Výsledky vyhledávání - "A. L. Márquez"

Akademický článek

Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure

Autor: KM Rifat Faysal, James C Walsh, Nadine Renner, Chantal L Márquez, Vaibhav B Shah, Andrew J Tuckwell, Michelle P Christie, Michael W Parker, Stuart G Turville, Greg J Towers, Leo C James, David A Jacques, Till Böcking

Publikováno v: eLife, Vol 13 (2024)

The HIV-1 capsid has emerged as a tractable target for antiretroviral therapy. Lenacapavir, developed by Gilead Sciences, is the first capsid-targeting drug approved for medical use. Here, we investigate the effect of lenacapavir on HIV capsid stabil

Externí odkaz: https://doaj.org/article/08ba42401fe84baebde255dedc84b832

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Akademický článek

Evaluation of Antibiotic Biodegradation by a Versatile and Highly Active Recombinant Laccase from the Thermoalkaliphilic Bacterium Bacillus sp. FNT

Autor: Jorge Sánchez-SanMartín, Sebastián L. Márquez, Giannina Espina, Rodrigo Cortés-Antiquera, Junsong Sun, Jenny M. Blamey

Publikováno v: Biomolecules, Vol 14, Iss 3, p 369 (2024)

Laccases are industrially relevant enzymes that have gained great biotechnological importance. To date, most are of fungal and mesophilic origin; however, enzymes from extremophiles possess an even greater potential to withstand industrial conditions

Externí odkaz: https://doaj.org/article/166ac5cb4b404236a6397f9989e40c09

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Akademický článek

A comparison of Covid-19 early detection between convolutional neural networks and radiologists

Autor: Alberto Albiol, Francisco Albiol, Roberto Paredes, Juana María Plasencia-Martínez, Ana Blanco Barrio, José M. García Santos, Salvador Tortajada, Victoria M. González Montaño, Clara E. Rodríguez Godoy, Saray Fernández Gómez, Elena Oliver-Garcia, María de la Iglesia Vayá, Francisca L. Márquez Pérez, Juan I. Rayo Madrid

Publikováno v: Insights into Imaging, Vol 13, Iss 1, Pp 1-12 (2022)

Abstract Background The role of chest radiography in COVID-19 disease has changed since the beginning of the pandemic from a diagnostic tool when microbiological resources were scarce to a different one focused on detecting and monitoring COVID-19 lu

Externí odkaz: https://doaj.org/article/30d5c46b7ccb4d4a90085b9f67268cb7

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Akademický článek

Isolation and Identification of Bacteria from Three Geothermal Sites of the Atacama Desert and Their Plant-Beneficial Characteristics

Autor: Patricio Muñoz-Torres, Sebastián L. Márquez, Germán Sepúlveda-Chavera, Steffany Cárdenas-Ninasivincha, Mabel Arismendi-Macuer, Wilson Huanca-Mamani, Yola Aguilar, Antonio Quezada, Franco Bugueño

Publikováno v: Microorganisms, Vol 11, Iss 11, p 2635 (2023)

The Region of Arica and Parinacota (Atacama Desert) offers several unexplored remote sites with unique characteristics that would allow for the formulation of new bioproducts for agriculture. Among them, Jurasi Hot Springs, Polloquere Hot Springs, an

Externí odkaz: https://doaj.org/article/f451f4bef4af4ea19b01a5cfba609571

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Akademický článek

Presenilin mutations and their impact on neuronal differentiation in Alzheimer’s disease

Autor: Mercedes A Hernandez-Sapiens, Edwin E Reza-Zaldívar, Ana L Márquez-Aguirre, Ulises Gómez-Pinedo, Jorge Matias-Guiu, Ricardo R Cevallos, Juan C Mateos-Díaz, Víctor J Sánchez-González, Alejandro A Canales-Aguirre

Publikováno v: Neural Regeneration Research, Vol 17, Iss 1, Pp 31-37 (2022)

The presenilin genes (PSEN1 and PSEN2) are mainly responsible for causing early-onset familial Alzheimer’s disease, harboring ~300 causative mutations, and representing ~90% of all mutations associated with a very aggressive disease form. Presenili

Externí odkaz: https://doaj.org/article/66a250d50ba443c4bb6eeff003fa364d

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