Zobrazeno 1 - 10
of 365
pro vyhledávání: '"A. K. ST. CLAIR"'
Autor:
Meagan S. Kingren, Alexander R. Keeble, Alyson M. Galvan-Lara, Jodi M. Ogle, Zoltán Ungvári, Daret K. St Clair, Timothy A. Butterfield, Allison M. Owen, Christopher S. Fry, Samir P. Patel, Hiroshi Saito
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-17 (2024)
Abstract Background Sepsis, mainly caused by bacterial infections, is the leading cause of in-patient hospitalizations. After discharge, most sepsis survivors suffer from long-term medical complications, particularly chronic skeletal muscle weakness.
Externí odkaz:
https://doaj.org/article/2a5851bddea14470973d44fc590c574b
Autor:
Daniel H. Chitwood, Efrain Torres‐Lomas, Ebi S. Hadi, Wolfgang L. G. Peterson, Mirjam F. Fischer, Sydney E. Rogers, Chuan He, Michael G. F. Acierno, Shintaro Azumaya, Seth Wayne Benjamin, Devendra Prasad Chalise, Ellice E. Chess, Alex J. Engelsma, Qiuyi Fu, Jirapa Jaikham, Bridget M. Knight, Nikita S. Kodjak, Adazsofia Lengyel, Brenda L. Muñoz, Justin T. Patterson, Sundara I. Rincon, Francis L. Schumann, Yujie Shi, Charlie C. Smith, Mallory K. St. Clair, Carly S. Sweeney, Patrick Whitaker, James Wu, Luis Diaz‐Garcia
Publikováno v:
Plants, People, Planet, Vol 7, Iss 1, Pp 133-146 (2025)
Societal Impact Statement Grapevine leaves are emblematic of the strong visual associations people make with plants. Leaf shape is immediately recognizable at a glance, and therefore, this is used to distinguish grape varieties. In an era of computat
Externí odkaz:
https://doaj.org/article/985054801be4423eb8a6e896cc79abe9
Autor:
Daisuke Masuda, Ikuo Nakanishi, Kei Ohkubo, Hiromu Ito, Ken-ichiro Matsumoto, Hiroshi Ichikawa, Moragot Chatatikun, Wiyada Kwanhian Klangbud, Manas Kotepui, Motoki Imai, Fumitaka Kawakami, Makoto Kubo, Hirofumi Matsui, Jitbanjong Tangpong, Takafumi Ichikawa, Toshihiko Ozawa, Hsiu-Chuan Yen, Daret K. St Clair, Hiroko P. Indo, Hideyuki J. Majima
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 128 (2024)
Questions about which reactive oxygen species (ROS) or reactive nitrogen species (RNS) can escape from the mitochondria and activate signals must be addressed. In this study, two parameters, the calculated dipole moment (debye, D) and permeability co
Externí odkaz:
https://doaj.org/article/2f9fcb72f1c247bc85463ff752e569d2
Hydrogen Peroxide Promotes the Production of Radiation-Derived EVs Containing Mitochondrial Proteins
Autor:
Caitlin E. Miller, Fangfang Xu, Yanming Zhao, Wei Luo, Weixiong Zhong, Kristy Meyer, Rani Jayswal, Heidi L. Weiss, William H. St. Clair, Daret K. St. Clair, Luksana Chaiswing
Publikováno v:
Antioxidants, Vol 11, Iss 11, p 2119 (2022)
In spite of extensive successes, cancer recurrence after radiation treatment (RT) remains one of the significant challenges in the cure of localized prostate cancer (PCa). This study focuses on elucidating a novel adaptive response to RT that could c
Externí odkaz:
https://doaj.org/article/b36859d375574e75a78a63fbca9bb225
Publikováno v:
Antioxidants, Vol 11, Iss 6, p 1194 (2022)
Oxidative stress plays a significant role in cancer development and cancer therapy, and is a major contributor to normal tissue injury. The unique characteristics of extracellular vesicles (EVs) have made them potentially useful as a diagnostic tool
Externí odkaz:
https://doaj.org/article/6973e1a30e2b4e4a926c448c34444e37
Autor:
Sudha Sharma, Susmita Bhattarai, Hosne Ara, Grace Sun, Daret K. St Clair, Md Shenuarin Bhuiyan, Christopher Kevil, Megan N. Watts, Paari Dominic, Takahiko Shimizu, Kevin J. McCarthy, Hong Sun, Manikandan Panchatcharam, Sumitra Miriyala
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101740- (2020)
Electrophilic aldehyde (4-hydroxynonenal; 4-HNE), formed after lipid peroxidation, is a mediator of mitochondrial dysfunction and implicated in both the pathogenesis and the progression of cardiovascular disease. Manganese superoxide dismutase (MnSOD
Externí odkaz:
https://doaj.org/article/2e80799244c74b9aa7443b34abaa0a5a
Autor:
Chontida Yarana, Hannah Thompson, Luksana Chaiswing, D. Allan Butterfield, Heidi Weiss, Subbarao Bondada, Sara Alhakeem, Suriyan Sukati, Daret K. St. Clair
Publikováno v:
Redox Biology, Vol 26, Iss , Pp - (2019)
Extracellular vesicles (EVs) generated from redox active anticancer drugs are released into the extracellular environment. These EVs contain oxidized molecules and trigger inflammatory responses by macrophages. Using a mouse model of doxorubicin (DOX
Externí odkaz:
https://doaj.org/article/98e908279b00465d8862dbf696cd086c
Publikováno v:
Free Radic Biol Med
Mitochondria are central to the metabolic circuitry that generates superoxide radicals/anions (O(2)(•−)) as a by-product of oxygen metabolism. By regulating superoxide levels, manganese superoxide dismutase plays important roles in numerous bioch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8222a45380045de07487893fda38075c
https://doi.org/10.1016/j.freeradbiomed.2021.12.309
https://doi.org/10.1016/j.freeradbiomed.2021.12.309
Autor:
Daret K. St. Clair, Haining Zhu, D. Allan Butterfield, Jeffrey A. Moscow, Emily V. Dressler, Younsoo Bae, Michael Alstott, Teresa Noel, Yanming Zhao, Luksana Chaiswing, Jing Chen, Dustin Carroll, Chontida Yarana
Proteins identified in both SAL_EVs and DOX_EVs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a8c28d61a2b38dd4f7edbdf3ab32c9b
https://doi.org/10.1158/1078-0432.22464716.v1
https://doi.org/10.1158/1078-0432.22464716.v1
Autor:
Daret K. St. Clair, Haining Zhu, D. Allan Butterfield, Jeffrey A. Moscow, Emily V. Dressler, Younsoo Bae, Michael Alstott, Teresa Noel, Yanming Zhao, Luksana Chaiswing, Jing Chen, Dustin Carroll, Chontida Yarana
Purpose: Cardiac injury is a major cause of death in cancer survivors, and biomarkers for it are detectable only after tissue injury has occurred. Extracellular vesicles (EV) remove toxic biomolecules from tissues and can be detected in the blood. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::507196a27a017f9e03f97b62b35a4a2d
https://doi.org/10.1158/1078-0432.c.6525785
https://doi.org/10.1158/1078-0432.c.6525785