Zobrazeno 1 - 10
of 1 576
pro vyhledávání: '"A. Kowluru"'
Autor:
M. Elizabeth Hartnett, MD, Ward Fickweiler, MD, PhD, Anthony P. Adamis, MD, Michael Brownlee, MD, Arup Das, MD, PhD, Elia J. Duh, MD, Edward P. Feener, PhD, George King, MD, Renu Kowluru, PhD, Ulrich F.O. Luhmann, PhD, Federica Storti, PhD, Charles C. Wykoff, MD, PhD, Lloyd Paul Aiello, MD, PhD
Publikováno v:
Ophthalmology Science, Vol 4, Iss 5, Pp 100521- (2024)
Purpose: Hyperglycemia is a major risk factor for early lesions of diabetic retinal disease (DRD). Updating the DRD staging system to incorporate relevant basic and cellular mechanisms pertinent to DRD is necessary to better address early disease, di
Externí odkaz:
https://doaj.org/article/d168a05b499a4366a82cce9f5b9f8421
Publikováno v:
In Free Radical Biology and Medicine 20 November 2024 225:821-832
Autor:
Hartnett, M. Elizabeth, Fickweiler, Ward, Adamis, Anthony P., Brownlee, Michael, Das, Arup, Duh, Elia J., Feener, Edward P., King, George, Kowluru, Renu, Luhmann, Ulrich F.O., Storti, Federica, Wykoff, Charles C., Aiello, Lloyd Paul
Publikováno v:
In Ophthalmology Science September-October 2024 4(5)
Autor:
Pooja Malaviya, Renu A. Kowluru
Publikováno v:
Eye and Vision, Vol 11, Iss 1, Pp 1-15 (2024)
Abstract Background Diabetic retinopathy is a progressive disease, and one of the key metabolic abnormalities in the pathogenesis of diabetic retinopathy, mitochondrial damage, is also influenced by the duration of hyperglycemia. Mitochondrial qualit
Externí odkaz:
https://doaj.org/article/1f6cdf78e85842af90ca36e540640863
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1637 (2024)
Aim: Hyperglycemia damages mitochondria and downregulates transcription of mtDNA-encoded genes and the long noncoding RNA LncCytB, causing mitochondrial genomic instability. The genes encoded by mtDNA are transcribed as large polycistronic transcript
Externí odkaz:
https://doaj.org/article/9581d8dff4024fd19b89f2f52e414073
Publikováno v:
In Molecular and Cellular Endocrinology 15 January 2024 580
Autor:
Gleason, Noah1,2 (AUTHOR) gp8205@wayne.edu, Kowluru, Anjaneyulu1,2 (AUTHOR) akowluru@med.wayne.edu
Publikováno v:
Cells (2073-4409). Feb2024, Vol. 13 Issue 3, p272. 13p.
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Hyperlipidemia is considered as one of the major systemic factors associated with the development of diabetic retinopathy, and animal models have documented that its presence in a hyperglycemic environment exacerbates cytosolic ROS productio
Externí odkaz:
https://doaj.org/article/18f99c7f57864c73b5789fca3213a58e