Zobrazeno 1 - 10
of 19
pro vyhledávání: '"A. L. Mikheikin"'
Autor:
A. L. Mikheikin, Jason Reed, Amir A. Toor, Sean Koebley, Alden Chesney, Loren Picco, Daniel Guest, Taha Al Juhaishi, Kevin Leslie, Xiaojie Zhang, Catherine H. Roberts, Wendy McConnell-Wells, Joshua H Lehman
Publikováno v:
ACS Nano. 14:15385-15393
DNA length polymorphisms are found in many serious diseases, and assessment of their length and abundance is often critical for accurate diagnosis. However, measuring their length and frequency in a mostly wild-type background, as occurs in many situ
Autor:
Andrey L. Mikheikin, Sergey A Surzhikov, Olga A. Zasedateleva, Vadim A. Vasiliskov, Sergey V. Pan'kov, Irina V. Grechishnikova, Lev L. Kisselev, Alexander S. Zasedatelev
Publikováno v:
BioTechniques, Vol 44, Iss 1, Pp 77-83 (2008)
To analyze RNA interactions with RNA binding molecules an RNA microchip containing immobilized oligoribonucleotides with protective groups [t-butyldimethylsilyl (tBDMS)] at 2′-O- positions was developed. The oligonucleotides were immobilized within
Externí odkaz:
https://doaj.org/article/7a75dda097d24a06a9dd97bb8002b2fd
Autor:
Wendy McConnell-Wells, Kevin Leslie, Loren Picco, Xiaojie Zhang, Amir A. Toor, Sean Koebley, Alden Chesney, Joshua H Lehman, Daniel Guest, Taha Al Juhaishi, A. L. Mikheikin, Jason Reed, Catherine H. Roberts
Publikováno v:
Blood. 136:21-22
Introduction DNA length polymorphisms are difficult to diagnose due to their repetitive or variable elements. Within the FLT3 gene, internal tandem duplications (ITDs) range from 200 bp in length and are associated with poor prognosis in acute myeloi
Autor:
James K. Gimzewski, Anita Olsen, Andrew Yacoot, Kevin Leslie, Bud Mishra, Amir A. Toor, Oliver D Payton, Jason Reed, A. L. Mikheikin, Alden Chesney, Loren Picco, Freddie Russell-Pavier
Publikováno v:
Nature communications, vol 8, iss 1
Mikheikin, A, Payton, O, Picco, L, Russell-Pavier, F, Yacoot, A, Olsen, A, Leslie, K, Toor, A, Chesney, A, Gimzewski, JK, Mishra, B & Reed, J 2017, ' DNA nanomapping using CRISPR-Cas9 as a programmable nanoparticle ', Nature Communications, vol. 8, pp. 1665-1674 . https://doi.org/10.1038/s41467-017-01891-9
Nature Communications
Mikheikin, A; Olsen, A; Leslie, K; Russell-Pavier, F; Yacoot, A; Picco, L; et al.(2017). DNA nanomapping using CRISPR-Cas9 as a programmable nanoparticle. NATURE COMMUNICATIONS, 8, 1665. doi: 10.1038/s41467-017-01891-9. UCLA: Retrieved from: http://www.escholarship.org/uc/item/0zd9459t
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Mikheikin, A, Payton, O, Picco, L, Russell-Pavier, F, Yacoot, A, Olsen, A, Leslie, K, Toor, A, Chesney, A, Gimzewski, JK, Mishra, B & Reed, J 2017, ' DNA nanomapping using CRISPR-Cas9 as a programmable nanoparticle ', Nature Communications, vol. 8, pp. 1665-1674 . https://doi.org/10.1038/s41467-017-01891-9
Nature Communications
Mikheikin, A; Olsen, A; Leslie, K; Russell-Pavier, F; Yacoot, A; Picco, L; et al.(2017). DNA nanomapping using CRISPR-Cas9 as a programmable nanoparticle. NATURE COMMUNICATIONS, 8, 1665. doi: 10.1038/s41467-017-01891-9. UCLA: Retrieved from: http://www.escholarship.org/uc/item/0zd9459t
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Progress in whole-genome sequencing using short-read (e.g.
Physical mapping of DNA can be used to detect structural variants and for whole-genome haplotype assembly. Here, the authors use CRISPR-Cas9 and high-speed atomic force microscopy to ‘
Physical mapping of DNA can be used to detect structural variants and for whole-genome haplotype assembly. Here, the authors use CRISPR-Cas9 and high-speed atomic force microscopy to ‘
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d223319396faa3d65c15933a0a34107b
https://escholarship.org/uc/item/0zd9459t
https://escholarship.org/uc/item/0zd9459t
Publikováno v:
Methods. 60:161-168
Flexible polymer linkers play an important role in various imaging and probing techniques that require surface immobilization, including atomic force microscopy (AFM). In AFM force spectroscopy, polymer linkers are necessary for the covalent attachme
Autor:
Loren Picco, Anita Olsen, James K. Gimzewski, Oliver D Payton, A. L. Mikheikin, Jason Reed, Bud Mishra
Publikováno v:
Analytical chemistry. 88(5)
Motivated by reports of low-level DNA contamination in popular commercial DNA purification kits, we employed a novel high-speed atomic force microscopy (HS-AFM) method to detect and characterize particulate and polymeric contaminants in four such sys
Publikováno v:
Nucleic Acids Research
DNA polymerases are essential enzymes in all domains of life for both DNA replication and repair. The primary DNA replication polymerase from Sulfolobus solfataricus (SsoDpo1) has been shown previously to provide the necessary polymerization speed an
Autor:
Alexander S. Zasedatelev, Sergey V. Pan'kov, Lev L. Kisselev, Sergey Surzhikov, V. A. Vasiliskov, A. L. Mikheikin, Irina V. Grechishnikova, O. A. Zasedateleva
Publikováno v:
BioTechniques. 44:77-83
To analyze RNA interactions with RNA binding molecules an RNA microchip containing immobilized oligoribonucleotides with protective groups [t-butyldimethylsilyl (tBDMS)] at 2′-O- positions was developed. The oligonucleotides were immobilized within
Autor:
A. S. Krylov, A. D. Mirzabekov, A. Yu. Rubina, S. V. Pan'kov, Alexander V. Chudinov, A. L. Mikheikin, Alexander S. Zasedatelev, A. I. Yaroshchuk
Publikováno v:
Molecular Biology. 37:902-911
To assess the DNA amount in samples (e.g., in biological microchip gel pads) by means of fluorescent dyes, one should use the dyes whose fluorescence weakly depends on DNA composition and structure. With the ImD-310 dye created for this purpose, we h
Publikováno v:
Analytical chemistry, vol 86, iss 13
Analytical Chemistry
Analytical Chemistry
Quantitative polymerase chain reaction is the current "golden standard" for quantification of nucleic acids; however, its utility is constrained by an inability to easily and reliably detect multiple targets in a single reaction. We have successfully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8613ec113ce61afa71b13b18bb208c6b
https://escholarship.org/uc/item/11f997xq
https://escholarship.org/uc/item/11f997xq