Zobrazeno 1 - 10
of 8 120
pro vyhledávání: '"A. Kettunen"'
Autor:
von Witte, Gevin, Himmler, Aaron, Hyppönen, Viivi, Jäntti, Jiri, Albannay, Mohammed M., Moilanen, Jani O., Ernst, Matthias, Lehto, Vesa-Pekka, Riikonen, Joakim, Kozerke, Sebastian, Kettunen, Mikko I., Tamarov, Konstantin
Si nanoparticles (NPs) have been actively developed as a hyperpolarized magnetic resonance imaging (MRI) contrast agent with an imaging window close to one hour. However, the progress in the development of NPs has been hampered by the incomplete unde
Externí odkaz:
http://arxiv.org/abs/2401.08320
Autor:
Ville Salo, Juhani Määttä, Eeva Sliz, FinnGen, Ene Reimann, Reedik Mägi, Estonian Biobank Research Team, Kadri Reis, Abdelrahman G. Elhanas, Anu Reigo, Priit Palta, Tõnu Esko, Jaro Karppinen, Johannes Kettunen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Given that lumbar disc herniation (LDH) is a prevalent spinal condition that causes significant individual suffering and societal costs, the genetic basis of LDH has received relatively little research. Our aim is to increase understanding o
Externí odkaz:
https://doaj.org/article/e11fbdff18b34dd8bca25fae232611aa
Autor:
Ying-Chieh Wu, Šárka Lehtonen, Kalevi Trontti, Riitta Kauppinen, Pinja Kettunen, Ville Leinonen, Markku Laakso, Johanna Kuusisto, Mikko Hiltunen, Iiris Hovatta, Kristine Freude, Hiramani Dhungana, Jari Koistinaho, Taisia Rolova
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-20 (2024)
Abstract Background Patients with Alzheimer's disease (AD) frequently present with cerebral amyloid angiopathy (CAA), characterized by the accumulation of beta-amyloid (Aβ) within the cerebral blood vessels, leading to cerebrovascular dysfunction. P
Externí odkaz:
https://doaj.org/article/ff2355ab447b4ba585cb169fd9c26369
Autor:
Eeva Saari, Minna Mononen, Hannele Hasala, Hanna Nurmi, Hannu-Pekka Kettunen, Sanna Suoranta, Elisa Lappi-Blanco, Riitta Kaarteenaho, Minna Purokivi, Heikki Olavi Koskela
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Interstitial lung diseases (ILD) include a wide range of diseases impacting lung parenchyma and leading to fibrosis and architectural distortion. Chronic cough and dyspnea are common symptoms which affect the quality of life (QoL)
Externí odkaz:
https://doaj.org/article/f4a89e6e437548fe93aa624bc75c0af9
Autor:
Argyro Bizaki-Vallaskangas, Joel Rämö, Eeva Sliz, Ilkka Kivekäs, Tytti Willberg, Elmo Saarentaus, Sanna Toppila-Salmi, Aarno Dietz, Teppo Haapaniemi, Vesa P. Hytönen, Sari Toivola, Aarno Palotie, Antti Mäkitie, Johannes Kettunen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract To evaluate the genetics of chronic nonsuppurative otitis media (OM). We performed a genome-wide association study of 429,599 individuals included in the FinnGen study using three different case definitions: combined chronic nonsuppurative O
Externí odkaz:
https://doaj.org/article/c900bb12cbae45809bc6e06bc2152968
Autor:
Meike Hedwig Keuters, Velta Keksa-Goldsteine, Taisia Rõlova, Merja Jaronen, Pinja Kettunen, Aurora Halkoluoto, Gundars Goldsteins, Jari Koistinaho, Hiramani Dhungana
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Stroke is a leading cause of permanent disability worldwide. Despite intensive research over the last decades, key anti-inflammatory strategies that have proven beneficial in pre-clinical animal models have often failed in translation. The i
Externí odkaz:
https://doaj.org/article/e14cbe37fa6d42fea676aeada9103100
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-6 (2024)
Abstract Background Osteoarthritis in the lower extremities becomes more common as people age. In addition to conservative treatments, hip or knee arthroplasty is often needed. The aim of this study was to evaluate total knee arthroplasty (later TKA)
Externí odkaz:
https://doaj.org/article/e948a1be4de24780aaccfb31f3a8e0e1
Autor:
Rochelle N. Naylor, Kashyap A. Patel, Jarno L. T. Kettunen, Jonna M. E. Männistö, Julie Støy, Jacques Beltrand, Michel Polak, ADA/EASD PMDI, Tina Vilsbøll, Siri A. W. Greeley, Andrew T. Hattersley, Tiinamaija Tuomi
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-17 (2024)
Abstract Background Beta-cell monogenic forms of diabetes have strong support for precision medicine. We systematically analyzed evidence for precision treatments for GCK-related hyperglycemia, HNF1A-, HNF4A- and HNF1B-diabetes, and mitochondrial dia
Externí odkaz:
https://doaj.org/article/c6131c68651d4205b6f18e53add807da
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-30 (2024)
Abstract Central nervous system infections have been suggested as a possible cause for neurodegenerative diseases, particularly sporadic cases. They trigger neuroinflammation which is considered integrally involved in neurodegenerative processes. In
Externí odkaz:
https://doaj.org/article/09f48696ee7d4fe1a343dcff230c3dcf
Circuit design based on Quantum-dots Cellular Automata technology offers power-efficiency and nano-size circuits. It is an attractive alternative to CMOS technology. The XOR gate is a widely used building element in arithmetic circuits. An efficient
Externí odkaz:
http://arxiv.org/abs/2302.13946