Zobrazeno 1 - 10
of 6 066
pro vyhledávání: '"A. Kakita"'
Autor:
Tomohiko Ishihara, Akihide Koyama, Naoki Atsuta, Mari Tada, Saori Toyoda, Kenta Kashiwagi, Sachiko Hirokawa, Yuya Hatano, Akio Yokoseki, Ryoichi Nakamura, Genki Tohnai, Yuishin Izumi, Ryuji Kaji, Mitsuya Morita, Asako Tamura, Osamu Kano, Masashi Aoki, Satoshi Kuwabara, Akiyoshi Kakita, Gen Sobue, Osamu Onodera
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-7 (2024)
Abstract Background The copy number status (CNS) of the survival motor neuron (SMN) gene may influence the risk and prognosis of amyotrophic lateral sclerosis (ALS) and lower motor neuron diseases (LMND) other than spinal muscular atrophy (SMA). Howe
Externí odkaz:
https://doaj.org/article/e6002aa4b2cd48bbb9179f2fb1b1a195
Autor:
Samuel D. Chauvin, Shoichiro Ando, Joe A. Holley, Atsushi Sugie, Fang R. Zhao, Subhajit Poddar, Rei Kato, Cathrine A. Miner, Yohei Nitta, Siddharth R. Krishnamurthy, Rie Saito, Yue Ning, Yuya Hatano, Sho Kitahara, Shin Koide, W. Alexander Stinson, Jiayuan Fu, Nehalee Surve, Lindsay Kumble, Wei Qian, Oleksiy Polishchuk, Prabhakar S. Andhey, Cindy Chiang, Guanqun Liu, Ludovic Colombeau, Raphaël Rodriguez, Nicolas Manel, Akiyoshi Kakita, Maxim N. Artyomov, David C. Schultz, P. Toby Coates, Elisha D. O. Roberson, Yasmine Belkaid, Roger A. Greenberg, Sara Cherry, Michaela U. Gack, Tristan Hardy, Osamu Onodera, Taisuke Kato, Jonathan J. Miner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)
Abstract Age-related microangiopathy, also known as small vessel disease (SVD), causes damage to the brain, retina, liver, and kidney. Based on the DNA damage theory of aging, we reasoned that genomic instability may underlie an SVD caused by dominan
Externí odkaz:
https://doaj.org/article/ca3eac3b209b443bb4c3882b9c20a335
Autor:
Atsuko Nagaoka, Mizuki Hino, Ryuta Izumi, Risa Shishido, Miki Ishibashi, Masataka Hatano, Makoto Sainouchi, Akiyoshi Kakita, Hiroaki Tomita, Yasuto Kunii
Publikováno v:
Neuropsychopharmacology Reports, Vol 44, Iss 2, Pp 399-409 (2024)
Abstract Aim Postmortem brain research is necessary for elucidating the pathology of schizophrenia; an increasing number of studies require a combination of suitable tissue samples preserved at multiple brain banks. In this study, we examined whether
Externí odkaz:
https://doaj.org/article/e19f62b72bd64341a982eb3f469f2bd4
Autor:
Takeshi Yoshimoto, Hiroshi Yamagami, Nobuyuki Sakai, Kazutaka Uchida, Manabu Shirakawa, Mikiya Beppu, Kazunori Toyoda, Yuji Matsumaru, Yasushi Matsumoto, Kenichi Todo, Mikito Hayakawa, Seigo Shindo, Masafumi Morimoto, Masataka Takeuchi, Hirotoshi Imamura, Hiroyuki Ikeda, Kanta Tanaka, Hideyuki Ishihara, Hiroto Kakita, Takanori Sano, Hayato Araki, Tatsufumi Nomura, Fumihiro Sakakibara, Shinichi Yoshimura, for RESCUE AT-LVO Investigators
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundWe aimed to clarify the association between intraoperative P2Y12 inhibitor administration during EVT and clinical outcomes in patients with anterior circulation TO stroke.MethodsAmong consecutive patients with acute ischemic stroke (AIS) en
Externí odkaz:
https://doaj.org/article/ce134efa865f4df2a47978d9de0dda70
Autor:
Qiannan Wang, Shintaro Tsuboguchi, Kouichirou Okamoto, Mari Tada, Akiyoshi Kakita, Kazuo Nakamichi, Makoto Oishi, Masato Kanazawa, Osamu Onodera
