analyzed for the presence of a normal or mutant allele of th
Publikováno v:
Human Reproduction. 5:217-220
The culture of human preimplantation embryos from the 1-cell to the morula/blastocyst stage of development is not satisfactory at present. The success of various IVF laboratories ranges from 18 to 23%, therefore there is a requirement for improvement