Zobrazeno 1 - 10
of 1 201
pro vyhledávání: '"A. L. Haines"'
Autor:
Tong Tong, Congcong Zhu, John J. Farrell, Zainab Khurshid, Alzheimer’s Disease Sequencing Project, Alzheimer’s Disease Neuroimaging Initiative, Eden R. Martin, Margaret A. Pericak-Vance, Li-San Wang, William S. Bush, Gerard D. Schellenberg, Jonathan L. Haines, Wei Qiao Qiu, Kathryn L. Lunetta, Lindsay A. Farrer, Xiaoling Zhang
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Background Blood-derived mitochondrial DNA copy number (mtDNA-CN) is a proxy measurement of mitochondrial function in the peripheral and central systems. Abnormal mtDNA-CN not only indicates impaired mtDNA replication and transcription machi
Externí odkaz:
https://doaj.org/article/6359a6836b184b369a74d2bbfb50ce84
Autor:
Jeroen Molinger, John Whittle, Henrik Endeman, David MacLeod, Rajan Gupta, Marat Fudim, Krista L. Haines, Christina Barkauskas, Zachary Healy, Paul Wischmeyer, Jan Bakker
Publikováno v:
Frontiers in Anesthesiology, Vol 3 (2024)
BackgroundMuscle wasting is a common finding in critically ill patients associated with increased days of mechanical ventilation in the ICU. Muscle wasting and associated morphological changes are hallmarks of ICU-acquired weakness. Muscle wasting ca
Externí odkaz:
https://doaj.org/article/07396a54023c4250bf13e957a840efce
Autor:
Jeroen Molinger, John Whittle, Susie Cha, David MacLeod, Marat Fudim, Luis Ulloa, Christina Barkauskas, Zachary Healy, Krista L. Haines, Rajan T. Gupta, Henrik Endeman, Mathieu van der Jagt, Diederik Gommers, Jan Bakker, Paul E. Wischmeyer
Publikováno v:
Frontiers in Anesthesiology, Vol 3 (2024)
IntroductionThe COVID-19 pandemic brought unprecedented challenges to healthcare systems worldwide, particularly the often challenging physical recovery from critical illness. Among the myriad complications faced by these patients, ICU-acquired weakn
Externí odkaz:
https://doaj.org/article/c1678bfd796f45509c3428e33d0f7e17
Autor:
Holly N. Cukier, Shaina A. Simon, Eugene Tang, Charles G. Golightly, Mayra Juliana Laverde-Paz, Larry Deon Adams, Takiyah D. Starks, Jeffery M. Vance, Michael L. Cuccaro, Jonathan L. Haines, Goldie S. Byrd, Margaret A. Pericak-Vance, Derek M. Dykxhoorn
Publikováno v:
Stem Cell Research, Vol 76, Iss , Pp 103364- (2024)
The ATP-binding cassette, subfamily A (ABC1), member 7 (ABCA7) gene is associated with Alzheimer’s disease (AD) risk in populations of African, Asian, and European ancestry1-5. Numerous ABCA7 mutations contributing to risk have been identified, inc
Externí odkaz:
https://doaj.org/article/a261ce83f35c4a99bceebaac13a6fffe
Publikováno v:
Atmospheric Measurement Techniques, Vol 16, Pp 3515-3529 (2023)
Organic sulfur and sulfate compounds, which are tracers for sources and atmospheric processes, are not currently measured in national monitoring networks such as the Interagency Monitoring of Protected Visual Environments (IMPROVE). The goal of this
Externí odkaz:
https://doaj.org/article/440adf1a84804a98bf2033b6a243ef38
Autor:
Moonil Kang, Ting Fang Alvin Ang, Sherral A. Devine, Richard Sherva, Shubhabrata Mukherjee, Emily H. Trittschuh, Laura E. Gibbons, Phoebe Scollard, Michael Lee, Seo-Eun Choi, Brandon Klinedinst, Connie Nakano, Logan C. Dumitrescu, Alaina Durant, Timothy J. Hohman, Michael L. Cuccaro, Andrew J. Saykin, Walter A. Kukull, David A. Bennett, Li-San Wang, Richard P. Mayeux, Jonathan L. Haines, Margaret A. Pericak-Vance, Gerard D. Schellenberg, Paul K. Crane, Rhoda Au, Kathryn L. Lunetta, Jesse B. Mez, Lindsay A. Farrer
