Zobrazeno 1 - 10
of 37
pro vyhledávání: '"A. Katrin Szardenings"'
Autor:
Verena Hugenberg, Malte Behrends, Stefan Wagner, Sven Hermann, Michael Schäfers, Hartmuth C. Kolb, Katrin Szardenings, Joseph C. Walsh, Luis F. Gomez, Klaus Kopka, Günter Haufe
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 3, Iss 1, Pp 1-20 (2018)
Abstract Background To study MMP activity in vivo in disease, several radiolabeled MMP inhibitors functioning as radiotracers have been evaluated by means of SPECT and PET. Unfortunately, most of them suffer from metabolic instability, mainly hepatob
Externí odkaz:
https://doaj.org/article/f46543465c6341a8b7a69de0fcd3d048
Autor:
Hartmuth C. Kolb, Cristian Constantinescu, Michael A. Letavic, Anindya Bhattacharya, Anna Katrin Szardenings, Wei Zhang, Gilles Tamagnan, Chunfang A. Xia, Chaofeng Huang, Gang Chen, Olivier Barret
Publikováno v:
Journal of Nuclear Medicine. 60:1154-1159
The P2X7 receptor is an adenosine triphosphate-gated ion channel, which is abundantly expressed in glial cells within the central nervous system and in the periphery. P2X7 receptor activation leads to the release of the proinflammatory cytokine IL-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f20c1d914780d4020b0f900288b0ebd0
https://doi.org/10.2967/jnumed.118.212696
https://doi.org/10.2967/jnumed.118.212696
Autor:
Chaofeng Huang, Gang Chen, Yingbo He, Anna Katrin Szardenings, Michael A. Letavic, Tamara Berdyyeva, Wei Zhang, Hartmuth C. Kolb, Anindya Bhattacharya, Chunfang Xia, Natalie Taylor
Publikováno v:
Molecular Imaging and Biology. 21:871-878
The P2X7 receptor, an adenosine triphosphate (ATP)-gated purinoreceptor, has emerged as one of the key players in neuroinflammatory processes. Therefore, developing a positron emission tomography (PET) tracer for imaging of P2X7 receptors in vivo pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dba7d250b2bcabd043c8d9440586b7f1
https://doi.org/10.1007/s11307-018-01313-2
https://doi.org/10.1007/s11307-018-01313-2
Autor:
Tamara, Berdyyeva, Chunfang, Xia, Natalie, Taylor, Yingbo, He, Gang, Chen, Chaofeng, Huang, Wei, Zhang, Hartmuth, Kolb, Michael, Letavic, Anindya, Bhattacharya, Anna Katrin, Szardenings
Publikováno v:
Molecular imaging and biology. 21(5)
The P2X7 receptor, an adenosine triphosphate (ATP)-gated purinoreceptor, has emerged as one of the key players in neuroinflammatory processes. Therefore, developing a positron emission tomography (PET) tracer for imaging of P2X7 receptors in vivo pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bf6c7b87eac51e54ac47181d3a786fd6
https://pubmed.ncbi.nlm.nih.gov/30632003
https://pubmed.ncbi.nlm.nih.gov/30632003
Autor:
Jennifer Madonia, Anna Katrin Szardenings, Frederik J. R. Rombouts, Maarten Timmers, Hartmuth C. Kolb, Mark E. Schmidt, Olivier Barret, Kenneth Marek, Christine M. Sandiego, Diederik Moechars
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbb33f72f3332923f5ee09fbaf995323
https://doi.org/10.1016/j.jalz.2018.06.1063
https://doi.org/10.1016/j.jalz.2018.06.1063
Autor:
Hartmuth C, Kolb, Olivier, Barret, Anindya, Bhattacharya, Gang, Chen, Cristian, Constantinescu, Chaofeng, Huang, Michael, Letavic, Gilles, Tamagnan, Chunfang A, Xia, Wei, Zhang, Anna Katrin, Szardenings
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 60(8)
