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Akademický článek

Assessing the Utility of a Patient-Facing Diagnostic Tool Among Individuals With Hypermobile Ehlers-Danlos Syndrome: Focus Group Study

Autor: Jessica Goehringer, Abigail Kosmin, Natalie Laible, Katrina Romagnoli

Publikováno v: JMIR Formative Research, Vol 8, p e49720 (2024)

BackgroundHypermobile Ehlers-Danlos syndrome (hEDS), characterized by joint hypermobility, skin laxity, and tissue fragility, is thought to be the most common inherited connective tissue disorder, with millions affected worldwide. Diagnosing this con

Externí odkaz: https://doaj.org/article/c3e4b71fdb6546b299818383cca4d1e0

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Akademický článek

Enoch the Explorer: 1 Enoch 17–36 in Its Hellenistic Context.

Autor: Kosmin, Paul J.¹ pjkosmin@fas.harvard.edu

Publikováno v: Journal of Biblical Literature. 2024, Vol. 143 Issue 1, p67-83. 17p.

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Akademický článek

C16orf72/HAPSTR1/TAPR1 functions with BRCA1/Senataxin to modulate replication-associated R-loops and confer resistance to PARP disruption

Autor: Abhishek Bharadwaj Sharma, Muhammad Khairul Ramlee, Joel Kosmin, Martin R. Higgs, Amy Wolstenholme, George E. Ronson, Dylan Jones, Daniel Ebner, Noor Shamkhi, David Sims, Paul W. G. Wijnhoven, Josep V. Forment, Ian Gibbs-Seymour, Nicholas D. Lakin

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)

Abstract While the toxicity of PARP inhibitors to cells with defects in homologous recombination (HR) is well established, other synthetic lethal interactions with PARP1/PARP2 disruption are poorly defined. To inform on these mechanisms we conducted

Externí odkaz: https://doaj.org/article/173fc00005584212ac6ca37aec8c9ac4

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Akademický článek

Isocitrate Dehydrogenase 1/2 Wildtype Adult Astrocytoma with WHO Grade 2/3 Histological Features: Molecular Re-Classification, Prognostic Factors, Clinical Outcomes

Autor: Meetakshi Gupta, Mustafa Anjari, Sebastian Brandner, Naomi Fersht, Elena Wilson, Steffi Thust, Michael Kosmin

Publikováno v: Biomedicines, Vol 12, Iss 4, p 901 (2024)

Background: Isocitrate Dehydrogenase 1/2 (IDH 1/2)-wildtype (WT) astrocytomas constitute a heterogeneous group of tumors and have undergone a series of diagnostic reclassifications over time. This study aimed to investigate molecular markers, clinica

Externí odkaz: https://doaj.org/article/3eaf7f0854b449fab8c3c245aec3f70d

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Akademický článek

Non-functioning pituitary macroadenoma following surgery: long-term outcomes and development of an optimal follow-up strategy

Autor: Ziad Hussein, Joan Grieve, Neil Dorward, Katherine Miszkiel, Michael Kosmin, Naomi Fersht, Pierre Marc Bouloux, Zane Jaunmuktane, Stephanie E. Baldeweg, Hani J. Marcus

Publikováno v: Frontiers in Surgery, Vol 10 (2023)

ObjectivesRecurrence and regrowth of non-functioning pituitary macroadenomas (NFPMs) after surgery are common but remain unpredictable. Therefore, the optimal timing and frequency of follow-up imaging remain to be determined. We sought to determine t

Externí odkaz: https://doaj.org/article/aab8287d20b94ef18131f2955d352481

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Akademický článek

Improving the Constructive Accuracy of Pipe-Mill Machinery Through the Use of Laser 3D Systems and Mathematical Models for Data Processing.

Autor: Kosmin, I. V.¹ (AUTHOR) i.kosmin@tmk-group.com, Shkuratov, E. A.¹ (AUTHOR), Bushin, R. O.² (AUTHOR), Pyankov, K. P.² (AUTHOR), Panasenko, O. A.² (AUTHOR)

Publikováno v: Metallurgist. Nov2023, Vol. 67 Issue 7/8, p1014-1020. 7p.

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