Shaping Modern Vaccines: Adjuvant Systems Using MicroCrystalline Tyrosine (MCT®)

Autor: Matthew D. Heath, Mona O. Mohsen, Pieter-Jan de Kam, Thalia L. Carreno Velazquez, Simon J. Hewings, Matthias F. Kramer, Thomas M. Kündig, Martin F. Bachmann, Murray A. Skinner

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

The concept of adjuvants or adjuvant systems, used in vaccines, exploit evolutionary relationships associated with how the immune system may initially respond to a foreign antigen or pathogen, thus mimicking natural exposure. This is particularly rel

Externí odkaz: https://doaj.org/article/b848cfa9b4bd4e09a7bf354cae148917

The next generation virus‐like particle platform for the treatment of peanut allergy

Autor: Jan M. Sobczak, Pascal S. Krenger, Federico Storni, Mona O. Mohsen, Ina Balke, Gunta Reseviča, Matthew D. Heath, Thalia L. Carreno Velazquez, Matthias F. Kramer, Callum J. W. Scott, Murray A. Skinner, Andris Zeltiņš, Thomas M. Kündig, Monique Vogel, Martin F. Bachmann

Publikováno v: Allergy.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::85ff50868e0216e24df47548617b3419
https://doi.org/10.1111/all.15704

Venom Immunotherapy: From Proteins to Product to Patient Protection

Autor: Johannes Grosch, Matthew D. Heath, Peter Schmid-Grendelmeier, Simon J Hewings, David B K Golden, Ludger Klimek, Simon Blank, Thilo Jakob, Murray A. Skinner, Thalia L Carreno Velazquez, Martin Feindor, Matthias F. Kramer

Publikováno v: Toxins, Vol 13, Iss 616, p 616 (2021)
Toxins
Toxins 13:616 (2021)

In this review, we outline and reflect on the important differences between allergen-specific immunotherapy for inhalant allergies (i.e., aeroallergens) and venom-specific immunotherapy (VIT), with a special focus on Venomil® Bee and Wasp. Venomil®

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22396ab4a4adc7823970bdcee630613d
https://www.mdpi.com/2072-6651/13/9/616

Biochronology, paleoenvironments, and stratigraphic sequences of the late Albian–middle Eocene fore-arc Vizcaino basin, western Baja California, Mexico

Autor: Adriana Miranda, A. L. Carreno, Arturo Martín-Barajas, Maritza Canache, Javier Helenes, Iraida Paredes, Juan Gabriel Flores-Trujillo

Publikováno v: AAPG Bulletin. 103:1045-1069

The Vizcaino fore-arc basin accumulated approximately 4 km (∼13,000 ft) of upper Albian–middle Eocene siliciclastic marine sedimentary rocks derived from the Peninsular Ranges in Baja California. Data from eight exploratory wells document the mic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ed6b6c79e0ff188ed50174ffd0c0fd43
https://doi.org/10.1306/10021817349

Efficacy and Safety of Epratuzumab in Moderately to Severely Active Systemic Lupus Erythematosus: Results From Two Phase III Randomized, Double-Blind, Placebo-Controlled Trials

