Zobrazeno 1 - 9
of 9
pro vyhledávání: '"A. L. Khandoga"'
Autor:
Anna L. Khandoga, Sandra M Penz, Richard Brandl, Wolfgang Siess, Takayuki Maruyama, Suman Dwivedi, Lisa J. Schober
Publikováno v:
Journal of Thrombosis and Thrombolysis. 32:158-166
Atherosclerosis has an important inflammatory component. Macrophages accumulating in atherosclerotic arteries produce prostaglandin E(2) (PGE(2)), a main inflammatory mediator. Platelets express inhibitory receptors (EP(2), EP(4)) and a stimulatory r
Publikováno v:
Cardiovascular Research. 90:157-164
Aims Oxidative processes and vascular inflammation underlying atherosclerosis lead to an accumulation of lysophosphatidic acid (LPA) molecules in the atheromatous intima. LPA, a platelet-activating component of human atherosclerotic plaques, possibly
Autor:
A. L. Khandoga, Y. Fujiwara, P. Goyal, D. Pandey, R. Tsukahara, A. Bolen, H. Guo, N. Wilke, J. Liu, W. J. Valentine, G. G. Durgam, D. D. Miller, G. Jiang, G. D. Prestwich, G. Tigyi, W. Siess
Publikováno v:
Platelets. 19:415-427
Lysophosphatidic acid (LPA), a component of mildly-oxidized LDL and the lipid rich core of atherosclerotic plaques, elicits platelet activation. LPA is the ligand of G protein-coupled receptors (GPCR) of the EDG family (LPA(1-3)) and the newly identi
Publikováno v:
Thrombosis and Haemostasis. 104:1272-1274
Publikováno v:
Platelets. 25(6)
Publikováno v:
Platelets. 25(3)
Platelets play a central role in atherosclerosis and atherothrombosis, and circulating endocannabinoids might modulate platelet function. Previous studies concerning effects of anandamide (N-arachidonylethanolamide) and 2-arachidonoylglycerol (2-AG)
Publikováno v:
Cardiovascular Research
Aims Oxidative processes and vascular inflammation underlying atherosclerosis lead to an accumulation of lysophosphatidic acid (LPA) molecules in the atheromatous intima. LPA, a platelet-activating component of human atherosclerotic plaques, possibly
Autor:
Gabor Tigyi, Anna L. Khandoga, Jesica R. Williams, James I. Fells, Yuko Fujiwara, Pankaj Goyal, Abby L. Parrill, Donna H. Perygin, Wolfgang Siess
Lysophosphatidic acid (LPA) is a ligand for LPA(1-3) of the endothelial differentiation gene family G-protein-coupled receptors, and LPA(4-8) is related to the purinergic family G-protein-coupled receptor. Because the structure-activity relationship
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b937eeb80836962f10378b9e9ffb2306
https://europepmc.org/articles/PMC2719366/
https://europepmc.org/articles/PMC2719366/
Publikováno v:
Thrombosis and Haemostasis. 103:1268-1269
The EP3-agonist sulprostone, but not prostaglandin E2 potentiates platelet aggregation in human blood