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Progressive multifocal leukoencephalopathy (PML) is a rare central nervous system disease caused by JC virus (JCV) infection. Human immunodeficiency virus (HIV) infection is the greatest risk factor for PML. Other immunological diseases, including sy
Externí odkaz:
https://doaj.org/article/97d77b9ecbdc43f5b86cb00226a51ee3
Autor:
Daiken Satake, Manabu Natsumeda, Kaishi Satomi, Mari Tada, Taro Sato, Noritaka Okubo, Keita Kawabe, Haruhiko Takahashi, Yoshihiro Tsukamoto, Masayasu Okada, Masakazu Sano, Haruko Iwabuchi, Nao Shibata, Masaru Imamura, Chihaya Imai, Hirokazu Takami, Koichi Ichimura, Ryo Nishikawa, Hajime Umezu, Akiyoshi Kakita, Makoto Oishi
Publikováno v:
Current Oncology, Vol 31, Iss 4, Pp 1831-1838 (2024)
Molecular analysis of the growing teratoma syndrome has not been extensively studied. Here, we report a 14-year-old boy with a growing mass during treatment for a mixed germ cell tumor of the pineal region. Tumor markers were negative; thus, growing
Externí odkaz:
https://doaj.org/article/0da2ebd7e2c04fa6ba30f6615b16a2c8
Autor:
Mizuki Hino, Yasuto Kunii, Risa Shishido, Atsuko Nagaoka, Junya Matsumoto, Hiroyasu Akatsu, Yoshio Hashizume, Hideki Hayashi, Akiyoshi Kakita, Hiroaki Tomita, Hirooki Yabe
Publikováno v:
Neuropsychopharmacology Reports, Vol 44, Iss 1, Pp 121-128 (2024)
Abstract Aim The etiology of bipolar disorder (BD) remains unknown; however, lipid abnormalities in BD have received increasing attention in recent years. In this study, we examined the expression levels of enzyme proteins associated with the metabol
Externí odkaz:
https://doaj.org/article/6e606ffe19e94b8daa0f3078d123b804
Autor:
Takayuki Sakai, Aya Ogata, Hiroshi Ikenuma, Takashi Yamada, Saori Hattori, Junichiro Abe, Shinichi Imamura, Masanori Ichise, Mari Tada, Akiyoshi Kakita, Hiroko Koyama, Masaaki Suzuki, Takashi Kato, Kengo Ito, Yasuyuki Kimura
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract Background Heat shock proteins (HSPs) are present throughout the brain. They function as molecular chaperones, meaning they help with the folding and unfolding of large protein complexes. These chaperones are vital in the development of neur
Externí odkaz:
https://doaj.org/article/7e5c56ae5ca04ac88d65512c7d7c7460
Autor:
Satoshi Kurita, Takehiko Doi, Kenji Harada, Masanori Morikawa, Chiharu Nishijima, Kazuya Fujii, Daisuke Kakita, Hiroyuki Shimada
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e33080- (2024)
Background: A previous study suggested older drivers with subjective memory concerns (SMC) had increased odds of experiencing car collisions, but whether SMC in different contexts and the number of SMC applicable items change this association is unkn
Externí odkaz:
https://doaj.org/article/fb7f77eff95044438f649c2bd19759f5
Autor:
Kentaro Suzuki, Hidetaka Onodera, Rie Sugiyama, Seiji Okubo, Naoto Kimura, Shogo Kaku, Rieko Seki, Satoshi Fujita, Koichi Nomura, Taiki Takagiwa, Izumi Katafuchi, Homare Nakamura, Takuya Kanamaru, Momoyo Oda, Shohei Kimura, Shota Sonoda, Hiroto Kakita, Toshiaki Otsuka, Kazumi Kimura
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
RationaleEnteral nutrition is beneficial for stroke patients with oral intake difficulties. However, it is time consuming and may interfere with routine medical care. Therefore, there is a clinical benefit if enteral nutrition can be safely administe
Externí odkaz:
https://doaj.org/article/81b9fd937c4145ee84cd1834d445609b