Zobrazeno 1 - 10
of 116
pro vyhledávání: '"A. Kousba"'
Publikováno v:
Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays ISBN: 9783030733179
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b93a64d2dc8a0c2acb2a5ba0d526419e
https://doi.org/10.1007/978-3-030-73317-9_100-1
https://doi.org/10.1007/978-3-030-73317-9_100-1
Publikováno v:
In Toxicology and Applied Pharmacology 2007 219(2):217-225
Publikováno v:
In Toxicology 2006 220(1):13-25
Publikováno v:
In Toxicology and Applied Pharmacology 2005 205(1):31-42
Publikováno v:
In Neurotoxicology 2004 25(6):1013-1030
Publikováno v:
In Toxicology 2003 188(2):219-232
Publikováno v:
In Regulatory Toxicology and Pharmacology 2003 37(1):66-72
Autor:
Jessica Hart, Alain C. Mita, John Sarantopoulos, Ahmed Kousba, Kamalesh Kumar Sankhala, Laeeq Malik, Neil Senzer, John Charles, Nicole S. Gallegos, Gavin Anderson, Steven D. Weitman, Devalingam Mahalingam, Jon M. Rogers, John Nemunaitis
Publikováno v:
Cancer Chemotherapy and Pharmacology. 74:1241-1250
ATI-1123 is a liposomal formulation of docetaxel and may be administered without the premedications and hypersensitivity reactions. This Phase I study examines the safety, tolerability, pharmacokinetics (PKs), and antitumor activity of ATI-1123.Patie
Publikováno v:
Drug Metabolism and Disposition. 35:2242-2251
[7-(2,6-Dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine (TG100435) is a novel multi-targeted Src family kinase inhibitor with demonstrated anticancer activity in preclinical species. Potent kinase inhib
Autor:
Joel Renick, Jianguo Cao, Michael D. Martin, John Doukas, Ahmed A Kousba, Binqi Zeng, John Hood, Steven Hu, Daniel L. Lohse, Xiyun Yu, Arek Tabak, Glenn Noronha, Shiyin Yee, Richard Soll, Andrew McPherson
Publikováno v:
Drug Metabolism and Disposition. 35:929-936
TG100435 ([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine) is a novel multitargeted, orally active protein tyrosine kinase inhibitor. The inhibition constants (K(i)) of TG100435 against Src, Lyn