Zobrazeno 1 - 10
of 1 481
pro vyhledávání: '"A. L. Mayer"'
Autor:
Guilherme Nader-Marta, Christian Singer, Dominik Hlauschek, Angela DeMichele, Paolo Tarantino, Evandro de Azambuja, Georg Pfeiler, Miguel Martin, Justin M. Balko, Zbigniew Nowecki, Marija Balic, Adam M. Brufsky, Arlene Chan, Patrick G. Morris, Tufia Haddad, Sibylle Loibl, Yuan Liu, Lidija Soelkner, Christian Fesl, Erica L. Mayer, Michael Gnant, on behalf of the PALLAS groups and investigators
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-10 (2024)
Abstract Background Bidirectional crosstalk between HER2 and estrogen receptor (ER) pathways may influence outcomes and the efficacy of endocrine therapy (ET). Low HER2 expression levels (HER2-low) have emerged as a predictive biomarker in patients w
Externí odkaz:
https://doaj.org/article/c4f4965043a847fba7a786c64cdbe554
Autor:
Daniel G. Stover, Roberto Salgado, Oleksander Savenkov, Karla Ballman, Erica L. Mayer, Mark Jesus M. Magbanua, Sherene Loi, Mark Vater, Kristyn Glover, Mark Watson, Yujia Wen, W. Fraser Symmans, Charles Perou, Lisa A. Carey, Ann H. Partridge, Hope S. Rugo
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-5 (2024)
Abstract Association of stromal tumor-infiltrating lymphocytes (sTILs) with survival outcomes among patients with metastatic breast cancer (MBC) remains unclear. The primary objective was to evaluate the association of sTILs with progression-free sur
Externí odkaz:
https://doaj.org/article/83a9a621c06f4389a3a50e11d37a5714
Autor:
Christopher W. J. Lee, Anna Brisland, Xianya Qu, Linda C. Horianopoulos, Guanggan Hu, François L. Mayer, James W. Kronstad
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
The basidiomycete fungus Cryptococcus neoformans is a useful model for investigating mechanisms of fungal pathogenesis in mammalian hosts. This pathogen is the causative agent of cryptococcal meningitis in immunocompromised patients and is in the cri
Externí odkaz:
https://doaj.org/article/6149c8325efd47659c467e649cabba0c
Autor:
Manuel Matzinger, Anna Schmücker, Ramesh Yelagandula, Karel Stejskal, Gabriela Krššáková, Frédéric Berger, Karl Mechtler, Rupert L. Mayer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Comprehensive proteomic analysis is essential to elucidate molecular pathways and protein functions. Despite tremendous progress in proteomics, current studies still suffer from limited proteomic coverage and dynamic range. Here, we utilize
Externí odkaz:
https://doaj.org/article/3af4c2b140ba43258f5b316c468cabdc
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-4 (2023)
The combination of an endocrine agent with a CDK4/6 inhibitor is the standard of care in the first-line setting for patients with hormone receptor-positive, HER2-negative metastatic breast cancer. Randomized trials have demonstrated similar and signi
Externí odkaz:
https://doaj.org/article/0064d50643924f538eaaf8da5ed4adbe
Autor:
Rupert L. Mayer, Rein Verbeke, Caroline Asselman, Ilke Aernout, Adillah Gul, Denzel Eggermont, Katie Boucher, Fabien Thery, Teresa M. Maia, Hans Demol, Ralf Gabriels, Lennart Martens, Christophe Bécavin, Stefaan C. De Smedt, Bart Vandekerckhove, Ine Lentacker, Francis Impens
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Currently, no approved vaccines for Listeria monocytogenes are available. Here, the authors use immunopeptidomics to map bacterial peptides presented on infected cells and identify antigens that, as mRNA vaccine, provide protection in mice.
Externí odkaz:
https://doaj.org/article/97f012cb13b5447e97faef124f7e4dca
Autor:
Rupert L. Mayer, Karl Mechtler
Publikováno v:
Biology, Vol 12, Iss 12, p 1514 (2023)
Immunopeptidomics, as the analysis of antigen peptides being presented to the immune system via major histocompatibility complexes (MHC), is being seen as an imperative tool for identifying epitopes for vaccine development to treat cancer and viral a
Externí odkaz:
https://doaj.org/article/00be61391eb0489aab30a0fd757444ba
Autor:
Cassandra B. Higgins, Allyson L. Mayer, Yiming Zhang, Michael Franczyk, Samuel Ballentine, Jun Yoshino, Brian J. DeBosch
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
NAD + metabolism is potential target to treat metabolic disorders, in part due to the effects of the NAD + dependent enzyme Sirt1. Here the authors report that hepatic nicotinamide phosphoribosyltransferase, a rate-limiting step in the NAD + salvage
Externí odkaz:
https://doaj.org/article/a90017de3aab45c5bda37c839a089c2e
Autor:
Richard M. Walsh, Megan L. Mayer, Christopher H. Sun, Shaun Rawson, Remya Nair, Sarah M. Sterling, Zongli Li
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The Harvard Cryo-Electron Microscopy Center for Structural Biology, which was formed as a consortium between Harvard Medical School, Boston Children’s Hospital, Dana-Farber Cancer Institute, and Massachusetts General Hospital, serves both academic
Externí odkaz:
https://doaj.org/article/d9a2330689554521b1c605072c89289c
Autor:
Francisco Tomás Zapata-Guerrero, Jannett Ayup, Elizabeth L. Mayer-Granados, Jorge Charles-Coll
Publikováno v:
RAUSP Management Journal, Vol 55, Iss 4, Pp 511-530 (2020)
Purpose – The purpose of this paper is to contribute to the knowledge on the efficiency of the incubators in Mexico, from a double-managerial approach (incubator and start-ups) measuring the efficiency oriented to the survival growth in the employm
Externí odkaz:
https://doaj.org/article/4bc03b5b725a45fab30f9e41eff1fd96