Zobrazeno 1 - 10
of 3 015
pro vyhledávání: '"A. L Ford"'
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-8 (2024)
Abstract Many state-of-the-art climate models are unable to reproduce the observed 20th century surface warming pattern in the tropical Pacific Ocean, casting doubt on the robustness of future projections. Here, we examine past changes in the tropica
Externí odkaz:
https://doaj.org/article/9fcab6ea765a42b48664d33e933e887a
Autor:
Blanca De Dios Perez, Vicky Booth, Roshan das Nair, Nikos Evangelou, Juliet Hassard, Helen L. Ford, Ian Newsome, Kate Radford
Publikováno v:
BMC Health Services Research, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background To explore how a vocational rehabilitation (VR) intervention can be integrated within existing healthcare services for people with multiple sclerosis (MS) in the United Kingdom (UK) National Health Service (NHS). Methods Data from
Externí odkaz:
https://doaj.org/article/1508cebca26c47f08e3007b406548f93
Autor:
Yi Zhong, Ning Tan, Jordan T. Abell, Chijun Sun, Stefanie Kaboth-Bahr, Heather L. Ford, Timothy D. Herbert, Alex Pullen, Keiji Horikawa, Jimin Yu, Torben Struve, Michael E. Weber, Peter D. Clift, Juan C. Larrasoaña, Zhengyao Lu, Hu Yang, André Bahr, Tianyu Chen, Jingyu Zhang, Cao Wei, Wenyue Xia, Sheng Yang, Qingsong Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract The investigation of triggers causing the onset and intensification of Northern Hemisphere Glaciation (NHG) during the late Pliocene is essential for understanding the global climate system, with important implications for projecting future
Externí odkaz:
https://doaj.org/article/b3df6bdd873d436095d75ccadf74aeb7
Autor:
Kelsey B. Bennion, Danya Liu, Abdelhameed S. Dawood, Megan M. Wyatt, Katie L. Alexander, Mohamed S. Abdel-Hakeem, Chrystal M. Paulos, Mandy L. Ford
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The regulatory circuits dictating CD8+ T cell responsiveness versus exhaustion during anti-tumor immunity are incompletely understood. Here we report that tumor-infiltrating antigen-specific PD-1+ TCF-1− CD8+ T cells express the immunosupp
Externí odkaz:
https://doaj.org/article/ac5c51a14c4148dcaf211da0aa6ca675
Autor:
L. E. Burton, A. M. Haywood, J. C. Tindall, A. M. Dolan, D. J. Hill, E. L. McClymont, S. L. Ho, H. L. Ford
Publikováno v:
Climate of the Past, Vol 20, Pp 1177-1194 (2024)
We present the role of CO2 forcing in controlling Late Pliocene sea surface temperature (SST) change using six models from Phase 2 of the Pliocene Model Intercomparison Project (PlioMIP2) and palaeoclimate proxy data from the PlioVAR working group. A
Externí odkaz:
https://doaj.org/article/bbda1dfe238e40bdb3788ad4ce544ed4
Autor:
Alan J Thompson, Charles Wade, Nevin John, Jeremy Chataway, Gavin Giovannoni, Rachael Hunter, Sreedharan Harikrishnan, Floriana De Angelis, Olga Ciccarelli, Eli Silber, John Greenwood, Thomas Williams, Martin Duddy, Basil Sharrack, Annie Hawton, Siddharthan Chandran, Sue Pavitt, Paul Gallagher, Ian Galea, Jennifer M Nicholas, Tarunya Arun, Miriam Mattoscio, Richard Nicholas, Neil Robertson, Carolyn Young, Jeremy Hobart, David Rog, Owen Pearson, Anisha Doshi, Timothy Harrower, Leonora Fisniku, Ruth Geraldes, Nikos Evangelou, Judy Beveridge, Matthew Craner, Don Mahad, Stefano Pluchino, Suresh Chhetri, Susan Tebbs, Marie Braisher, Seema Kalra, Charles Hillier, Chris Frost, Gavin McDonnell, Stuart J Nixon, Helen L Ford, Jeban Ganesalingam, Claire Rice, Alberto Calvi, Cord Spilker, Abdullah Shehu, Martin Lee, James Blackstone, Alessia Bianchi, Agne Straukiene, Gil Barton, Fayyaz Ahmed, Dawn Lyle, Ekaterina Bordea, Sean Apap Mangion, Rachel Merry, Elisabeth Jarman
Publikováno v:
BMJ Open, Vol 14, Iss 9 (2024)
Introduction There remains a high unmet need for disease-modifying therapies that can impact disability progression in secondary progressive multiple sclerosis (SPMS). Following positive results of the phase 2 MS-STAT study, the MS-STAT2 phase 3 tria
Externí odkaz:
https://doaj.org/article/69619bde66e34a6986cbeaf0b8bdc802
Autor:
Katherine L. O’Shaughnessy, Kiersten S. Bell, Aubrey L. Sasser, Mary E. Gilbert, Cal Riutta, Jermaine L. Ford, James McCord, Carmen R. Wood
Publikováno v:
Environment International, Vol 190, Iss , Pp 108838- (2024)
Known as “forever chemicals”, per- and polyfluoroalkyl substances (PFAS) are synthetic compounds used in consumer goods but pose significant public health concerns, including disruption of the thyroid system. As thyroid hormones (THs) are require
Externí odkaz:
https://doaj.org/article/bb4198e0f99f4d2dbdb1a2cb1164bfed
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-8 (2024)
Abstract Background The majority of vector-borne disease cases in the USA are caused by pathogens spread by ticks, most commonly the blacklegged tick, Ixodes scapularis. Personal protection against tick bites, including use of repellents, is the prim
Externí odkaz:
https://doaj.org/article/b8b616eaa14b472f956f27dba368038e
Autor:
Lori C. Jordan, Allison A. King, Julie Kanter, Jeff Lebensburger, Andria L. Ford, Taniya E. Varughese, Lisa Garrett, Lauren Mullis, LeShana Saint Jean, Samantha Davis, Jeanine Dumas, Adetola A. Kassim, Mark Rodeghier, Mustapha S. Hikima, Mohammad A. Suwaid, Mohammed K. Saleh, Michael R. DeBaun
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 12 (2024)
Background Most adults with sickle cell disease will experience a silent cerebral infarction (SCI) or overt stroke. Identifying patient subgroups with increased stroke incidence is important for future clinical trials focused on stroke prevention. Ou
Externí odkaz:
https://doaj.org/article/0f36966c0c3340eb92b5a2f1eb995e9d
Autor:
Jerome C. Anyalebechi, Yini Sun, Carolyn Davis, Maylene E. Wagener, Zhe Liang, Eileen M. Burd, Craig M. Coopersmith, Mandy L. Ford
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionA hallmark of T cell dysregulation during sepsis is the downregulation of costimulatory molecules. CD28 is one of T cell costimulatory molecules significantly altered on memory T cells during sepsis. We recently showed that treatment with
Externí odkaz:
https://doaj.org/article/429754ade8b144558594280f7c10d7ec