Zobrazeno 1 - 10
of 94
pro vyhledávání: '"A. K. Shaytan"'
Autor:
T. S. Trifonova, A. V. Moiseenko, M. V. Bourkaltseva, O. V. Shaburova, A. K. Shaytan, V. N. Krylov, O. S. Sokolova
Publikováno v:
Вопросы вирусологии, Vol 66, Iss 6, Pp 434-441 (2022)
Introduction. Giant phiKZ-like bacteriophages have a unique protein formation inside the capsid, an inner body (IB) with supercoiled DNA molecule wrapped around it. Standard cryo-electron microscopy (cryo-EM) approaches do not allow to distinguish th
Externí odkaz:
https://doaj.org/article/bd754d7e85204fbf91c188d4460eb552
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
In the last decade, the CRISPR-Cas technology has gained widespread popularity in different fields from genome editing and detecting specific DNA/RNA sequences to gene expression control. At the heart of this technology is the ability of CRISPR-Cas c
Externí odkaz:
https://doaj.org/article/486c98b06bd14ca68be35feae71090b8
Autor:
Ruth L. Seal, Paul Denny, Elspeth A. Bruford, Anna K. Gribkova, David Landsman, William F. Marzluff, Monica McAndrews, Anna R. Panchenko, Alexey K. Shaytan, Paul B. Talbert
Publikováno v:
Epigenetics & Chromatin, Vol 15, Iss 1, Pp 1-18 (2022)
Abstract Histones have a long history of research in a wide range of species, leaving a legacy of complex nomenclature in the literature. Community-led discussions at the EMBO Workshop on Histone Variants in 2011 resulted in agreement amongst experts
Externí odkaz:
https://doaj.org/article/f287c4639f8f4abd8d8b16c3ae2e210e
Autor:
Anastasiia L. Sivkina, Maria G. Karlova, Maria E. Valieva, Laura L. McCullough, Timothy Formosa, Alexey K. Shaytan, Alexey V. Feofanov, Mikhail P. Kirpichnikov, Olga S. Sokolova, Vasily M. Studitsky
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
Sivkina et al. present a biochemical and biophysical characterization of the interaction of S. cerevisiae histone chaperone FACT with the nucleosome core particle. They show that FACT adopts a more open geometry in the presence of Nhp6, and together
Externí odkaz:
https://doaj.org/article/a6b17f84681e4269915f8db9da80afb0
Autor:
Grigoriy A. Armeev, Anastasiia S. Kniazeva, Galina A. Komarova, Mikhail P. Kirpichnikov, Alexey K. Shaytan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nucleosomes tightly wrap ~147 DNA base pairs around an octamer of histone proteins, but how nucleosome structural dynamics affect genome functioning is not completely clear. Here authors employ all-atom molecular dynamics simulations of nucleosome co
Externí odkaz:
https://doaj.org/article/2f1e4c2fcfc146acb72bcb475cf9ee2e
Autor:
G. D. Laptev, D. K. Shaytan
Publikováno v:
Управленческие науки, Vol 8, Iss 4, Pp 67-76 (2019)
A high percentage of failures of new products is considerably associated with management issues at the initial, with a large amount of uncertainty, stage of product development. Taking into account the fact that the characteristics and functionality
Externí odkaz:
https://doaj.org/article/116f4e16f6794aa89e329557ae589684
Autor:
Han-Wen Chang, Alexey V. Feofanov, Alexander V. Lyubitelev, Grigory A. Armeev, Elena Y. Kotova, Fu-Kai Hsieh, Mikhail P. Kirpichnikov, Alexey K. Shaytan, Vasily M. Studitsky
Publikováno v:
Cells, Vol 11, Iss 16, p 2475 (2022)
Histone N-terminal tails and their post-translational modifications affect various biological processes, often in a context-specific manner; the underlying mechanisms are poorly studied. Here, the role of individual N-terminal tails of histones H2A/H
Externí odkaz:
https://doaj.org/article/93606d7b46b7459aa3494a6bed92aa5b
Autor:
Nadezhda S. Gerasimova, Olesya I. Volokh, Nikolay A. Pestov, Grigory A. Armeev, Mikhail P. Kirpichnikov, Alexey K. Shaytan, Olga S. Sokolova, Vasily M. Studitsky
Publikováno v:
Cells, Vol 11, Iss 17, p 2678 (2022)
Transcription through chromatin by RNA polymerase II (Pol II) is accompanied by the formation of small intranucleosomal DNA loops containing the enzyme (i-loops) that are involved in survival of core histones on the DNA and arrest of Pol II during th
Externí odkaz:
https://doaj.org/article/f9dba86fed324b2b87de5486430e18a2
Autor:
Arjan Hada, Swetansu K. Hota, Jie Luo, Yuan-chi Lin, Seyit Kale, Alexey K. Shaytan, Saurabh K. Bhardwaj, Jim Persinger, Jeff Ranish, Anna R. Panchenko, Blaine Bartholomew
Publikováno v:
Cell Reports, Vol 28, Iss 1, Pp 282-294.e6 (2019)
Summary: Nucleosomes are the fundamental building blocks of chromatin that regulate DNA access and are composed of histone octamers. ATP-dependent chromatin remodelers like ISW2 regulate chromatin access by translationally moving nucleosomes to diffe
Externí odkaz:
https://doaj.org/article/df5b83288cdc4244b5a12986e40788f3
Publikováno v:
International Journal of Biomedicine, Vol 9, Iss Suppl_1, Pp S25-S25 (2019)
Background: Variations in the sequence of linker histone (LH) H1 play an important role in the modulation of chromatin functioning. Meanwhile, an effect of LH variations on the chromatin structure remains unclear. The most common mutations of the cor
Externí odkaz:
https://doaj.org/article/a553ff2248584292a76197a14e177dec