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-22 (2023)
Abstract Background More than 75 common variant loci account for only a portion of the heritability for Alzheimer’s disease (AD). A more complete understanding of the genetic basis of AD can be deduced by exploring associations with AD-related endo
Externí odkaz:
https://doaj.org/article/fe39bfd5b90d4d70a686b48ed5244454
Autor:
Elliott R Haut, Edward Harvey, George Kasotakis, Brian K Yorkgitis, Hassan Mir, Patrick B Murphy, Anna Miller, Jennifer J Freeman, Krista L Haines, Eric Hasenboehler, Thomas Higgins, Joseph Hoegler, Sarah Cantrell, William T Obremskey, Meghan Wally, Basem Attum, Rachel Seymour, Nimitt Patel, William Ricci, Brandy B Padilla-Jones
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 8, Iss 1 (2023)
Objectives Fracture is a common injury after a traumatic event. The efficacy and safety of non-steroidal anti-inflammatory drugs (NSAIDs) to treat acute pain related to fractures is not well established.Methods Clinically relevant questions were dete
Externí odkaz:
https://doaj.org/article/c3c9ae33305b4694b3c5010aa7ed5c16
Autor:
Min Qiao, Annie J. Lee, Dolly Reyes‐Dumeyer, Giuseppe Tosto, Kelley Faber, Alison Goate, Alan Renton, Michael Chao, Brad Boeve, Carlos Cruchaga, Margaret Pericak‐Vance, Jonathan L. Haines, Roger Rosenberg, Debby Tsuang, Robert A. Sweet, David A. Bennett, Robert S. Wilson, Tatiana Foroud, Richard Mayeux, Badri N. Vardarajan
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 5, Pp 744-756 (2023)
Abstract Objective To compute penetrance and recurrence risk using a genome‐wide PRS (including and excluding the APOE region) in families with Alzheimer's disease. Methods Genotypes from the National Institute on Aging Late‐Onset Alzheimer's Dis
Externí odkaz:
https://doaj.org/article/ca34451dd2fe4c19b1a16a4280fe7a72
Autor:
Krista L. Haines, Tetsu Ohnuma, Charles Trujillo, Obanor Osamudiamen, Vijay Krishnamoorthy, Karthik Raghunathan, Paul E. Wischmeyer
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-9 (2022)
Abstract Introduction Early data suggest use of a mixed lipid emulsion (LE) with a soybean oil reduction strategy in parenteral nutrition (PN) may improve clinical outcomes. Duke University Hospital made a full switch to a Soybean oil/MCT/Olive/Fish
Externí odkaz:
https://doaj.org/article/9560702334284c1ea5a0909352bfb941
Autor:
Hee Soo Jung, Rishi Rattan, Anna Goldenberg, Erin Chang, Stephanie Bonne, D'Andrea Joseph, Amanda L Teichman, Patrick B Murphy, Courtney Edwards, Christina Colosimo, Anna Liveris, Emily Lawson, Kathleen Fox, Jennifer J Freeman, Krista L Haines, Linda Dultz, Farheen A Qurashi, Nathan Polite, Rachel L Choron, Sandra Arabian, Andrew T Schramm, Hassan Naser A Mashbari, Randi N Smith
Publikováno v:
Trauma Surgery & Acute Care Open, Vol 8, Iss 1 (2023)
Background Intimate partner violence (IPV) is a serious public health issue with a substantial burden on society. Screening and intervention practices vary widely and there are no standard guidelines. Our objective was to review research on current p
Externí odkaz:
https://doaj.org/article/b576a1b7aede4daa99f73b0fae0448a1