The P2X7 receptor is an adenosine triphosphate-gated ion channel, which is abundantly expressed in glial cells within the central nervous system and in the periphery. P2X7 receptor activation leads to the release of the proinflammatory cytokine IL-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42876fa67e243aa5fef77b4a95431e57
https://pubmed.ncbi.nlm.nih.gov/30733317
https://pubmed.ncbi.nlm.nih.gov/30733317
Autor:
Helen Su, Umesh B. Gangadharmath, Joseph C. Walsh, Natalia Gorodny, Fanrong Mu, Gang Chen, Balaji Tamarappoo, Daniel S. Berman, Hartmuth C. Kolb, Luis F. Gomez, Katrin Szardenings
Publikováno v:
Journal of Nuclear Cardiology. 21:553-562
Rupture of unstable atherosclerotic plaque that leads to stroke and myocardial infarction may be induced by macrophage infiltration and neovessel formation. A tracer that selectively binds to integrin αvβ3 a protein expressed by macrophages and neo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac62ecef6152864c8da907f26fb01fcb
https://doi.org/10.1007/s12350-014-9879-3
https://doi.org/10.1007/s12350-014-9879-3
Autor:
Joseph C. Walsh, A. Katrin Szardenings, Min-Ying Su, Shadfar Bahri, Hartmuth C. Kolb, William R. Shankle, Arkadij M. Elizarov, David Chien, Alan J. Lerner, Chunfang Xia, Fanrong Mu
Publikováno v:
Chien, DT; Szardenings, AK; Bahri, S; Walsh, JC; Mu, F; Xia, C; et al.(2014). Early clinical PET imaging results with the novel PHF-tau radioligand [F18]-T808. Journal of Alzheimer's Disease, 38(1), 171-184. doi: 10.3233/JAD-130098. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7q6232fs
Journal of Alzheimer's disease : JAD, vol 38, iss 1
Journal of Alzheimer's disease : JAD, vol 38, iss 1
Aggregates of hyperphosphorylated tau (PHF-tau), such as neurofibrillary tangles, are linked to the degree of cognitive impairment in Alzheimer's disease. We have recently reported early clinical results of a novel PHF-tau targeting PET imaging agent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7af0e1568c9724a1f73ba60891db3df
https://doi.org/10.3233/jad-130098
https://doi.org/10.3233/jad-130098
Autor:
Qianwa Liang, Fanrong Mu, Hartmuth C. Kolb, Gang Chen, A. Katrin Szardenings, Luis F. Gomez, Helen Su, Chunfang Xia, Vani P. Mocharla, Joseph C. Walsh, Tieming Zhao, Umesh B. Gangadharmath
Publikováno v:
Molecular Imaging and Biology. 15:748-757
A novel caspase-3 substrate-based probe [(18)F]-CP18 was evaluated as an in vivo positron emission tomography (PET) imaging agent for monitoring apoptosis in tumors.Uptake of [(18)F]-CP18 in cell assays and tumors was measured. Caspase-3/7 activities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e606848960785487621d2ccdb98044
https://doi.org/10.1007/s11307-013-0646-7
https://doi.org/10.1007/s11307-013-0646-7
Autor:
Qianwa Liang, Luis F. Gomez, Joseph C. Walsh, Hartmuth C. Kolb, Fanrong Mu, A. Katrin Szardenings, Helen Su, Chunfang Xia, Gang Chen, Vani P. Mocharla, Umesh B. Gangadharmath, Chul Yu
Publikováno v:
Molecular Imaging and Biology. 15:739-747
We identified and validated [18F]-CP18, a DEVD (the caspase 3 substrate recognition motif) containing substrate-based compound as an imaging tracer for caspase-3 activity in apoptotic cells. CP18 was radiolabeled with fluorine-18 using click chemistr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bcc5cff99ec4ce939a1db50be39b2e1
https://doi.org/10.1007/s11307-013-0644-9
https://doi.org/10.1007/s11307-013-0644-9