Zobrazeno 1 - 10
of 329
pro vyhledávání: '"A. L. Karr"'
Single cell transcriptomes and multiscale networks from persons with and without Alzheimer’s disease
Autor:
Qi Wang, Jerry Antone, Eric Alsop, Rebecca Reiman, Cory Funk, Jaroslav Bendl, Joel T. Dudley, Winnie S. Liang, Timothy L. Karr, Panos Roussos, David A. Bennett, Philip L. De Jager, Geidy E. Serrano, Thomas G. Beach, Kendall Van Keuren-Jensen, Diego Mastroeni, Eric M. Reiman, Benjamin P. Readhead
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The emergence of single nucleus RNA sequencing (snRNA-seq) offers to revolutionize the study of Alzheimer’s disease (AD). Integration with complementary multiomics data such as genetics, proteomics and clinical data provides powerful oppor
Externí odkaz:
https://doaj.org/article/583e7a46c0434985a97259a70db5d4e3
Autor:
Liqiang Zhang, Yize Henry Li, Karen Kibler, Simona Kraberger, Arvind Varsani, Julie Turk, Nora Elmadbouly, Emily Aliskevich, Laurel Spaccarelli, Bereket Estifanos, Junior Enow, Isabela Rivabem Zanetti, Nicholas Saldevar, Efrem Lim, Jessika Schlievert, Kyle Browder, Anjali Wilson, Fernando Arcos Juan, Aubrey Pinteric, Aman Garg, Henna Monder, Rohan Saju, Savanah Gisriel, Bertram Jacobs, Timothy L Karr, Esther Borges Florsheim, Vivek Kumar, John Wallen, Masmudur Rahman, Grant McFadden, Brenda G Hogue, Alexandra R Lucas
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 9, Pp 1-19 (2023)
Abstract SARS‐CoV‐2 acute respiratory distress syndrome (ARDS) induces uncontrolled lung inflammation and coagulopathy with high mortality. Anti‐viral drugs and monoclonal antibodies reduce early COVID‐19 severity, but treatments for late‐s
Externí odkaz:
https://doaj.org/article/173774a4d3874632894de3a50c2ec7e5
Autor:
Collin Jugler, Francisca J. Grill, Lukas Eidenberger, Timothy L. Karr, Thomas E. Grys, Herta Steinkellner, Douglas F. Lake, Qiang Chen
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Monoclonal antibodies (mAbs) are important proteins used in many life science applications, from diagnostics to therapeutics. High demand for mAbs for different applications urges the development of rapid and reliable recombinant production platforms
Externí odkaz:
https://doaj.org/article/46565346851f4720ba84712d273da126
Autor:
Balasubramanian Cibichakravarthy, Juan A. Oses-Prieto, Michael Ben-Yosef, Alma L. Burlingame, Timothy L. Karr, Yuval Gottlieb
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT Maternally transmitted obligatory endosymbionts are found in the female gonads as well as in somatic tissue and are expected to provide missing metabolite to their hosts. These deficiencies are presumably complemented through specific symbio
Externí odkaz:
https://doaj.org/article/1e91bba5e43b4b9eb8cda9fbcd3ecc45
Autor:
Kimihide Ibaraki, Mihoko Nakatsuka, Takashi Ohsako, Masahide Watanabe, Yu Miyazaki, Machi Shirakami, Timothy L Karr, Rikako Sanuki, Masatoshi Tomaru, Toshiyuki Takano-Shimizu-Kouno
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 8 (2021)
AbstractMale reproduction encompasses many essential cellular processes and interactions. As a focal point for these events, sperm offer opportunities for advancing our understanding of sexual reproduction at multiple levels during development. Using
Externí odkaz:
https://doaj.org/article/802b168fce0d494bb3ea1a0a96c8543d
Autor:
Michihiro Takami, Hans Moritz Günther, P. Christian Schneider, Tracy L. Beck, Jennifer L. Karr, Youichi Ohyama, Roberto Galván-Madrid, Taichi Uyama, Marc White, Konstantin Grankin, Deirdre Coffey, Chun-Fan Liu, Misato Fukagawa, Nadine Manset, Wen-Ping Chen, Tae-Soo Pyo, Hsien Shang, Thomas P. Ray, Masaaki Otsuka, Mei-Yin Chou
Publikováno v:
The Astrophysical Journal Supplement Series, Vol 264, Iss 1, p 1 (2022)
We present Gemini-NIFS, Very Large Telescope-SINFONI, and Keck-OSIRIS observations of near-IR [Fe ii ] emission that are associated with well-studied jets from three active T Tauri stars—RW Aur A, RY Tau, and DG Tau—taken from 2012 to 2021. We pr
Externí odkaz:
https://doaj.org/article/87be1dd005bb4eb3bc69f4b8243d7a00
Autor:
Emma Whittington, Desiree Forsythe, Kirill Borziak, Timothy L. Karr, James R. Walters, Steve Dorus
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background Rapid evolution is a hallmark of reproductive genetic systems and arises through the combined processes of sequence divergence, gene gain and loss, and changes in gene and protein expression. While studies aiming to disentangle th
Externí odkaz:
https://doaj.org/article/253a9d2e3f6649efb9a537b55bdb2c76
Autor:
Grant McFadden, Timothy L Karr, Juliane Daggett-Vondras, Jacquelyn Kilbourne, Kenneth Lowe, Anne Everts, Mackenzie Cashen, Ami D. Gutierrez-Jensen, Maksuda Hossain, Junior A. Enow, Fleur van Oosterom, Masmudur M. Rahman
Oncolytic viruses exploited for cancer therapy have been developed to selectively infect, replicate, and kill cancer cells to inhibit tumor growth. However, in some cancer cells, oncolytic viruses are often limited in completing their full replicatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb929c5be05701bf119a4d98e60c0f4
https://doi.org/10.1158/2767-9764.c.6649208
https://doi.org/10.1158/2767-9764.c.6649208
Autor:
Grant McFadden, Timothy L Karr, Juliane Daggett-Vondras, Jacquelyn Kilbourne, Kenneth Lowe, Anne Everts, Mackenzie Cashen, Ami D. Gutierrez-Jensen, Maksuda Hossain, Junior A. Enow, Fleur van Oosterom, Masmudur M. Rahman
Tumor burden of individual mouse received Colo205 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2458d33c9cde8d7c197c1f4a95d9c81a
https://doi.org/10.1158/2767-9764.22843706.v1
https://doi.org/10.1158/2767-9764.22843706.v1
Autor:
Grant McFadden, Timothy L Karr, Juliane Daggett-Vondras, Jacquelyn Kilbourne, Kenneth Lowe, Anne Everts, Mackenzie Cashen, Ami D. Gutierrez-Jensen, Maksuda Hossain, Junior A. Enow, Fleur van Oosterom, Masmudur M. Rahman
List of proteins identified using mass spectrometry, and their relative abundances in the nuclear and cytosolic fractions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebd5491d462c232730ce4b2c235602a
https://doi.org/10.1158/2767-9764.22843694
https://doi.org/10.1158/2767-9764.22843694