Zobrazeno 1 - 10
of 628
pro vyhledávání: '"A. L. Dent"'
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
IntroductionObesity during childhood is a serious and growing chronic disease with consequences for lifelong health. In an effort to advance research into the preclinical indicators of pediatric obesity, we examined longitudinal assessments of uric a
Externí odkaz:
https://doaj.org/article/0d93d44c5fff429da5ecf3e47699668d
Autor:
D. Alejandro Canaria, Maia G. Clare, Bingyu Yan, Charlotte B. Campbell, Zachariah A. Ismaio, Nicole L. Anderson, Sungtae Park, Alexander L. Dent, Majid Kazemian, Matthew R. Olson
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IL-9-producing CD4+ T helper cells, termed Th9 cells, differentiate from naïve precursor cells in response to a combination of cytokine and cell surface receptor signals that are elevated in inflamed tissues. After differentiation, Th9 cells accumul
Externí odkaz:
https://doaj.org/article/f8a357bbff2a4fd8819701a96855a258
Autor:
Mustafa Tamim Alam Khan, Ronit Patnaik, Allison N. Laffoon, Lucijana Krokar, Spencer R. Ince, Estefania Hurtado, Mio Kitano, Danielle M. Fritze, Daniel L. Dent
Publikováno v:
Journal of Surgical Research. 288:43-50
Autor:
Yuhong Chen, Mei Yu, Yongwei Zheng, Guoping Fu, Gang Xin, Wen Zhu, Lan Luo, Robert Burns, Quan-Zhen Li, Alexander L. Dent, Nan Zhu, Weiguo Cui, Laurent Malherbe, Renren Wen, Demin Wang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
B cell response and antibody production are generally facilitated by CD4+ follicular helper (Tfh) cells. Here the authors identify a subset of CXCR5+PD1+CD8+ Tfh cells that is normally suppressed by STAT5 signaling, so that STAT5 deficiency in mice i
Externí odkaz:
https://doaj.org/article/3b58b83ee76b4ab8925812d290639692
Publikováno v:
IEEE Transactions on Smart Grid. 14:878-888
Publikováno v:
The Journal of Immunology. 210:905-915
High-affinity allergen-specific IgE is essential for the severe allergic anaphylaxis response. High-affinity Abs are formed by successive rounds of selection of Ag-specific B cells in the germinal center (GC); however, several studies have shown that
Autor:
Rachael Keating, Jenny L. Johnson, David C. Brice, Jocelyn G. Labombarde, Alexander L. Dent, Maureen A. McGargill
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT Enhancing the generation of broadly reactive antibodies against influenza A virus (IAV) is a pertinent goal toward developing a universal IAV vaccine. While antibodies that bind conserved IAV epitopes have been identified in humans, antibodi
Externí odkaz:
https://doaj.org/article/5b32c45fd4eb4b00b07f17f7bdc5be4e
Autor:
Hannah R. Turbeville, Ashley C. Johnson, Michael R. Garrett, Elena L. Dent, Jennifer M. Sasser
Publikováno v:
Physiological Reports, Vol 8, Iss 13, Pp n/a-n/a (2020)
Abstract The burden of hypertension in the United States is increasing and yields significant morbidity and mortality, and sex differences in hypertension are widely recognized. Reduced nitric oxide (NO) bioavailability and increased oxidative stress
Externí odkaz:
https://doaj.org/article/87a111f2f97243ecbea15ea67be2a820
Autor:
Victor H. Carpio, Florentin Aussenac, Lucinda Puebla-Clark, Kyle D. Wilson, Alejandro V. Villarino, Alexander L. Dent, Robin Stephens
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101310- (2020)
Summary: Hybrid Th1/Tfh cells (IFN-γ+IL-21+CXCR5+) predominate in response to several persistent infections. In Plasmodium chabaudi infection, IFN-γ+ T cells control parasitemia, whereas antibody and IL-21+Bcl6+ T cells effect final clearance, sugg
Externí odkaz:
https://doaj.org/article/b487e74dccc04a409f18f5c68412ec2a
Publikováno v:
Physiological Reports, Vol 8, Iss 13, Pp n/a-n/a (2020)
Abstract Systemic lupus erythematosus (SLE) is an autoimmune disorder with prevalent hypertension and renal disease. To avoid side effects of immunosuppressive drugs, alternative therapies are needed. Curcumin has been used in Eastern medicine for it
Externí odkaz:
https://doaj.org/article/c7322fac4d4f45ac9e4abc7ea0aa5edf