Autor: Clowse, Megan E. B, Wallace, Daniel J., Furie, Richard A., Petri, Michelle A., Pike, Marilyn C., Leszczyński, Piotr, Neuwelt, C. Michael, Hobbs, Kathryn, Keiserman, Mauro, Duca, Liliana, Kalunian, Kenneth C., Galateanu, Catrinel, Bongardt, Sabine, Stach, Christian, Beaudot, Carolyn, Kilgallen, Brian, Gordon, Caroline, Batalov, A., Bojinca, M., Djerassi, R., Duca, L., Horak, P., Kolarov, Z., Milasiene, R., Monova, D., Otsa, K., Pileckyte, M., Popova, T., Radulescu, F., Rashkov, R., Rednic, S., Repin, M., Stoilov, R., Tegzova, D., Vezikova, N., Vitek, P., Zainea, C., East, Far, Baek, H., Chen, Y., Chiu, Y., Cho, C., Chou, C., Choe, J., Huang, C., Kang, Y., Kang, S., Lai, N., Lee, S., Park, W., Shim, S., Suh, C., Yoo, W., Armengol, H. Avila, Zapata, F. Avila, Santiago, M. Barreto, Cavalcanti, F., Chahade, W., Costallat, L., Keiserman, M., Alcala, J. Orozco, Remus, C. Ramos, Roimicher, L., Abu Shakra, M., Agarwal, V., Agmon Levin, N., Kadel, J., Levy, Y., Mevorach, D., Paran, D., Reitblat, T., Rosner, I., Shobha, V., Sthoeger, Z., Zisman, D., Ayesu, K., Berney, S., Box, J., Busch, H., Buyon, J., Carter, J., Chi, J., Clowse, M., Collins, R., Dao, K., Diab, I., Dikranian, A., El Shahawy, M., Gaylis, N., Grossman, J., Halpert, E., Huff, J., Jarjour, W., Kao, A., Katz, R., Kennedy, A., Khan, M., Kivitz, A., Kohen, M., Lawrence Ford, T., Lawson, J., Levesque, M., Lowenstein, M., Majjhoo, A., Mcarthur, R., Mclain, D., Merrill, J., Murillo, A., Neucks, S., Niemer, G., Noaiseh, G., Parker, C., Pantojas, C., Pattanaik, D., Petri, M., Pickrell, P., Reveille, J., Roman Miranda, A., Rothfield, N., Sankoorikal, A., Sayers, M., Singhal, A., Snyder, A., Striebich, C., Vo, Q., von Feldt, J., Wallace, D., Wasko, M., Young, C., Adelstein, S., Hall, S., Littlejohn, G., Nicholls, D., Suranyi, M., Amoura, Z., Bannert, B., Behrens, F., Perez, L. Carreno, Chakravarty, K., Gonzales, F. Diaz, Davies, K., Doria, Andrea, Emery, P., Fernández Nebro, A., Govoni, M., Hachulla, E., Hellmich, B., Houssiau, F., Malaise, M., Margaux, J., Maugars, Y., Muñoz Fernández, S., Navarro, F., Ordi Ros, J., Pellerito, R., Pena Sagredo, J., Roussou, E., Schmidt, R. E., Ucar Angulo, E., Viallard, J. F., Westhovens, R., Worm, M., Yee, C. S., Nayiager, S., Reuter, H., Spargo, C., Bazela, B., Brzosko, M., Chudzik, D., Gasztonyi, B., Geher, P., Ionescu, R., Jeka, S., Kemeny, L., Kiss, E., Kotyla, P., Kovacs, L., Kovalenko, V., Kucharz, E., Kwiatkowska, B., Leszczynski, P., Levchenko, E., Lysenko, G., Majdan, M., Mihailov, C., Nalotov, S., Nedelciu, M., Pavel, M., Raskina, T., Rebrov, B., Rezus, E., Semen, T., Smakotina, S., Stanislavchuk, M., Stanislav, M., Szombati, I., Szucs, G., Udrea, G., Zajdel, J., Zon Giebel, A., Bonfiglioli, R., Bustamante, R., Klumb, E., Ramirez, G. Medrano, Neiva, C., Olguin, M., Gonzaga, J. Reyes, Scotton, A., Ayala, S. Sicsik, Ximenes, A., Sharma, R., Srikantiah, C., Aelion, J., Aranow, C., Baker, M., Chadha, A., Chao, J., Chatham, W., Chow, A., Clay, C., Cohen Gadol, S., Conaway, D., Denburg, J., Escalante, A., Espinoza, L., Fiechtner, J., Fortin, I., Fraser, A., Furie, R., Gladman, D., Goddard, D., Goldberg, M., Gonzalez Rivera, R., Gorman, J., Griffin, R., Haaland, D., Halter, D., Hemaiden, A., Hobbs, K., Joshi, V., Lim, S., Kalunian, K., Karpouzas, G., Khraishi, M., Lafyatis, R., Lidman, R., Lue, C., Mohan, M., Mease, P., Mehta, C., Mizutani, W., Nami, A., Nascimento, J., Neuwelt, C., Pappas, J., Pope, J., Porges, A., Roane, G., Rosenberg, D., Ross, S., Saadeh, C., Scoville, C., Sherrer, Y., Solomon, M., Surbeck, W., Valenzuela, G., Waller, P., Alten, R., Baerwald, C., Bienvenu, B., Bombardieri, S., Braun, J., Dival, L., Espinosa, G., Fernandez, I. Figueroa, Gomez Reino, J., Gordon, C., Hiepe, F., Hopkinson, N., Isenberg, D., Jacobi, A., Jorgensen, C., Guern, V. Le, Paul, C., Pego Reigosa, J. M., Heredia, J. Rodriguez, Rubbert Roth, A., Sabbadini, M., Schroeder, J., Schwarting, A., Spieler, W., Valesini, G., Wollenhaupt, J., Mendoza, A. Zea, Zouboulis, C.

Publikováno v: Arthritis & Rheumatology (Hoboken, N.j.)

Objective Epratuzumab, a monoclonal antibody that targets CD22, modulates B cell signaling without substantial reductions in the number of B cells. The aim of this study was to report the results of 2 phase III multicenter randomized, double‐blind,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f2cf21ab295304e86558058503bbae0f
http://hdl.handle.net/11573/1152010